Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue.

Hdl Handle:
http://hdl.handle.net/10147/229146
Title:
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue.
Authors:
Kennedy, Richard D; Bylesjo, Max; Kerr, Peter; Davison, Timothy; Black, Julie M; Kay, Elaine W; Holt, Robert J; Proutski, Vitali; Ahdesmaki, Miika; Farztdinov, Vadim; Goffard, Nicolas; Hey, Peter; McDyer, Fionnuala; Mulligan, Karl; Mussen, Julie; O'Brien, Eamonn; Oliver, Gavin; Walker, Steven M; Mulligan, Jude M; Wilson, Claire; Winter, Andreas; O'Donoghue, Diarmuid; Mulcahy, Hugh; O'Sullivan, Jacintha; Sheahan, Kieran; Hyland, John; Dhir, Rajiv; Bathe, Oliver F; Winqvist, Ola; Manne, Upender; Shanmugam, Chandrakumar; Ramaswamy, Sridhar; Leon, Eduardo J; Smith, William I; McDermott, Ultan; Wilson, Richard H; Longley, Daniel; Marshall, John; Cummins, Robert; Sargent, Daniel J; Johnston, Patrick G; Harkin, D Paul
Affiliation:
Centre for Cancer Research & Cell Biology, Queen's University Belfast, Northern Ireland, United Kingdom.
Citation:
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. 2011, 29 (35):4620-6 J. Clin. Oncol.
Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Issue Date:
10-Dec-2011
URI:
http://hdl.handle.net/10147/229146
DOI:
10.1200/JCO.2011.35.4498
PubMed ID:
22067406
Abstract:
Current prognostic factors are poor at identifying patients at risk of disease recurrence after surgery for stage II colon cancer. Here we describe a DNA microarray-based prognostic assay using clinically relevant formalin-fixed paraffin-embedded (FFPE) samples.
Item Type:
Article
Language:
en
MeSH:
Aged; Colonic Neoplasms; Female; Formaldehyde; Gene Expression Profiling; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oligonucleotide Array Sequence Analysis; Paraffin Embedding; Prognosis; Retrospective Studies; Risk Factors; Tissue Fixation
ISSN:
1527-7755

Full metadata record

DC FieldValue Language
dc.contributor.authorKennedy, Richard Den_GB
dc.contributor.authorBylesjo, Maxen_GB
dc.contributor.authorKerr, Peteren_GB
dc.contributor.authorDavison, Timothyen_GB
dc.contributor.authorBlack, Julie Men_GB
dc.contributor.authorKay, Elaine Wen_GB
dc.contributor.authorHolt, Robert Jen_GB
dc.contributor.authorProutski, Vitalien_GB
dc.contributor.authorAhdesmaki, Miikaen_GB
dc.contributor.authorFarztdinov, Vadimen_GB
dc.contributor.authorGoffard, Nicolasen_GB
dc.contributor.authorHey, Peteren_GB
dc.contributor.authorMcDyer, Fionnualaen_GB
dc.contributor.authorMulligan, Karlen_GB
dc.contributor.authorMussen, Julieen_GB
dc.contributor.authorO'Brien, Eamonnen_GB
dc.contributor.authorOliver, Gavinen_GB
dc.contributor.authorWalker, Steven Men_GB
dc.contributor.authorMulligan, Jude Men_GB
dc.contributor.authorWilson, Claireen_GB
dc.contributor.authorWinter, Andreasen_GB
dc.contributor.authorO'Donoghue, Diarmuiden_GB
dc.contributor.authorMulcahy, Hughen_GB
dc.contributor.authorO'Sullivan, Jacinthaen_GB
dc.contributor.authorSheahan, Kieranen_GB
dc.contributor.authorHyland, Johnen_GB
dc.contributor.authorDhir, Rajiven_GB
dc.contributor.authorBathe, Oliver Fen_GB
dc.contributor.authorWinqvist, Olaen_GB
dc.contributor.authorManne, Upenderen_GB
dc.contributor.authorShanmugam, Chandrakumaren_GB
dc.contributor.authorRamaswamy, Sridharen_GB
dc.contributor.authorLeon, Eduardo Jen_GB
dc.contributor.authorSmith, William Ien_GB
dc.contributor.authorMcDermott, Ultanen_GB
dc.contributor.authorWilson, Richard Hen_GB
dc.contributor.authorLongley, Danielen_GB
dc.contributor.authorMarshall, Johnen_GB
dc.contributor.authorCummins, Roberten_GB
dc.contributor.authorSargent, Daniel Jen_GB
dc.contributor.authorJohnston, Patrick Gen_GB
dc.contributor.authorHarkin, D Paulen_GB
dc.date.accessioned2012-06-15T13:53:01Z-
dc.date.available2012-06-15T13:53:01Z-
dc.date.issued2011-12-10-
dc.identifier.citationDevelopment and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. 2011, 29 (35):4620-6 J. Clin. Oncol.en_GB
dc.identifier.issn1527-7755-
dc.identifier.pmid22067406-
dc.identifier.doi10.1200/JCO.2011.35.4498-
dc.identifier.urihttp://hdl.handle.net/10147/229146-
dc.description.abstractCurrent prognostic factors are poor at identifying patients at risk of disease recurrence after surgery for stage II colon cancer. Here we describe a DNA microarray-based prognostic assay using clinically relevant formalin-fixed paraffin-embedded (FFPE) samples.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Journal of clinical oncology : official journal of the American Society of Clinical Oncologyen_GB
dc.subject.meshAged-
dc.subject.meshColonic Neoplasms-
dc.subject.meshFemale-
dc.subject.meshFormaldehyde-
dc.subject.meshGene Expression Profiling-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNeoplasm Recurrence, Local-
dc.subject.meshNeoplasm Staging-
dc.subject.meshOligonucleotide Array Sequence Analysis-
dc.subject.meshParaffin Embedding-
dc.subject.meshPrognosis-
dc.subject.meshRetrospective Studies-
dc.subject.meshRisk Factors-
dc.subject.meshTissue Fixation-
dc.titleDevelopment and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue.en_GB
dc.typeArticleen
dc.contributor.departmentCentre for Cancer Research & Cell Biology, Queen's University Belfast, Northern Ireland, United Kingdom.en_GB
dc.identifier.journalJournal of clinical oncology : official journal of the American Society of Clinical Oncologyen_GB
dc.description.provinceLeinsteren

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.