Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors.

Hdl Handle:
http://hdl.handle.net/10147/229135
Title:
Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors.
Authors:
Toumi, F; Frankson, M; Ward, J B; Kelly, O B; Mroz, M S; Bertelsen, L S; Keely, S J
Affiliation:
Department of Molecular Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Citation:
Chronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. 2011, 23 (2):178-86, e43 Neurogastroenterol. Motil.
Journal:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
Issue Date:
Feb-2011
URI:
http://hdl.handle.net/10147/229135
DOI:
10.1111/j.1365-2982.2010.01610.x
PubMed ID:
20939850
Additional Links:
http://www.google.ie/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&ved=0CFMQFjAA&url=http%3A%2F%2Fepubs.rcsi.ie%2Fcgi%2Fviewcontent.cgi%3Farticle%3D1019%26context%3Dmolmedart&ei=VTfbT-OBNoHH0QW-8qziCg&usg=AFQjCNG5PlwP2uCWElVrmyUzPqDPNiWQkA&sig2=BItO3smKVi6C06MMp6-xCA
Abstract:
Enteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion. Here we examined if acute GPCR activation might have more long-term consequences for epithelial secretory function.
Item Type:
Article
Language:
en
MeSH:
Adenocarcinoma; Calcium; Carbachol; Cell Line, Tumor; Chlorides; Colonic Neoplasms; Epithelial Cells; Forskolin; Histamine; Humans; Patch-Clamp Techniques; Protein Kinase C; Receptor, Muscarinic M3; Receptors, G-Protein-Coupled; Thapsigargin
ISSN:
1365-2982

Full metadata record

DC FieldValue Language
dc.contributor.authorToumi, Fen_GB
dc.contributor.authorFrankson, Men_GB
dc.contributor.authorWard, J Ben_GB
dc.contributor.authorKelly, O Ben_GB
dc.contributor.authorMroz, M Sen_GB
dc.contributor.authorBertelsen, L Sen_GB
dc.contributor.authorKeely, S Jen_GB
dc.date.accessioned2012-06-15T13:30:49Z-
dc.date.available2012-06-15T13:30:49Z-
dc.date.issued2011-02-
dc.identifier.citationChronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors. 2011, 23 (2):178-86, e43 Neurogastroenterol. Motil.en_GB
dc.identifier.issn1365-2982-
dc.identifier.pmid20939850-
dc.identifier.doi10.1111/j.1365-2982.2010.01610.x-
dc.identifier.urihttp://hdl.handle.net/10147/229135-
dc.description.abstractEnteric neurotransmitters that act at G protein-coupled receptors (GPCRs) are well known to acutely promote epithelial Cl(-) and fluid secretion. Here we examined if acute GPCR activation might have more long-term consequences for epithelial secretory function.en_GB
dc.language.isoenen
dc.relation.urlhttp://www.google.ie/url?sa=t&rct=j&q=&esrc=s&frm=1&source=web&cd=1&ved=0CFMQFjAA&url=http%3A%2F%2Fepubs.rcsi.ie%2Fcgi%2Fviewcontent.cgi%3Farticle%3D1019%26context%3Dmolmedart&ei=VTfbT-OBNoHH0QW-8qziCg&usg=AFQjCNG5PlwP2uCWElVrmyUzPqDPNiWQkA&sig2=BItO3smKVi6C06MMp6-xCAen_GB
dc.rightsArchived with thanks to Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Societyen_GB
dc.subject.meshAdenocarcinoma-
dc.subject.meshCalcium-
dc.subject.meshCarbachol-
dc.subject.meshCell Line, Tumor-
dc.subject.meshChlorides-
dc.subject.meshColonic Neoplasms-
dc.subject.meshEpithelial Cells-
dc.subject.meshForskolin-
dc.subject.meshHistamine-
dc.subject.meshHumans-
dc.subject.meshPatch-Clamp Techniques-
dc.subject.meshProtein Kinase C-
dc.subject.meshReceptor, Muscarinic M3-
dc.subject.meshReceptors, G-Protein-Coupled-
dc.subject.meshThapsigargin-
dc.titleChronic regulation of colonic epithelial secretory function by activation of G protein-coupled receptors.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Molecular Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.en_GB
dc.identifier.journalNeurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Societyen_GB
dc.description.provinceLeinsteren
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