The impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease.

Hdl Handle:
http://hdl.handle.net/10147/228832
Title:
The impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease.
Authors:
Drew, Richard J; Ó Maoldomhnaigh, Cilian; Gavin, Patrick J; O' Sullivan, Nicola; Butler, Karina M; Cafferkey, Mary
Affiliation:
Irish Meningococcal and Meningitis Reference Laboratory (IMMRL), The Children's University Hospital, Dublin, Ireland. richard.drew@alderhey.nhs.uk
Citation:
The impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease. 2012, 31 (3):316-8 Pediatr. Infect. Dis. J.
Journal:
The Pediatric infectious disease journal
Issue Date:
Mar-2012
URI:
http://hdl.handle.net/10147/228832
DOI:
10.1097/INF.0b013e318241f824
PubMed ID:
22173139
Abstract:
Laboratory methods of diagnosis were examined for 266 children with invasive meningococcal disease. Seventy-five (36%) of 207 cases with bloodstream infection had both positive blood culture and blood meningococcal polymerase chain reaction (PCR), 130 (63%) negative blood culture and positive blood PCR, and 2 (1%) had positive blood culture and negative blood PCR. Sixty-three percent of cases were diagnosed by PCR alone.
Item Type:
Article
Language:
en
MeSH:
Bacteremia; Bacteriological Techniques; Blood; Child, Preschool; Female; Humans; Infant; Male; Meningitis, Meningococcal; Meningococcal Infections; Molecular Diagnostic Techniques; Polymerase Chain Reaction; Sensitivity and Specificity
ISSN:
1532-0987

Full metadata record

DC FieldValue Language
dc.contributor.authorDrew, Richard Jen_GB
dc.contributor.authorÓ Maoldomhnaigh, Cilianen_GB
dc.contributor.authorGavin, Patrick Jen_GB
dc.contributor.authorO' Sullivan, Nicolaen_GB
dc.contributor.authorButler, Karina Men_GB
dc.contributor.authorCafferkey, Maryen_GB
dc.date.accessioned2012-06-13T16:21:24Z-
dc.date.available2012-06-13T16:21:24Z-
dc.date.issued2012-03-
dc.identifier.citationThe impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease. 2012, 31 (3):316-8 Pediatr. Infect. Dis. J.en_GB
dc.identifier.issn1532-0987-
dc.identifier.pmid22173139-
dc.identifier.doi10.1097/INF.0b013e318241f824-
dc.identifier.urihttp://hdl.handle.net/10147/228832-
dc.description.abstractLaboratory methods of diagnosis were examined for 266 children with invasive meningococcal disease. Seventy-five (36%) of 207 cases with bloodstream infection had both positive blood culture and blood meningococcal polymerase chain reaction (PCR), 130 (63%) negative blood culture and positive blood PCR, and 2 (1%) had positive blood culture and negative blood PCR. Sixty-three percent of cases were diagnosed by PCR alone.-
dc.language.isoenen
dc.rightsArchived with thanks to The Pediatric infectious disease journalen_GB
dc.subject.meshBacteremia-
dc.subject.meshBacteriological Techniques-
dc.subject.meshBlood-
dc.subject.meshChild, Preschool-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshInfant-
dc.subject.meshMale-
dc.subject.meshMeningitis, Meningococcal-
dc.subject.meshMeningococcal Infections-
dc.subject.meshMolecular Diagnostic Techniques-
dc.subject.meshPolymerase Chain Reaction-
dc.subject.meshSensitivity and Specificity-
dc.titleThe impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease.en_GB
dc.typeArticleen
dc.contributor.departmentIrish Meningococcal and Meningitis Reference Laboratory (IMMRL), The Children's University Hospital, Dublin, Ireland. richard.drew@alderhey.nhs.uken_GB
dc.identifier.journalThe Pediatric infectious disease journalen_GB

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