Long-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide.

Hdl Handle:
http://hdl.handle.net/10147/226379
Title:
Long-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide.
Authors:
Abulhul, Esam; McDonald, Kenneth; Martos, Ramon; Phelan, Dermot; Spiers, J Paul; Hennessy, Martina; Baugh, John; Watson, Chris; O'Loughlin, Christina; Ledwidge, Mark
Affiliation:
HF Unit, St Vincent's University Hospital, Elm Park, Dublin, Ireland.
Citation:
Long-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide. 2012, 34 (1):91-100 Clin Ther
Journal:
Clinical therapeutics
Issue Date:
Jan-2012
URI:
http://hdl.handle.net/10147/226379
DOI:
10.1016/j.clinthera.2011.11.002
PubMed ID:
22154198
Abstract:
The role of statin therapy in heart failure (HF) is unclear. The amino-terminal propeptide of procollagen type III (PIIINP) predicts outcome in HF, and yet there are conflicting reports of statin therapy effects on PIIINP.
Item Type:
Article
Language:
en
MeSH:
Aged; Aged, 80 and over; Analysis of Variance; Biological Markers; Chi-Square Distribution; Cholesterol; Collagen; Collagen Type I; Down-Regulation; Female; Heart Failure, Systolic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Ireland; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Peptides; Procollagen; Prospective Studies; Pyrroles; Recovery of Function; Stroke Volume; Time Factors; Treatment Outcome; Up-Regulation; Ventricular Function, Left
ISSN:
1879-114X

Full metadata record

DC FieldValue Language
dc.contributor.authorAbulhul, Esamen_GB
dc.contributor.authorMcDonald, Kennethen_GB
dc.contributor.authorMartos, Ramonen_GB
dc.contributor.authorPhelan, Dermoten_GB
dc.contributor.authorSpiers, J Paulen_GB
dc.contributor.authorHennessy, Martinaen_GB
dc.contributor.authorBaugh, Johnen_GB
dc.contributor.authorWatson, Chrisen_GB
dc.contributor.authorO'Loughlin, Christinaen_GB
dc.contributor.authorLedwidge, Marken_GB
dc.date.accessioned2012-05-29T11:33:38Z-
dc.date.available2012-05-29T11:33:38Z-
dc.date.issued2012-01-
dc.identifier.citationLong-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide. 2012, 34 (1):91-100 Clin Theren_GB
dc.identifier.issn1879-114X-
dc.identifier.pmid22154198-
dc.identifier.doi10.1016/j.clinthera.2011.11.002-
dc.identifier.urihttp://hdl.handle.net/10147/226379-
dc.description.abstractThe role of statin therapy in heart failure (HF) is unclear. The amino-terminal propeptide of procollagen type III (PIIINP) predicts outcome in HF, and yet there are conflicting reports of statin therapy effects on PIIINP.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Clinical therapeuticsen_GB
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshAnalysis of Variance-
dc.subject.meshBiological Markers-
dc.subject.meshChi-Square Distribution-
dc.subject.meshCholesterol-
dc.subject.meshCollagen-
dc.subject.meshCollagen Type I-
dc.subject.meshDown-Regulation-
dc.subject.meshFemale-
dc.subject.meshHeart Failure, Systolic-
dc.subject.meshHeptanoic Acids-
dc.subject.meshHumans-
dc.subject.meshHydroxymethylglutaryl-CoA Reductase Inhibitors-
dc.subject.meshInflammation Mediators-
dc.subject.meshIreland-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshNatriuretic Peptide, Brain-
dc.subject.meshPeptide Fragments-
dc.subject.meshPeptides-
dc.subject.meshProcollagen-
dc.subject.meshProspective Studies-
dc.subject.meshPyrroles-
dc.subject.meshRecovery of Function-
dc.subject.meshStroke Volume-
dc.subject.meshTime Factors-
dc.subject.meshTreatment Outcome-
dc.subject.meshUp-Regulation-
dc.subject.meshVentricular Function, Left-
dc.titleLong-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide.en_GB
dc.typeArticleen
dc.contributor.departmentHF Unit, St Vincent's University Hospital, Elm Park, Dublin, Ireland.en_GB
dc.identifier.journalClinical therapeuticsen_GB
dc.description.provinceLeinsteren

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