Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda.

Hdl Handle:
http://hdl.handle.net/10147/222413
Title:
Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda.
Authors:
Agwu, Ezera; Ihongbe, John C; McManus, Brenda A; Moran, Gary P; Coleman, David C; Sullivan, Derek J
Affiliation:
School of Allied Health Sciences, Kampala International University, Republic of Uganda.
Citation:
Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda. 2012, 50 (3):276-80 Med. Mycol.
Journal:
Medical mycology : official publication of the International Society for Human and Animal Mycology
Issue Date:
Apr-2012
URI:
http://hdl.handle.net/10147/222413
DOI:
10.3109/13693786.2011.604862
PubMed ID:
21905950
Abstract:
Oropharyngeal candidiasis remains a significant clinical problem in HIV-infected and AIDS patients in regions of Africa where anti-retroviral therapy isn't readily available. In this study we identified the yeast populations associated with oral lesions in HIV-infected patients in Southwest Uganda who were receiving treatment with nystatin and topical clotrimazole. Samples were taken from 605 patients and 316 (52%) of these yielded yeast growth following incubation on Sabouraud dextrose agar. Samples were subsequently re-plated on CHROMagar Candida medium to facilitate identification of the yeast species present. The majority (56%) of culture-positive samples yielded a mix of two or more species. Candida albicans was present in 87% (274/316) of patient samples and accounted for 87% (120/138) of single species samples. Candida glabrata, Candida tropicalis and Candida norvegensis were also found in cultures that yielded a single species. No Candida dubliniensis isolates were identified in this population.
Item Type:
Article
Language:
en
ISSN:
1460-2709

Full metadata record

DC FieldValue Language
dc.contributor.authorAgwu, Ezeraen_GB
dc.contributor.authorIhongbe, John Cen_GB
dc.contributor.authorMcManus, Brenda Aen_GB
dc.contributor.authorMoran, Gary Pen_GB
dc.contributor.authorColeman, David Cen_GB
dc.contributor.authorSullivan, Derek Jen_GB
dc.date.accessioned2012-05-08T11:14:20Z-
dc.date.available2012-05-08T11:14:20Z-
dc.date.issued2012-04-
dc.identifier.citationDistribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda. 2012, 50 (3):276-80 Med. Mycol.en_GB
dc.identifier.issn1460-2709-
dc.identifier.pmid21905950-
dc.identifier.doi10.3109/13693786.2011.604862-
dc.identifier.urihttp://hdl.handle.net/10147/222413-
dc.description.abstractOropharyngeal candidiasis remains a significant clinical problem in HIV-infected and AIDS patients in regions of Africa where anti-retroviral therapy isn't readily available. In this study we identified the yeast populations associated with oral lesions in HIV-infected patients in Southwest Uganda who were receiving treatment with nystatin and topical clotrimazole. Samples were taken from 605 patients and 316 (52%) of these yielded yeast growth following incubation on Sabouraud dextrose agar. Samples were subsequently re-plated on CHROMagar Candida medium to facilitate identification of the yeast species present. The majority (56%) of culture-positive samples yielded a mix of two or more species. Candida albicans was present in 87% (274/316) of patient samples and accounted for 87% (120/138) of single species samples. Candida glabrata, Candida tropicalis and Candida norvegensis were also found in cultures that yielded a single species. No Candida dubliniensis isolates were identified in this population.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to Medical mycology : official publication of the International Society for Human and Animal Mycologyen_GB
dc.titleDistribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda.en_GB
dc.typeArticleen
dc.contributor.departmentSchool of Allied Health Sciences, Kampala International University, Republic of Uganda.en_GB
dc.identifier.journalMedical mycology : official publication of the International Society for Human and Animal Mycologyen_GB
dc.description.provinceLeinsteren

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