Effectiveness of 2010/2011 seasonal influenza vaccine in Ireland.

2.50
Hdl Handle:
http://hdl.handle.net/10147/220513
Title:
Effectiveness of 2010/2011 seasonal influenza vaccine in Ireland.
Authors:
Barret, A S; Donnell, J O; O'Hora, A; Collins, C; Coughlan, S; Joyce, M; Moran, J; Waters, A; O'Malley, A; Domegan, L; O'Flanagan, D
Affiliation:
Health Protection Surveillance Centre, 25-27 Middle Gardiner Street, Dublin 1. asbarret@hotmail.fr
Citation:
Effectiveness of 2010/2011 seasonal influenza vaccine in Ireland. 2012, 105 (2):39-42 Ir Med J
Journal:
Irish medical journal
Issue Date:
Feb-2012
URI:
http://hdl.handle.net/10147/220513
PubMed ID:
22455236
Abstract:
We conducted a case-control study to estimate the 2010/2011 trivalent influenza vaccine effectiveness (TIVE) using the Irish general practitioners' influenza sentinel surveillance scheme. Cases were influenza-like illness (ILI) patients with laboratory-confirmed influenza. Controls were ILI patients who tested negative for influenza. Participating sentinel general practitioners (GP) collected swabs from patients presenting with ILI along with their vaccination history and other individual characteristics. The TIVE was computed as (1 - odds ratiofor vaccination) x100%. Of 60 sentinel GP practices, 22 expressed interest in participating in the study and 17 (28%) recruited at least one ILI patient. In the analysis, we included 106 cases and 85 controls. Seven controls (8.2%) and one influenza case (0.9%) had been vaccinated in 2010/2011. The estimated TIVE against any influenza subtype was 89.4% [95% CI: 13.8; 99.8%], suggesting a protective effect against GP-attended laboratory confirmed influenza. This study design could be used to monitor influenza vaccine effectiveness annually but sample size and vaccination coverage should be increased to obtain precise and adjusted estimates.
Item Type:
Article
Language:
en
MeSH:
Case-Control Studies; Humans; Influenza Vaccines; Influenza, Human; Ireland; Population Surveillance
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorBarret, A Sen_GB
dc.contributor.authorDonnell, J Oen_GB
dc.contributor.authorO'Hora, Aen_GB
dc.contributor.authorCollins, Cen_GB
dc.contributor.authorCoughlan, Sen_GB
dc.contributor.authorJoyce, Men_GB
dc.contributor.authorMoran, Jen_GB
dc.contributor.authorWaters, Aen_GB
dc.contributor.authorO'Malley, Aen_GB
dc.contributor.authorDomegan, Len_GB
dc.contributor.authorO'Flanagan, Den_GB
dc.date.accessioned2012-04-25T14:30:14Z-
dc.date.available2012-04-25T14:30:14Z-
dc.date.issued2012-02-
dc.identifier.citationEffectiveness of 2010/2011 seasonal influenza vaccine in Ireland. 2012, 105 (2):39-42 Ir Med Jen_GB
dc.identifier.issn0332-3102-
dc.identifier.pmid22455236-
dc.identifier.urihttp://hdl.handle.net/10147/220513-
dc.description.abstractWe conducted a case-control study to estimate the 2010/2011 trivalent influenza vaccine effectiveness (TIVE) using the Irish general practitioners' influenza sentinel surveillance scheme. Cases were influenza-like illness (ILI) patients with laboratory-confirmed influenza. Controls were ILI patients who tested negative for influenza. Participating sentinel general practitioners (GP) collected swabs from patients presenting with ILI along with their vaccination history and other individual characteristics. The TIVE was computed as (1 - odds ratiofor vaccination) x100%. Of 60 sentinel GP practices, 22 expressed interest in participating in the study and 17 (28%) recruited at least one ILI patient. In the analysis, we included 106 cases and 85 controls. Seven controls (8.2%) and one influenza case (0.9%) had been vaccinated in 2010/2011. The estimated TIVE against any influenza subtype was 89.4% [95% CI: 13.8; 99.8%], suggesting a protective effect against GP-attended laboratory confirmed influenza. This study design could be used to monitor influenza vaccine effectiveness annually but sample size and vaccination coverage should be increased to obtain precise and adjusted estimates.-
dc.language.isoenen
dc.rightsArchived with thanks to Irish medical journalen_GB
dc.subject.meshCase-Control Studies-
dc.subject.meshHumans-
dc.subject.meshInfluenza Vaccines-
dc.subject.meshInfluenza, Human-
dc.subject.meshIreland-
dc.subject.meshPopulation Surveillance-
dc.titleEffectiveness of 2010/2011 seasonal influenza vaccine in Ireland.en_GB
dc.typeArticleen
dc.contributor.departmentHealth Protection Surveillance Centre, 25-27 Middle Gardiner Street, Dublin 1. asbarret@hotmail.fren_GB
dc.identifier.journalIrish medical journalen_GB

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