Friedreich's Ataxia: a review from a cardiology perspective.

Hdl Handle:
http://hdl.handle.net/10147/217655
Title:
Friedreich's Ataxia: a review from a cardiology perspective.
Authors:
Bourke, T; Keane, D
Affiliation:
Cardiac Arrhythmia Service, St Vincent's University Hospital, Elm Park, Dublin, Ireland. tarabourke@hotmail.com
Citation:
Friedreich's Ataxia: a review from a cardiology perspective. 2011, 180 (4):799-805 Ir J Med Sci
Journal:
Irish journal of medical science
Issue Date:
Dec-2011
URI:
http://hdl.handle.net/10147/217655
DOI:
10.1007/s11845-011-0744-y
PubMed ID:
21822977
Abstract:
Neuromuscular disorders are not among the common causes of cardiomyopathy in the general population; however, cardiomyopathy is known to occur in several neuromuscular disorders including Friedreich's Ataxia (FA). In patients with neuromuscular disorders, concomitant cardiac involvement contributes significantly to morbidity and mortality and often leads to premature death.; An extensive literature search of Medline and Pubmed was conducted to include all published reports on cardiac involvement in FA. Secondary articles were identified from key paper reference listings.; Hypertrophic cardiomyopathy is a cardinal feature of FA; therefore all FA patients should be screened for cardiomyopathy. A cardiac examination, ECG and ECHO are advised at diagnosis, and also on the development of any cardiac symptoms. Treatment is determined by the presence of symptoms, the presence of left ventricular outflow gradient and the sudden death risk. Institution of aggressive medical therapy early in the course of the disease may help improve quality of life and provide survival benefit.
Language:
en
MeSH:
Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Chest Pain; Friedreich Ataxia; Heart Failure; Humans
ISSN:
1863-4362
Ethical Approval:
N/A

Full metadata record

DC FieldValue Language
dc.contributor.authorBourke, T-
dc.contributor.authorKeane, D-
dc.date.accessioned2012-04-04T11:16:45Z-
dc.date.available2012-04-04T11:16:45Z-
dc.date.issued2011-12-
dc.identifier.citationFriedreich's Ataxia: a review from a cardiology perspective. 2011, 180 (4):799-805 Ir J Med Sci-
dc.identifier.issn1863-4362-
dc.identifier.pmid21822977-
dc.identifier.doi10.1007/s11845-011-0744-y-
dc.identifier.urihttp://hdl.handle.net/10147/217655-
dc.description.abstractNeuromuscular disorders are not among the common causes of cardiomyopathy in the general population; however, cardiomyopathy is known to occur in several neuromuscular disorders including Friedreich's Ataxia (FA). In patients with neuromuscular disorders, concomitant cardiac involvement contributes significantly to morbidity and mortality and often leads to premature death.-
dc.description.abstractAn extensive literature search of Medline and Pubmed was conducted to include all published reports on cardiac involvement in FA. Secondary articles were identified from key paper reference listings.-
dc.description.abstractHypertrophic cardiomyopathy is a cardinal feature of FA; therefore all FA patients should be screened for cardiomyopathy. A cardiac examination, ECG and ECHO are advised at diagnosis, and also on the development of any cardiac symptoms. Treatment is determined by the presence of symptoms, the presence of left ventricular outflow gradient and the sudden death risk. Institution of aggressive medical therapy early in the course of the disease may help improve quality of life and provide survival benefit.-
dc.language.isoen-
dc.rightsArchived with thanks to Irish journal of medical scienceen_GB
dc.subject.meshArrhythmias, Cardiac-
dc.subject.meshCardiomyopathy, Hypertrophic-
dc.subject.meshChest Pain-
dc.subject.meshFriedreich Ataxia-
dc.subject.meshHeart Failure-
dc.subject.meshHumans-
dc.titleFriedreich's Ataxia: a review from a cardiology perspective.en_GB
dc.contributor.departmentCardiac Arrhythmia Service, St Vincent's University Hospital, Elm Park, Dublin, Ireland. tarabourke@hotmail.com-
dc.identifier.journalIrish journal of medical science-
dc.type.qualificationlevelN/Aen
cr.approval.ethicalN/Aen
dc.description.provinceLeinsteren
dc.description.provinceLeinster-

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