The use of bone morphogenetic protein 7 in fracture non-unions.

Hdl Handle:
http://hdl.handle.net/10147/217652
Title:
The use of bone morphogenetic protein 7 in fracture non-unions.
Authors:
O'hEireamhoin, Sven; Quinlan, John F; Rourke, Kieran O
Affiliation:
Department of Trauma and Orthopaedics, St. Vincent's University Hospital, Elm Park, Dublin, Ireland. svenerwin@hotmail.com
Citation:
The use of bone morphogenetic protein 7 in fracture non-unions. 2011, 3 (1):40-4 Orthop Surg
Journal:
Orthopaedic surgery
Issue Date:
Feb-2011
URI:
http://hdl.handle.net/10147/217652
DOI:
10.1111/j.1757-7861.2010.00119.x
PubMed ID:
22009979
Abstract:
To assess the rate of clinical and radiological union with the use of bone morphogenetic protein 7 (BMP-7) in a range of fractures.; This case series retrospectively reviews a series of 16 fracture non-unions in 13 patients. These patients were treated with the commercially available BMP-7. Time to radiological and clinical union was assessed by serial out-patient follow-up.; At nine months post-surgery in which BMP-7 was added, 12 of 16 non-unions had achieved clinical and radiographic union. Three patients required repeat grafting. The mean time to union was 5.1 ± 1.6 months after the application of BMP-7.; The use of the osteo-inductive agent, BMP-7 results in good clinical and radiological outcomes which are not restricted to tibial non-unions.
Language:
en
MeSH:
Adult; Aged; Aged, 80 and over; Bone Morphogenetic Protein 7; Drug Evaluation; Female; Femoral Fractures; Follow-Up Studies; Fracture Healing; Fractures, Ununited; Humans; Humeral Fractures; Male; Middle Aged; Retrospective Studies; Tibial Fractures; Treatment Outcome
ISSN:
1757-7861
Ethical Approval:
N/A

Full metadata record

DC FieldValue Language
dc.contributor.authorO'hEireamhoin, Sven-
dc.contributor.authorQuinlan, John F-
dc.contributor.authorRourke, Kieran O-
dc.date.accessioned2012-04-04T11:13:51Z-
dc.date.available2012-04-04T11:13:51Z-
dc.date.issued2011-02-
dc.identifier.citationThe use of bone morphogenetic protein 7 in fracture non-unions. 2011, 3 (1):40-4 Orthop Surg-
dc.identifier.issn1757-7861-
dc.identifier.pmid22009979-
dc.identifier.doi10.1111/j.1757-7861.2010.00119.x-
dc.identifier.urihttp://hdl.handle.net/10147/217652-
dc.description.abstractTo assess the rate of clinical and radiological union with the use of bone morphogenetic protein 7 (BMP-7) in a range of fractures.-
dc.description.abstractThis case series retrospectively reviews a series of 16 fracture non-unions in 13 patients. These patients were treated with the commercially available BMP-7. Time to radiological and clinical union was assessed by serial out-patient follow-up.-
dc.description.abstractAt nine months post-surgery in which BMP-7 was added, 12 of 16 non-unions had achieved clinical and radiographic union. Three patients required repeat grafting. The mean time to union was 5.1 ± 1.6 months after the application of BMP-7.-
dc.description.abstractThe use of the osteo-inductive agent, BMP-7 results in good clinical and radiological outcomes which are not restricted to tibial non-unions.-
dc.language.isoen-
dc.rightsArchived with thanks to Orthopaedic surgeryen_GB
dc.subject.meshAdult-
dc.subject.meshAged-
dc.subject.meshAged, 80 and over-
dc.subject.meshBone Morphogenetic Protein 7-
dc.subject.meshDrug Evaluation-
dc.subject.meshFemale-
dc.subject.meshFemoral Fractures-
dc.subject.meshFollow-Up Studies-
dc.subject.meshFracture Healing-
dc.subject.meshFractures, Ununited-
dc.subject.meshHumans-
dc.subject.meshHumeral Fractures-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshRetrospective Studies-
dc.subject.meshTibial Fractures-
dc.subject.meshTreatment Outcome-
dc.titleThe use of bone morphogenetic protein 7 in fracture non-unions.en_GB
dc.contributor.departmentDepartment of Trauma and Orthopaedics, St. Vincent's University Hospital, Elm Park, Dublin, Ireland. svenerwin@hotmail.com-
dc.identifier.journalOrthopaedic surgery-
dc.type.qualificationlevelN/Aen
cr.approval.ethicalN/Aen
dc.description.provinceLeinsteren
dc.description.provinceLeinster-

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