Antenatal suspicion of ischemic placental disease and coexistence of maternal and fetal placental disease: analysis of over 500 cases.
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Affiliation
Fetal Medicine Center, National Maternity Hospital, Dublin, Ireland.Issue Date
2011-12MeSH
AdultChorioamnionitis
Female
Fetal Diseases
Humans
Incidence
Ischemia
Morbidity
Placenta Diseases
Placental Circulation
Pregnancy
Pregnancy Outcome
Premature Birth
Prenatal Diagnosis
Prospective Studies
Risk Factors
Thrombosis
Young Adult
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Antenatal suspicion of ischemic placental disease and coexistence of maternal and fetal placental disease: analysis of over 500 cases. 2011, 205 (6):576.e1-6 Am. J. Obstet. Gynecol.Journal
American journal of obstetrics and gynecologyDOI
10.1016/j.ajog.2011.06.061PubMed ID
21903194Abstract
To investigate the antenatal suspicion of placental disease and the coexistence of maternal and fetal placental ischemic disease.A prospective cohort study on normally formed singleton infants from 2000 to 2008 inclusive with placental ischemic disease.
Uteroplacental ischemia or fetoplacental thrombotic vasculopathy was identified in 511 of 74,857 births (7/1000 births). Four hundred fifty-nine cases met the inclusion criteria. Maternal and fetal placental vascular disease coexisted in 9.2% (n = 42) of cases. Placental ischemic disease was suspected antenatally in 70% (324/459). Maternal placental disease occurred in 40% (184/459) and 30% (140/459) had fetal pathology. The perinatal mortality rate was 12.7/1000. Antenatal suspicion of placental disease led to increased obstetric intervention and delivery of small-for-gestational age infants.
Maternal and fetoplacental vascular disease coexisted in 9.2%. Placental disease was suspected antenatally in 70% of cases and was associated with increased rates of obstetric intervention.
Language
enISSN
1097-6868Ethical Approval
N/Aae974a485f413a2113503eed53cd6c53
10.1016/j.ajog.2011.06.061