Ultrasonically detectable cerebellar haemorrhage in preterm infants.

Hdl Handle:
http://hdl.handle.net/10147/217181
Title:
Ultrasonically detectable cerebellar haemorrhage in preterm infants.
Authors:
McCarthy, Lisa Kenyon; Donoghue, V; Murphy, J F A
Affiliation:
Department of Neonatology, The National Maternity Hospital, Dublin, Ireland. lmccarthy@nmh.ie
Citation:
Ultrasonically detectable cerebellar haemorrhage in preterm infants. 2011, 96 (4):F281-5 Arch. Dis. Child. Fetal Neonatal Ed.
Journal:
Archives of disease in childhood. Fetal and neonatal edition
Issue Date:
Jul-2011
URI:
http://hdl.handle.net/10147/217181
DOI:
10.1136/adc.2010.183889
PubMed ID:
21252199
Abstract:
To determine the frequency and pattern of cerebellar haemorrhage (CBH) on routine cranial ultrasound (cUS) imaging in infants of ≤32 weeks gestation, and to investigate how extremely preterm infants with CBH differ from those with severe intraventricular haemorrhage (IVH).; 672 infants of ≤32 weeks gestation were prospectively examined for CBH on serial cUS imaging. In a separate case--control analysis, the clinical features, ultrasound findings and outcome of preterm infants with CBH were compared to those of infants with isolated severe IVH (grade III-IV).; Nine cases of CBH were identified among 53 infants with severe IVH. The incidence of CBH in infants of ≤32 weeks gestation was 1.3%. Five infants had bilateral CBH involving both hemispheres, three had unilateral left sided CBH and one had a right hemispheric lesion. Infants with CBH were male, significantly more preterm (24.4 vs 27.0 weeks) and of lower birth weight (692 g vs 979 g). Vaginal births predominated in the CBH group (89% vs 50%). The median time to identification of haemorrhage for both groups was 3 days. Mortality in the CBH group was 100% (9/9) compared to 43% (19/44) in the severe IVH group.; Extensive CBH in preterm infants is rare and devastating. It appears to be confined to very preterm, extremely low birthweight infants and may have a male predominance. The co-existence of severe IVH and extensive CBH on routine cot-side cUS in the early neonatal period is an ominous finding.
Language:
en
MeSH:
Birth Weight; Case-Control Studies; Cerebral Hemorrhage; Female; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Male; Prognosis; Prospective Studies; Sex Factors
ISSN:
1468-2052
Ethical Approval:
N/A

Full metadata record

DC FieldValue Language
dc.contributor.authorMcCarthy, Lisa Kenyon-
dc.contributor.authorDonoghue, V-
dc.contributor.authorMurphy, J F A-
dc.date.accessioned2012-03-30T13:52:05Z-
dc.date.available2012-03-30T13:52:05Z-
dc.date.issued2011-07-
dc.identifier.citationUltrasonically detectable cerebellar haemorrhage in preterm infants. 2011, 96 (4):F281-5 Arch. Dis. Child. Fetal Neonatal Ed.-
dc.identifier.issn1468-2052-
dc.identifier.pmid21252199-
dc.identifier.doi10.1136/adc.2010.183889-
dc.identifier.urihttp://hdl.handle.net/10147/217181-
dc.description.abstractTo determine the frequency and pattern of cerebellar haemorrhage (CBH) on routine cranial ultrasound (cUS) imaging in infants of ≤32 weeks gestation, and to investigate how extremely preterm infants with CBH differ from those with severe intraventricular haemorrhage (IVH).-
dc.description.abstract672 infants of ≤32 weeks gestation were prospectively examined for CBH on serial cUS imaging. In a separate case--control analysis, the clinical features, ultrasound findings and outcome of preterm infants with CBH were compared to those of infants with isolated severe IVH (grade III-IV).-
dc.description.abstractNine cases of CBH were identified among 53 infants with severe IVH. The incidence of CBH in infants of ≤32 weeks gestation was 1.3%. Five infants had bilateral CBH involving both hemispheres, three had unilateral left sided CBH and one had a right hemispheric lesion. Infants with CBH were male, significantly more preterm (24.4 vs 27.0 weeks) and of lower birth weight (692 g vs 979 g). Vaginal births predominated in the CBH group (89% vs 50%). The median time to identification of haemorrhage for both groups was 3 days. Mortality in the CBH group was 100% (9/9) compared to 43% (19/44) in the severe IVH group.-
dc.description.abstractExtensive CBH in preterm infants is rare and devastating. It appears to be confined to very preterm, extremely low birthweight infants and may have a male predominance. The co-existence of severe IVH and extensive CBH on routine cot-side cUS in the early neonatal period is an ominous finding.-
dc.language.isoen-
dc.rightsArchived with thanks to Archives of disease in childhood. Fetal and neonatal editionen_GB
dc.subject.meshBirth Weight-
dc.subject.meshCase-Control Studies-
dc.subject.meshCerebral Hemorrhage-
dc.subject.meshFemale-
dc.subject.meshGestational Age-
dc.subject.meshHumans-
dc.subject.meshInfant, Low Birth Weight-
dc.subject.meshInfant, Newborn-
dc.subject.meshInfant, Premature-
dc.subject.meshInfant, Premature, Diseases-
dc.subject.meshIntensive Care Units, Neonatal-
dc.subject.meshMale-
dc.subject.meshPrognosis-
dc.subject.meshProspective Studies-
dc.subject.meshSex Factors-
dc.titleUltrasonically detectable cerebellar haemorrhage in preterm infants.en_GB
dc.contributor.departmentDepartment of Neonatology, The National Maternity Hospital, Dublin, Ireland. lmccarthy@nmh.ie-
dc.identifier.journalArchives of disease in childhood. Fetal and neonatal edition-
dc.type.qualificationlevelN/Aen
cr.approval.ethicalN/Aen
dc.description.provinceLeinsteren
dc.description.provinceLeinster-

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