STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria.

Hdl Handle:
http://hdl.handle.net/10147/209278
Title:
STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria.
Authors:
Gallagher, Paul; O'Mahony, Denis
Affiliation:
Department of Geriatric Medicine, Cork University Hospital, Wilton, Cork,, Ireland.
Citation:
Age Ageing. 2008 Nov;37(6):673-9. Epub 2008 Oct 1.
Journal:
Age and ageing
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209278
DOI:
10.1093/ageing/afn197
PubMed ID:
18829684
Abstract:
Introduction: STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions) is a new, systems-defined medicine review tool. We compared the performance of STOPP to that of established Beers' criteria in detecting potentially inappropriate medicines (PIMs) and related adverse drug events (ADEs) in older patients presenting for hospital admission. METHODS: we prospectively studied 715 consecutive acute admissions to a university teaching hospital. Diagnoses, reason for admission and concurrent medications were recorded. STOPP and Beers' criteria were applied. PIMs with clear causal connection or contribution to the principal reason for admission were determined. RESULTS: median patient age (interquartile range) was 77 (72-82) years. Median number of prescription medicines was 6 (range 0-21). STOPP identified 336 PIMs affecting 247 patients (35%), of whom one-third (n = 82) presented with an associated ADE. Beers' criteria identified 226 PIMs affecting 177 patients (25%), of whom 43 presented with an associated ADE. STOPP-related PIMs contributed to 11.5% of all admissions. Beers' criteria-related PIMs contributed to significantly fewer admissions (6%). CONCLUSION: STOPP criteria identified a significantly higher proportion of patients requiring hospitalisation as a result of PIM-related adverse events than Beers' criteria. This finding has significant implications for hospital geriatric practice.
Language:
eng
MeSH:
Acute Disease; Admitting Department, Hospital/statistics & numerical data; Aged; Aged, 80 and over; Drug Interactions; Female; Hospitals, University/statistics & numerical data; Humans; Male; Mass Screening/*instrumentation; Medical Records/*statistics & numerical data; Prescription Drugs/*adverse effects/standards/*therapeutic use; Prospective Studies; Sensitivity and Specificity
ISSN:
1468-2834 (Electronic); 0002-0729 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorGallagher, Paulen_GB
dc.contributor.authorO'Mahony, Denisen_GB
dc.date.accessioned2012-02-03T15:17:00Z-
dc.date.available2012-02-03T15:17:00Z-
dc.date.issued2012-02-03T15:17:00Z-
dc.identifier.citationAge Ageing. 2008 Nov;37(6):673-9. Epub 2008 Oct 1.en_GB
dc.identifier.issn1468-2834 (Electronic)en_GB
dc.identifier.issn0002-0729 (Linking)en_GB
dc.identifier.pmid18829684en_GB
dc.identifier.doi10.1093/ageing/afn197en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209278-
dc.description.abstractIntroduction: STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions) is a new, systems-defined medicine review tool. We compared the performance of STOPP to that of established Beers' criteria in detecting potentially inappropriate medicines (PIMs) and related adverse drug events (ADEs) in older patients presenting for hospital admission. METHODS: we prospectively studied 715 consecutive acute admissions to a university teaching hospital. Diagnoses, reason for admission and concurrent medications were recorded. STOPP and Beers' criteria were applied. PIMs with clear causal connection or contribution to the principal reason for admission were determined. RESULTS: median patient age (interquartile range) was 77 (72-82) years. Median number of prescription medicines was 6 (range 0-21). STOPP identified 336 PIMs affecting 247 patients (35%), of whom one-third (n = 82) presented with an associated ADE. Beers' criteria identified 226 PIMs affecting 177 patients (25%), of whom 43 presented with an associated ADE. STOPP-related PIMs contributed to 11.5% of all admissions. Beers' criteria-related PIMs contributed to significantly fewer admissions (6%). CONCLUSION: STOPP criteria identified a significantly higher proportion of patients requiring hospitalisation as a result of PIM-related adverse events than Beers' criteria. This finding has significant implications for hospital geriatric practice.en_GB
dc.language.isoengen_GB
dc.subject.meshAcute Diseaseen_GB
dc.subject.meshAdmitting Department, Hospital/statistics & numerical dataen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshDrug Interactionsen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHospitals, University/statistics & numerical dataen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMass Screening/*instrumentationen_GB
dc.subject.meshMedical Records/*statistics & numerical dataen_GB
dc.subject.meshPrescription Drugs/*adverse effects/standards/*therapeutic useen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshSensitivity and Specificityen_GB
dc.titleSTOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria.en_GB
dc.contributor.departmentDepartment of Geriatric Medicine, Cork University Hospital, Wilton, Cork,, Ireland.en_GB
dc.identifier.journalAge and ageingen_GB
dc.description.provinceMunster-

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