Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.

Hdl Handle:
http://hdl.handle.net/10147/209212
Title:
Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.
Authors:
Cotter, T P; Kealy, N P; Duggan, P F; Curtain, A; Bredin, C P
Affiliation:
Cork University Hospital, Ireland.
Citation:
Respir Med. 1997 Apr;91(4):237-9.
Journal:
Respiratory medicine
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209212
PubMed ID:
9156148
Abstract:
A case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.
Language:
eng
MeSH:
Adult; Disorders of Sex Development/complications/genetics; Dysgerminoma/enzymology/*secondary/therapy; Female; Humans; Lymphatic Metastasis; Male; Ovarian Neoplasms/*pathology; Peptidyl-Dipeptidase A/*blood; Tumor Markers, Biological/*blood
ISSN:
0954-6111 (Print); 0954-6111 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorCotter, T Pen_GB
dc.contributor.authorKealy, N Pen_GB
dc.contributor.authorDuggan, P Fen_GB
dc.contributor.authorCurtain, Aen_GB
dc.contributor.authorBredin, C Pen_GB
dc.date.accessioned2012-02-03T15:15:13Z-
dc.date.available2012-02-03T15:15:13Z-
dc.date.issued2012-02-03T15:15:13Z-
dc.identifier.citationRespir Med. 1997 Apr;91(4):237-9.en_GB
dc.identifier.issn0954-6111 (Print)en_GB
dc.identifier.issn0954-6111 (Linking)en_GB
dc.identifier.pmid9156148en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209212-
dc.description.abstractA case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshDisorders of Sex Development/complications/geneticsen_GB
dc.subject.meshDysgerminoma/enzymology/*secondary/therapyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLymphatic Metastasisen_GB
dc.subject.meshMaleen_GB
dc.subject.meshOvarian Neoplasms/*pathologyen_GB
dc.subject.meshPeptidyl-Dipeptidase A/*blooden_GB
dc.subject.meshTumor Markers, Biological/*blooden_GB
dc.titleElevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.en_GB
dc.contributor.departmentCork University Hospital, Ireland.en_GB
dc.identifier.journalRespiratory medicineen_GB
dc.description.provinceMunster-

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