Hdl Handle:
http://hdl.handle.net/10147/209181
Title:
Immunonutrition: the role of taurine.
Authors:
Redmond, H P; Stapleton, P P; Neary, P; Bouchier-Hayes, D
Affiliation:
Department of Surgery, Cork University Hospital, Ireland.
Citation:
Nutrition. 1998 Jul-Aug;14(7-8):599-604.
Journal:
Nutrition (Burbank, Los Angeles County, Calif.)
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209181
PubMed ID:
9684263
Abstract:
Taurine is a sulfonated beta amino acid derived from methionine and cysteine metabolism. It is present in high concentrations in most tissues and in particular in proinflammatory cells such as polymorphonuclear phagocytes. Initial investigation into the multifaceted properties of this non-toxic physiologic amino acid revealed a link between retinal dysfunction and dietary deficiency. Since then a role for this amino acid has been found in membrane stabilization, bile salt formation, antioxidation, calcium homeostasis, growth modulation, and osmoregulation. Our own group has demonstrated a key role for taurine in modulation of apoptosis in a variety of cell types. This review summarizes our current knowledge of taurine in nutrition, host proinflammatory cell homeostasis, therapeutic applications, and its potential immunoregulatory properties. It is our belief that taurine, similar to arginine and glutamine, is now more than worthy of critical clinical analysis.
Language:
eng
MeSH:
Homeostasis; Humans; *Immunity; *Nutritional Physiological Phenomena; Postoperative Period; Reperfusion Injury; Sepsis; Taurine/*physiology/therapeutic use
ISSN:
0899-9007 (Print); 0899-9007 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorRedmond, H Pen_GB
dc.contributor.authorStapleton, P Pen_GB
dc.contributor.authorNeary, Pen_GB
dc.contributor.authorBouchier-Hayes, Den_GB
dc.date.accessioned2012-02-03T15:14:25Z-
dc.date.available2012-02-03T15:14:25Z-
dc.date.issued2012-02-03T15:14:25Z-
dc.identifier.citationNutrition. 1998 Jul-Aug;14(7-8):599-604.en_GB
dc.identifier.issn0899-9007 (Print)en_GB
dc.identifier.issn0899-9007 (Linking)en_GB
dc.identifier.pmid9684263en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209181-
dc.description.abstractTaurine is a sulfonated beta amino acid derived from methionine and cysteine metabolism. It is present in high concentrations in most tissues and in particular in proinflammatory cells such as polymorphonuclear phagocytes. Initial investigation into the multifaceted properties of this non-toxic physiologic amino acid revealed a link between retinal dysfunction and dietary deficiency. Since then a role for this amino acid has been found in membrane stabilization, bile salt formation, antioxidation, calcium homeostasis, growth modulation, and osmoregulation. Our own group has demonstrated a key role for taurine in modulation of apoptosis in a variety of cell types. This review summarizes our current knowledge of taurine in nutrition, host proinflammatory cell homeostasis, therapeutic applications, and its potential immunoregulatory properties. It is our belief that taurine, similar to arginine and glutamine, is now more than worthy of critical clinical analysis.en_GB
dc.language.isoengen_GB
dc.subject.meshHomeostasisen_GB
dc.subject.meshHumansen_GB
dc.subject.mesh*Immunityen_GB
dc.subject.mesh*Nutritional Physiological Phenomenaen_GB
dc.subject.meshPostoperative Perioden_GB
dc.subject.meshReperfusion Injuryen_GB
dc.subject.meshSepsisen_GB
dc.subject.meshTaurine/*physiology/therapeutic useen_GB
dc.titleImmunonutrition: the role of taurine.en_GB
dc.contributor.departmentDepartment of Surgery, Cork University Hospital, Ireland.en_GB
dc.identifier.journalNutrition (Burbank, Los Angeles County, Calif.)en_GB
dc.description.provinceMunster-

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