New lessons: Classic treatments in convulsive status epilepticus.

Hdl Handle:
http://hdl.handle.net/10147/209175
Title:
New lessons: Classic treatments in convulsive status epilepticus.
Authors:
Renganathan, R; Conlon, N; Sweeney, B
Affiliation:
Department of Neurology, Cork University Hospital, Cork. howrurenga@yahoo.com
Citation:
Ir Med J. 2007 Nov-Dec;100(10):618-20.
Journal:
Irish medical journal
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209175
PubMed ID:
18277730
Abstract:
Convulsive status epilepticus is a relatively common life-threatening illness requiring prompt intervention. There has been much debate about the appropriate protocol for management of convulsive status epilepticus. Published data on the management of this condition in Ireland is limited. Our aim was to establish if there was a structured, evidence-based or consensus-based protocol being implemented in the management of status epilepticus in our centre. We retrospectively audited all charts with a diagnosis of 'Status Epilepticus' admitted to our hospital from January 1998 to December 2002. A total of 95 episodes of convulsive status epilepticus were recorded. 34 charts were reviewed. Benzodiazepines were the drug class of first choice in 96% of patients. However, the doses of benzodiazepines used varied widely. The most frequent dose of phenytoin used was 1 gram. No one received continuous EEG monitoring during treatment of refractory status epilepticus. Overall mortality was 18%. The results of this study show that there is no consistent protocol was being followed for the management of convulsive status epilepticus in our centre. The drugs of first choice varied between diazepam and lorazepam in most cases. Although phenytoin was used as second line drug, the dose used was frequently suboptimal. We have developed a protocol for the management for convulsive status in our centre.
Language:
eng
MeSH:
Adult; Aged; Aged, 80 and over; Anticonvulsants/*therapeutic use; Benzodiazepines/therapeutic use; Clinical Protocols; Diazepam/therapeutic use; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Male; Middle Aged; Phenytoin/therapeutic use; Retrospective Studies; Status Epilepticus/*drug therapy
ISSN:
0332-3102 (Print); 0332-3102 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorRenganathan, Ren_GB
dc.contributor.authorConlon, Nen_GB
dc.contributor.authorSweeney, Ben_GB
dc.date.accessioned2012-02-03T15:14:15Z-
dc.date.available2012-02-03T15:14:15Z-
dc.date.issued2012-02-03T15:14:15Z-
dc.identifier.citationIr Med J. 2007 Nov-Dec;100(10):618-20.en_GB
dc.identifier.issn0332-3102 (Print)en_GB
dc.identifier.issn0332-3102 (Linking)en_GB
dc.identifier.pmid18277730en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209175-
dc.description.abstractConvulsive status epilepticus is a relatively common life-threatening illness requiring prompt intervention. There has been much debate about the appropriate protocol for management of convulsive status epilepticus. Published data on the management of this condition in Ireland is limited. Our aim was to establish if there was a structured, evidence-based or consensus-based protocol being implemented in the management of status epilepticus in our centre. We retrospectively audited all charts with a diagnosis of 'Status Epilepticus' admitted to our hospital from January 1998 to December 2002. A total of 95 episodes of convulsive status epilepticus were recorded. 34 charts were reviewed. Benzodiazepines were the drug class of first choice in 96% of patients. However, the doses of benzodiazepines used varied widely. The most frequent dose of phenytoin used was 1 gram. No one received continuous EEG monitoring during treatment of refractory status epilepticus. Overall mortality was 18%. The results of this study show that there is no consistent protocol was being followed for the management of convulsive status epilepticus in our centre. The drugs of first choice varied between diazepam and lorazepam in most cases. Although phenytoin was used as second line drug, the dose used was frequently suboptimal. We have developed a protocol for the management for convulsive status in our centre.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnticonvulsants/*therapeutic useen_GB
dc.subject.meshBenzodiazepines/therapeutic useen_GB
dc.subject.meshClinical Protocolsen_GB
dc.subject.meshDiazepam/therapeutic useen_GB
dc.subject.meshDose-Response Relationship, Drugen_GB
dc.subject.meshElectroencephalographyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPhenytoin/therapeutic useen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshStatus Epilepticus/*drug therapyen_GB
dc.titleNew lessons: Classic treatments in convulsive status epilepticus.en_GB
dc.contributor.departmentDepartment of Neurology, Cork University Hospital, Cork. howrurenga@yahoo.comen_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceMunster-

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