Visual and anatomical success with short-term macular tamponade and autologous platelet concentrate.

Hdl Handle:
http://hdl.handle.net/10147/209114
Title:
Visual and anatomical success with short-term macular tamponade and autologous platelet concentrate.
Authors:
Mulhern, M G; Cullinane, A; Cleary, P E
Affiliation:
National University of Ireland Cork, Department of Ophthalmology, Cork University, Hospital, Ireland.
Citation:
Graefes Arch Clin Exp Ophthalmol. 2000 Jul;238(7):577-83.
Journal:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von, Graefes Archiv fur klinische und experimentelle Ophthalmologie
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209114
PubMed ID:
10955659
Abstract:
BACKGROUND: This study aimed to determine whether, in eyes treated for macular hole by vitrectomy and autologous platelet injection, short-term tamponade with SF6 gas was as effective as longer tamponade with C3F8 gas. METHODS: Patients in group 1 (n=31) had vitrectomy, injection of platelet concentrate, and 16% C3F8 gas/air exchange. Patients in group 2 (n=31) were similarly treated, except that 23% SF6 gas was used. Group 1 patients were required to posture prone for 2-4 weeks, group 2 for 6 days. RESULTS: All patients had 3 months' follow-up. Postoperatively, visual acuity improved faster in group 2. However, the final mean improvement in logMAR acuity was similar in both groups. Intraocular pressure (IOP) spikes occurred in 12 patients in group 2 and in 17 patients in group 1. Posterior subcapsular cataract (PSCC) occurred in 55% of cases in group 1 and in just 37% in group 2. The rate of anatomical success in group 1 was 96.7%, and in group 2, 93.5% (P=1.0). CONCLUSIONS: The combination of SF6 gas, platelet concentrate, and short-term prone posturing gave a degree of anatomical and visual success comparable to that of the group which had longer tamponade. Although no differences were statistically significant, several trends did emerge; in group 2, patients recovered visual acuity faster, had fewer IOP spikes, and there were fewer cases of PSCC formation.
Language:
eng
MeSH:
Aged; *Blood Platelets; Female; Fluorescein Angiography; Fluorocarbons/*therapeutic use; Fundus Oculi; Humans; Injections; Male; Prospective Studies; Retinal Perforations/pathology/physiopathology/*therapy; Sulfur Hexafluoride/*therapeutic use; Time Factors; Treatment Outcome; Visual Acuity/*physiology; Vitrectomy/methods; Vitreous Body
ISSN:
0721-832X (Print); 0721-832X (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorMulhern, M Gen_GB
dc.contributor.authorCullinane, Aen_GB
dc.contributor.authorCleary, P Een_GB
dc.date.accessioned2012-02-03T15:12:38Z-
dc.date.available2012-02-03T15:12:38Z-
dc.date.issued2012-02-03T15:12:38Z-
dc.identifier.citationGraefes Arch Clin Exp Ophthalmol. 2000 Jul;238(7):577-83.en_GB
dc.identifier.issn0721-832X (Print)en_GB
dc.identifier.issn0721-832X (Linking)en_GB
dc.identifier.pmid10955659en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209114-
dc.description.abstractBACKGROUND: This study aimed to determine whether, in eyes treated for macular hole by vitrectomy and autologous platelet injection, short-term tamponade with SF6 gas was as effective as longer tamponade with C3F8 gas. METHODS: Patients in group 1 (n=31) had vitrectomy, injection of platelet concentrate, and 16% C3F8 gas/air exchange. Patients in group 2 (n=31) were similarly treated, except that 23% SF6 gas was used. Group 1 patients were required to posture prone for 2-4 weeks, group 2 for 6 days. RESULTS: All patients had 3 months' follow-up. Postoperatively, visual acuity improved faster in group 2. However, the final mean improvement in logMAR acuity was similar in both groups. Intraocular pressure (IOP) spikes occurred in 12 patients in group 2 and in 17 patients in group 1. Posterior subcapsular cataract (PSCC) occurred in 55% of cases in group 1 and in just 37% in group 2. The rate of anatomical success in group 1 was 96.7%, and in group 2, 93.5% (P=1.0). CONCLUSIONS: The combination of SF6 gas, platelet concentrate, and short-term prone posturing gave a degree of anatomical and visual success comparable to that of the group which had longer tamponade. Although no differences were statistically significant, several trends did emerge; in group 2, patients recovered visual acuity faster, had fewer IOP spikes, and there were fewer cases of PSCC formation.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.mesh*Blood Plateletsen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFluorescein Angiographyen_GB
dc.subject.meshFluorocarbons/*therapeutic useen_GB
dc.subject.meshFundus Oculien_GB
dc.subject.meshHumansen_GB
dc.subject.meshInjectionsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshRetinal Perforations/pathology/physiopathology/*therapyen_GB
dc.subject.meshSulfur Hexafluoride/*therapeutic useen_GB
dc.subject.meshTime Factorsen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshVisual Acuity/*physiologyen_GB
dc.subject.meshVitrectomy/methodsen_GB
dc.subject.meshVitreous Bodyen_GB
dc.titleVisual and anatomical success with short-term macular tamponade and autologous platelet concentrate.en_GB
dc.contributor.departmentNational University of Ireland Cork, Department of Ophthalmology, Cork University, Hospital, Ireland.en_GB
dc.identifier.journalGraefe's archive for clinical and experimental ophthalmology = Albrecht von, Graefes Archiv fur klinische und experimentelle Ophthalmologieen_GB
dc.description.provinceMunster-
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