Premature hair greying may predict reduced bone mineral density in Graves' disease.

Hdl Handle:
http://hdl.handle.net/10147/209069
Title:
Premature hair greying may predict reduced bone mineral density in Graves' disease.
Authors:
Leary, A C; Grealy, G; Higgins, T M; Buckley, N; Barry, D G; Ferriss, J B
Affiliation:
Department of Medicine, Cork University Hospital and University College Cork,, Ireland.
Citation:
Ir J Med Sci. 2001 Apr-Jun;170(2):117-9.
Journal:
Irish journal of medical science
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209069
PubMed ID:
11491046
Abstract:
BACKGROUND: Premature hair greying has been associated with low bone mineral density (BMD), and it may be more frequent in Graves' disease. AIMS: To determine whether premature greying is associated with reduced BMD in women with Graves' disease and in control women, and to examine whether premature greying is more common in Graves' disease. METHODS: Premature greying (> 50% grey by 40 years) and BMD were determined in 44 women with a history of Graves' disease and 133 female controls referred for routine BMD measurement. Exclusion criteria included diseases or drugs known to affect BMD. RESULTS: Mean Z and T scores at the lumbar spine were significantly lower (P < 0.04) in subjects with premature greying than in those not prematurely grey among women with Graves' disease, but not among control women. Multiple regression confirmed this difference between Graves' and control women (P = 0.041). There were no differences at other measurement sites. Of Graves' patients, 36% were prematurely grey compared with 25% of control women (P = 0.14). CONCLUSION: Premature greying may be a weak marker for reduced BMD in women with a history of Graves' disease, but it is not a marker in normal women.
Language:
eng
MeSH:
Adult; Age Factors; Aged; Aged, 80 and over; *Bone Density; Case-Control Studies; Chi-Square Distribution; Female; Graves Disease/*physiopathology; *Hair Color; Humans; Middle Aged; Multivariate Analysis; Regression Analysis
ISSN:
0021-1265 (Print); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorLeary, A Cen_GB
dc.contributor.authorGrealy, Gen_GB
dc.contributor.authorHiggins, T Men_GB
dc.contributor.authorBuckley, Nen_GB
dc.contributor.authorBarry, D Gen_GB
dc.contributor.authorFerriss, J Ben_GB
dc.date.accessioned2012-02-03T15:11:26Z-
dc.date.available2012-02-03T15:11:26Z-
dc.date.issued2012-02-03T15:11:26Z-
dc.identifier.citationIr J Med Sci. 2001 Apr-Jun;170(2):117-9.en_GB
dc.identifier.issn0021-1265 (Print)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid11491046en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209069-
dc.description.abstractBACKGROUND: Premature hair greying has been associated with low bone mineral density (BMD), and it may be more frequent in Graves' disease. AIMS: To determine whether premature greying is associated with reduced BMD in women with Graves' disease and in control women, and to examine whether premature greying is more common in Graves' disease. METHODS: Premature greying (> 50% grey by 40 years) and BMD were determined in 44 women with a history of Graves' disease and 133 female controls referred for routine BMD measurement. Exclusion criteria included diseases or drugs known to affect BMD. RESULTS: Mean Z and T scores at the lumbar spine were significantly lower (P < 0.04) in subjects with premature greying than in those not prematurely grey among women with Graves' disease, but not among control women. Multiple regression confirmed this difference between Graves' and control women (P = 0.041). There were no differences at other measurement sites. Of Graves' patients, 36% were prematurely grey compared with 25% of control women (P = 0.14). CONCLUSION: Premature greying may be a weak marker for reduced BMD in women with a history of Graves' disease, but it is not a marker in normal women.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAge Factorsen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.mesh*Bone Densityen_GB
dc.subject.meshCase-Control Studiesen_GB
dc.subject.meshChi-Square Distributionen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshGraves Disease/*physiopathologyen_GB
dc.subject.mesh*Hair Coloren_GB
dc.subject.meshHumansen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshMultivariate Analysisen_GB
dc.subject.meshRegression Analysisen_GB
dc.titlePremature hair greying may predict reduced bone mineral density in Graves' disease.en_GB
dc.contributor.departmentDepartment of Medicine, Cork University Hospital and University College Cork,, Ireland.en_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceMunster-

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