Amyotrophic lateral sclerosis associated with pregnancy.

Hdl Handle:
http://hdl.handle.net/10147/209051
Title:
Amyotrophic lateral sclerosis associated with pregnancy.
Authors:
Tyagi, A; Sweeney, B J; Connolly, S
Affiliation:
Department of Neurology, Cork University Hospital, Wilton, Cork, Ireland., atyagi@gofree.indigo.ie
Citation:
Neurol India. 2001 Dec;49(4):413-4.
Journal:
Neurology India
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209051
PubMed ID:
11799421
Abstract:
Amyotrophic lateral sclerosis (ALS) is the most common, progressive motor neurone disease but is rare in the obstetric population. Only 4 cases have been described in the English literature since 1975. We describe a 29 year old woman who presented with ataxia, lower limb weakness and dysarthria 4 weeks after the birth of her first child. The symptoms had onset during the pregnancy but had not been considered remarkable. There were clinical features of upper and lower motor neurone involvement without any sensory loss. MRI of brain and spine was normal. CSF analysis was negative. EMG studies confirmed the presence of widespread anterior horn cell dysfunction compatible with ALS. The patient was commenced on Riluzole and has progressed clinically, at 12 months post diagnosis.
Language:
eng
MeSH:
Adult; Amyotrophic Lateral Sclerosis/*diagnosis/drug therapy/*physiopathology; Electromyography; Female; Humans; Magnetic Resonance Imaging; Neuroprotective Agents/therapeutic use; Pregnancy; Pregnancy Complications/*diagnosis/drug therapy/*physiopathology; Riluzole/therapeutic use
ISSN:
0028-3886 (Print); 0028-3886 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorTyagi, Aen_GB
dc.contributor.authorSweeney, B Jen_GB
dc.contributor.authorConnolly, Sen_GB
dc.date.accessioned2012-02-03T15:10:56Z-
dc.date.available2012-02-03T15:10:56Z-
dc.date.issued2012-02-03T15:10:56Z-
dc.identifier.citationNeurol India. 2001 Dec;49(4):413-4.en_GB
dc.identifier.issn0028-3886 (Print)en_GB
dc.identifier.issn0028-3886 (Linking)en_GB
dc.identifier.pmid11799421en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209051-
dc.description.abstractAmyotrophic lateral sclerosis (ALS) is the most common, progressive motor neurone disease but is rare in the obstetric population. Only 4 cases have been described in the English literature since 1975. We describe a 29 year old woman who presented with ataxia, lower limb weakness and dysarthria 4 weeks after the birth of her first child. The symptoms had onset during the pregnancy but had not been considered remarkable. There were clinical features of upper and lower motor neurone involvement without any sensory loss. MRI of brain and spine was normal. CSF analysis was negative. EMG studies confirmed the presence of widespread anterior horn cell dysfunction compatible with ALS. The patient was commenced on Riluzole and has progressed clinically, at 12 months post diagnosis.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAmyotrophic Lateral Sclerosis/*diagnosis/drug therapy/*physiopathologyen_GB
dc.subject.meshElectromyographyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMagnetic Resonance Imagingen_GB
dc.subject.meshNeuroprotective Agents/therapeutic useen_GB
dc.subject.meshPregnancyen_GB
dc.subject.meshPregnancy Complications/*diagnosis/drug therapy/*physiopathologyen_GB
dc.subject.meshRiluzole/therapeutic useen_GB
dc.titleAmyotrophic lateral sclerosis associated with pregnancy.en_GB
dc.contributor.departmentDepartment of Neurology, Cork University Hospital, Wilton, Cork, Ireland., atyagi@gofree.indigo.ieen_GB
dc.identifier.journalNeurology Indiaen_GB
dc.description.provinceMunster-

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