Postoperative changes in visual evoked potentials and cognitive function tests following sevoflurane anaesthesia.

Hdl Handle:
http://hdl.handle.net/10147/209047
Title:
Postoperative changes in visual evoked potentials and cognitive function tests following sevoflurane anaesthesia.
Authors:
Iohom, G; Collins, I; Murphy, D; Awad, I; O'Connor, G; McCarthy, N; Shorten, G
Affiliation:
Department of Anaesthesia and Intensive Care Medicine, Cork University Hospital, and National University of Ireland, Republic of Ireland.
Citation:
Br J Anaesth. 2001 Dec;87(6):855-9.
Journal:
British journal of anaesthesia
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209047
PubMed ID:
11878686
Abstract:
We tested the hypothesis that minor disturbance of the visual pathway persists following general anaesthesia even when clinical discharge criteria are met. To test this, we measured visual evoked potentials (VEPs) in 13 ASA I or II patients who did not receive any pre-anaesthetic medication and underwent sevoflurane anaesthesia. VEPs were recorded on four occasions, before anaesthesia and at 30, 60, and 90 min after emergence from anaesthesia. Patients completed visual analogue scales (VAS) for sedation and anxiety, a Trieger Dot Test (TDT) and a Digit Symbol Substitution Test (DSST) immediately before each VEP recording. These results were compared using Student's t-test. P<0.05 was considered significant. VEP latency was prolonged (P<0.001) and amplitude diminished (P<0.05) at 30, 60, and 90 min after emergence from anaesthesia, when VAS scores for sedation and anxiety, TDT, and DSST had returned to pre-anaesthetic levels.
Language:
eng
MeSH:
Adolescent; Adult; Anesthetics, Inhalation/*pharmacology; Cognition/*drug effects; Evoked Potentials, Visual/*drug effects; Female; Humans; Male; Methyl Ethers/*pharmacology; Middle Aged; Postoperative Period; Prospective Studies; Psychometrics; Psychomotor Performance/drug effects; Reaction Time/drug effects
ISSN:
0007-0912 (Print); 0007-0912 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorIohom, Gen_GB
dc.contributor.authorCollins, Ien_GB
dc.contributor.authorMurphy, Den_GB
dc.contributor.authorAwad, Ien_GB
dc.contributor.authorO'Connor, Gen_GB
dc.contributor.authorMcCarthy, Nen_GB
dc.contributor.authorShorten, Gen_GB
dc.date.accessioned2012-02-03T15:10:50Z-
dc.date.available2012-02-03T15:10:50Z-
dc.date.issued2012-02-03T15:10:50Z-
dc.identifier.citationBr J Anaesth. 2001 Dec;87(6):855-9.en_GB
dc.identifier.issn0007-0912 (Print)en_GB
dc.identifier.issn0007-0912 (Linking)en_GB
dc.identifier.pmid11878686en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209047-
dc.description.abstractWe tested the hypothesis that minor disturbance of the visual pathway persists following general anaesthesia even when clinical discharge criteria are met. To test this, we measured visual evoked potentials (VEPs) in 13 ASA I or II patients who did not receive any pre-anaesthetic medication and underwent sevoflurane anaesthesia. VEPs were recorded on four occasions, before anaesthesia and at 30, 60, and 90 min after emergence from anaesthesia. Patients completed visual analogue scales (VAS) for sedation and anxiety, a Trieger Dot Test (TDT) and a Digit Symbol Substitution Test (DSST) immediately before each VEP recording. These results were compared using Student's t-test. P<0.05 was considered significant. VEP latency was prolonged (P<0.001) and amplitude diminished (P<0.05) at 30, 60, and 90 min after emergence from anaesthesia, when VAS scores for sedation and anxiety, TDT, and DSST had returned to pre-anaesthetic levels.en_GB
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshAnesthetics, Inhalation/*pharmacologyen_GB
dc.subject.meshCognition/*drug effectsen_GB
dc.subject.meshEvoked Potentials, Visual/*drug effectsen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMethyl Ethers/*pharmacologyen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPostoperative Perioden_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshPsychometricsen_GB
dc.subject.meshPsychomotor Performance/drug effectsen_GB
dc.subject.meshReaction Time/drug effectsen_GB
dc.titlePostoperative changes in visual evoked potentials and cognitive function tests following sevoflurane anaesthesia.en_GB
dc.contributor.departmentDepartment of Anaesthesia and Intensive Care Medicine, Cork University Hospital, and National University of Ireland, Republic of Ireland.en_GB
dc.identifier.journalBritish journal of anaesthesiaen_GB
dc.description.provinceMunster-

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