Health-related quality of life in patients with skull base tumours.

Hdl Handle:
http://hdl.handle.net/10147/209045
Title:
Health-related quality of life in patients with skull base tumours.
Authors:
Kelleher, M O; Fernandes, M F; Sim, D W; O'Sullivan, M G
Affiliation:
Department of Neurosurgery, Cork University Hospital, Cork, Eire, UK.
Citation:
Br J Neurosurg. 2002 Feb;16(1):16-20.
Journal:
British journal of neurosurgery
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/209045
PubMed ID:
11926460
Abstract:
The objective of the investigation was to report on the health-related quality of life (HRQoL) of patients diagnosed with skull base tumours using the Short Form Health Survey questionnaire (SF-36). Those patients suffering with vestibular schwannoma were examined to determine the effect facial nerve function had on their quality of life. It took place at the tertiary referral centre at the Department of Clinical Neurosciences, Western General Hospital, Edinburgh. A prospective study of 70 consecutive patients was taken, who harboured the following tumours: 54 vestibular schwannomas, 13 meningiomas, two haemangioblastomas and one hypoglossal schwannoma. Patients were interviewed using the short form 36 (SF-36) questionnaire. Facial nerve function was assessed in those patients who had vestibular schwannomas. The entire cohort of live skull base patients were assessed after a median follow-up time of 38.4 months. Patients with vestibular schwannoma treated conservatively with interval MRI had a quality of life similar to t he normal population. Those who underwent surgery had a significant difference in two of the SF-36 domains. No statistically significant correlation was found at final assessment between the degree of facial nerve functioning and any of the domains of SF-36. Patients with non-vestibular tumours had an impaired HRQoL in seven of the eight domains. Patients with skull base tumours have a significant impairment of their HRQoL. A conservative policy of follow up with interval MRI for patients with small vestibular schwannomas may therefore be more appropriate to preserve their HRQoL. Facial nerve outcome has little influence on quality of life in vestibular schwannoma patients.
Language:
eng
MeSH:
Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroma, Acoustic/pathology/rehabilitation/surgery; Prospective Studies; *Quality of Life; Questionnaires; Scotland; *Sickness Impact Profile; Skull Base Neoplasms/*rehabilitation/surgery; Treatment Outcome
ISSN:
0268-8697 (Print); 0268-8697 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorKelleher, M Oen_GB
dc.contributor.authorFernandes, M Fen_GB
dc.contributor.authorSim, D Wen_GB
dc.contributor.authorO'Sullivan, M Gen_GB
dc.date.accessioned2012-02-03T15:10:46Z-
dc.date.available2012-02-03T15:10:46Z-
dc.date.issued2012-02-03T15:10:46Z-
dc.identifier.citationBr J Neurosurg. 2002 Feb;16(1):16-20.en_GB
dc.identifier.issn0268-8697 (Print)en_GB
dc.identifier.issn0268-8697 (Linking)en_GB
dc.identifier.pmid11926460en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209045-
dc.description.abstractThe objective of the investigation was to report on the health-related quality of life (HRQoL) of patients diagnosed with skull base tumours using the Short Form Health Survey questionnaire (SF-36). Those patients suffering with vestibular schwannoma were examined to determine the effect facial nerve function had on their quality of life. It took place at the tertiary referral centre at the Department of Clinical Neurosciences, Western General Hospital, Edinburgh. A prospective study of 70 consecutive patients was taken, who harboured the following tumours: 54 vestibular schwannomas, 13 meningiomas, two haemangioblastomas and one hypoglossal schwannoma. Patients were interviewed using the short form 36 (SF-36) questionnaire. Facial nerve function was assessed in those patients who had vestibular schwannomas. The entire cohort of live skull base patients were assessed after a median follow-up time of 38.4 months. Patients with vestibular schwannoma treated conservatively with interval MRI had a quality of life similar to t he normal population. Those who underwent surgery had a significant difference in two of the SF-36 domains. No statistically significant correlation was found at final assessment between the degree of facial nerve functioning and any of the domains of SF-36. Patients with non-vestibular tumours had an impaired HRQoL in seven of the eight domains. Patients with skull base tumours have a significant impairment of their HRQoL. A conservative policy of follow up with interval MRI for patients with small vestibular schwannomas may therefore be more appropriate to preserve their HRQoL. Facial nerve outcome has little influence on quality of life in vestibular schwannoma patients.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFollow-Up Studiesen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshNeuroma, Acoustic/pathology/rehabilitation/surgeryen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.mesh*Quality of Lifeen_GB
dc.subject.meshQuestionnairesen_GB
dc.subject.meshScotlanden_GB
dc.subject.mesh*Sickness Impact Profileen_GB
dc.subject.meshSkull Base Neoplasms/*rehabilitation/surgeryen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.titleHealth-related quality of life in patients with skull base tumours.en_GB
dc.contributor.departmentDepartment of Neurosurgery, Cork University Hospital, Cork, Eire, UK.en_GB
dc.identifier.journalBritish journal of neurosurgeryen_GB
dc.description.provinceMunster-

Related articles on PubMed

All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.