Anticonvulsant use in elderly patients in long-term care units.

Hdl Handle:
http://hdl.handle.net/10147/208986
Title:
Anticonvulsant use in elderly patients in long-term care units.
Authors:
Timmons, S; McCarthy, F; Duggan, J; Twomey, C
Affiliation:
Department of Geriatric Medicine, Cork University Hospital, Cork, Ireland., suzannetimmons@hotmail.com
Citation:
Ir J Med Sci. 2003 Apr-Jun;172(2):66-8.
Journal:
Irish journal of medical science
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/208986
PubMed ID:
12930055
Abstract:
BACKGROUND: Elderly patients in long-term care units are frailer than their community-dwelling peers and may be more at risk from toxic side-effects of anticonvulsant medication at standard doses. AIM: To examine the prescribing of anticonvulsants to patients in elderly care units. METHODS: Drug prescription sheets and case notes were reviewed. Serum anticonvulsant concentration, renal and liver profiles and albumin level were measured. RESULTS: Anticonvulsants were prescribed to twice as many male as female patients (32 vs 14%; p<0.03) and to 33% of those younger than 80 years of age versus 10% of those aged 80 years or older (p<0.0002). No patient had significant hypoalbuminaemia and routine measurement of serum anticonvulsant concentration did not indicate an alteration of dosage. CONCLUSIONS: Anticonvulsants appear to be well tolerated in these patients. The younger age of those receiving anticonvulsants is inadequately explained by the characteristics of the patient cohort and may reflect a shift towards a younger age in patients requiring anticonvulsants due to increased mortality in this group.
Language:
eng
MeSH:
Aged; Aged, 80 and over; Anticonvulsants/*therapeutic use; Drug Interactions; Drug Utilization/statistics & numerical data; Female; *Health Services for the Aged; Humans; Long-Term Care; Male
ISSN:
0021-1265 (Print); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorTimmons, Sen_GB
dc.contributor.authorMcCarthy, Fen_GB
dc.contributor.authorDuggan, Jen_GB
dc.contributor.authorTwomey, Cen_GB
dc.date.accessioned2012-02-03T15:09:12Z-
dc.date.available2012-02-03T15:09:12Z-
dc.date.issued2012-02-03T15:09:12Z-
dc.identifier.citationIr J Med Sci. 2003 Apr-Jun;172(2):66-8.en_GB
dc.identifier.issn0021-1265 (Print)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid12930055en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208986-
dc.description.abstractBACKGROUND: Elderly patients in long-term care units are frailer than their community-dwelling peers and may be more at risk from toxic side-effects of anticonvulsant medication at standard doses. AIM: To examine the prescribing of anticonvulsants to patients in elderly care units. METHODS: Drug prescription sheets and case notes were reviewed. Serum anticonvulsant concentration, renal and liver profiles and albumin level were measured. RESULTS: Anticonvulsants were prescribed to twice as many male as female patients (32 vs 14%; p<0.03) and to 33% of those younger than 80 years of age versus 10% of those aged 80 years or older (p<0.0002). No patient had significant hypoalbuminaemia and routine measurement of serum anticonvulsant concentration did not indicate an alteration of dosage. CONCLUSIONS: Anticonvulsants appear to be well tolerated in these patients. The younger age of those receiving anticonvulsants is inadequately explained by the characteristics of the patient cohort and may reflect a shift towards a younger age in patients requiring anticonvulsants due to increased mortality in this group.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnticonvulsants/*therapeutic useen_GB
dc.subject.meshDrug Interactionsen_GB
dc.subject.meshDrug Utilization/statistics & numerical dataen_GB
dc.subject.meshFemaleen_GB
dc.subject.mesh*Health Services for the Ageden_GB
dc.subject.meshHumansen_GB
dc.subject.meshLong-Term Careen_GB
dc.subject.meshMaleen_GB
dc.titleAnticonvulsant use in elderly patients in long-term care units.en_GB
dc.contributor.departmentDepartment of Geriatric Medicine, Cork University Hospital, Cork, Ireland., suzannetimmons@hotmail.comen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceMunster-
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