The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.

Hdl Handle:
http://hdl.handle.net/10147/208970
Title:
The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.
Authors:
Manning, Brian J; O'Brien, Noel; Aravindan, Selvaraj; Cahill, Ronan A; McGreal, Gerald; Redmond, H Paul
Affiliation:
Department of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , bjmanning2002@yahoo.com
Citation:
Injury. 2004 Feb;35(2):121-4.
Journal:
Injury
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/208970
PubMed ID:
14736467
Abstract:
Although it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.
Language:
eng
MeSH:
Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal/*adverse effects; Aspirin/*adverse effects; *Blood Loss, Surgical; *Blood Transfusion; Case-Control Studies; Emergencies; Female; Femoral Neck Fractures/blood/*surgery; Fracture Fixation/methods; Hematocrit; Hemoglobins/analysis; Humans; Male; Preoperative Care/methods; Prospective Studies
ISSN:
0020-1383 (Print); 0020-1383 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorManning, Brian Jen_GB
dc.contributor.authorO'Brien, Noelen_GB
dc.contributor.authorAravindan, Selvarajen_GB
dc.contributor.authorCahill, Ronan Aen_GB
dc.contributor.authorMcGreal, Geralden_GB
dc.contributor.authorRedmond, H Paulen_GB
dc.date.accessioned2012-02-03T15:08:48Z-
dc.date.available2012-02-03T15:08:48Z-
dc.date.issued2012-02-03T15:08:48Z-
dc.identifier.citationInjury. 2004 Feb;35(2):121-4.en_GB
dc.identifier.issn0020-1383 (Print)en_GB
dc.identifier.issn0020-1383 (Linking)en_GB
dc.identifier.pmid14736467en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208970-
dc.description.abstractAlthough it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal/*adverse effectsen_GB
dc.subject.meshAspirin/*adverse effectsen_GB
dc.subject.mesh*Blood Loss, Surgicalen_GB
dc.subject.mesh*Blood Transfusionen_GB
dc.subject.meshCase-Control Studiesen_GB
dc.subject.meshEmergenciesen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFemoral Neck Fractures/blood/*surgeryen_GB
dc.subject.meshFracture Fixation/methodsen_GB
dc.subject.meshHematocriten_GB
dc.subject.meshHemoglobins/analysisen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPreoperative Care/methodsen_GB
dc.subject.meshProspective Studiesen_GB
dc.titleThe effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.en_GB
dc.contributor.departmentDepartment of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , bjmanning2002@yahoo.comen_GB
dc.identifier.journalInjuryen_GB
dc.description.provinceMunster-
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