Functional dyspepsia: the role of visceral hypersensitivity in its pathogenesis.

Hdl Handle:
http://hdl.handle.net/10147/208843
Title:
Functional dyspepsia: the role of visceral hypersensitivity in its pathogenesis.
Authors:
Keohane, John; Quigley, Eamonn M M
Affiliation:
Department of Medicine, Alimentary Pharmabiotic Centre, Clinical Sciences, Building, Cork University Hospital, Cork, Ireland.
Citation:
World J Gastroenterol. 2006 May 7;12(17):2672-6.
Journal:
World journal of gastroenterology : WJG
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/208843
PubMed ID:
16718751
Abstract:
Functional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD.
Language:
eng
MeSH:
Analgesics/pharmacology/therapeutic use; Central Nervous System/drug effects/physiopathology; Dyspepsia/drug therapy/*etiology/*physiopathology; Efferent Pathways/drug effects/physiopathology; Enteric Nervous System/drug effects/physiopathology; Food Hypersensitivity/complications/physiopathology; Gastrointestinal Tract/*innervation/*physiopathology; Helicobacter Infections/complications/physiopathology; Helicobacter pylori; Humans
ISSN:
1007-9327 (Print); 1007-9327 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorKeohane, Johnen_GB
dc.contributor.authorQuigley, Eamonn M Men_GB
dc.date.accessioned2012-02-03T15:05:10Z-
dc.date.available2012-02-03T15:05:10Z-
dc.date.issued2012-02-03T15:05:10Z-
dc.identifier.citationWorld J Gastroenterol. 2006 May 7;12(17):2672-6.en_GB
dc.identifier.issn1007-9327 (Print)en_GB
dc.identifier.issn1007-9327 (Linking)en_GB
dc.identifier.pmid16718751en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208843-
dc.description.abstractFunctional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD.en_GB
dc.language.isoengen_GB
dc.subject.meshAnalgesics/pharmacology/therapeutic useen_GB
dc.subject.meshCentral Nervous System/drug effects/physiopathologyen_GB
dc.subject.meshDyspepsia/drug therapy/*etiology/*physiopathologyen_GB
dc.subject.meshEfferent Pathways/drug effects/physiopathologyen_GB
dc.subject.meshEnteric Nervous System/drug effects/physiopathologyen_GB
dc.subject.meshFood Hypersensitivity/complications/physiopathologyen_GB
dc.subject.meshGastrointestinal Tract/*innervation/*physiopathologyen_GB
dc.subject.meshHelicobacter Infections/complications/physiopathologyen_GB
dc.subject.meshHelicobacter pylorien_GB
dc.subject.meshHumansen_GB
dc.titleFunctional dyspepsia: the role of visceral hypersensitivity in its pathogenesis.en_GB
dc.contributor.departmentDepartment of Medicine, Alimentary Pharmabiotic Centre, Clinical Sciences, Building, Cork University Hospital, Cork, Ireland.en_GB
dc.identifier.journalWorld journal of gastroenterology : WJGen_GB
dc.description.provinceMunster-

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