Cellular reprogramming by gram-positive bacterial components: a review.

Hdl Handle:
http://hdl.handle.net/10147/208828
Title:
Cellular reprogramming by gram-positive bacterial components: a review.
Authors:
Buckley, Julliette M; Wang, Jiang Huai; Redmond, H Paul
Affiliation:
Department of Academic Surgery, Cork University Hospital, National University of , Ireland/University College Cork, Wilton, Cork, Ireland.
Citation:
J Leukoc Biol. 2006 Oct;80(4):731-41. Epub 2006 Aug 2.
Journal:
Journal of leukocyte biology
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/208828
DOI:
10.1189/jlb.0506312
PubMed ID:
16885502
Abstract:
LPS tolerance has been the focus of extensive scientific and clinical research over the last several decades in an attempt to elucidate the sequence of changes that occur at a molecular level in tolerized cells. Tolerance to components of gram-positive bacterial cell walls such as bacterial lipoprotein and lipoteichoic acid is a much lesser studied, although equally important, phenomenon. This review will focus on cellular reprogramming by gram-positive bacterial components and examines the alterations in cell surface receptor expression, changes in intracellular signaling, gene expression and cytokine production, and the phenomenon of cross-tolerance.
Language:
eng
MeSH:
Animals; Cytokines/biosynthesis/drug effects; Gram-Positive Bacteria/*immunology; Humans; Immune Tolerance/immunology; Lipopolysaccharides/immunology/*pharmacology; Lipoproteins/*pharmacology; Receptors, Cell Surface/biosynthesis/*drug effects/immunology; Signal Transduction/*drug effects/immunology; Teichoic Acids/*pharmacology
ISSN:
0741-5400 (Print); 0741-5400 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorBuckley, Julliette Men_GB
dc.contributor.authorWang, Jiang Huaien_GB
dc.contributor.authorRedmond, H Paulen_GB
dc.date.accessioned2012-02-03T15:04:42Z-
dc.date.available2012-02-03T15:04:42Z-
dc.date.issued2012-02-03T15:04:42Z-
dc.identifier.citationJ Leukoc Biol. 2006 Oct;80(4):731-41. Epub 2006 Aug 2.en_GB
dc.identifier.issn0741-5400 (Print)en_GB
dc.identifier.issn0741-5400 (Linking)en_GB
dc.identifier.pmid16885502en_GB
dc.identifier.doi10.1189/jlb.0506312en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208828-
dc.description.abstractLPS tolerance has been the focus of extensive scientific and clinical research over the last several decades in an attempt to elucidate the sequence of changes that occur at a molecular level in tolerized cells. Tolerance to components of gram-positive bacterial cell walls such as bacterial lipoprotein and lipoteichoic acid is a much lesser studied, although equally important, phenomenon. This review will focus on cellular reprogramming by gram-positive bacterial components and examines the alterations in cell surface receptor expression, changes in intracellular signaling, gene expression and cytokine production, and the phenomenon of cross-tolerance.en_GB
dc.language.isoengen_GB
dc.subject.meshAnimalsen_GB
dc.subject.meshCytokines/biosynthesis/drug effectsen_GB
dc.subject.meshGram-Positive Bacteria/*immunologyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshImmune Tolerance/immunologyen_GB
dc.subject.meshLipopolysaccharides/immunology/*pharmacologyen_GB
dc.subject.meshLipoproteins/*pharmacologyen_GB
dc.subject.meshReceptors, Cell Surface/biosynthesis/*drug effects/immunologyen_GB
dc.subject.meshSignal Transduction/*drug effects/immunologyen_GB
dc.subject.meshTeichoic Acids/*pharmacologyen_GB
dc.titleCellular reprogramming by gram-positive bacterial components: a review.en_GB
dc.contributor.departmentDepartment of Academic Surgery, Cork University Hospital, National University of , Ireland/University College Cork, Wilton, Cork, Ireland.en_GB
dc.identifier.journalJournal of leukocyte biologyen_GB
dc.description.provinceMunster-

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