Management of chronic constipation in the elderly.

Hdl Handle:
http://hdl.handle.net/10147/208818
Title:
Management of chronic constipation in the elderly.
Authors:
Gallagher, Paul F; O'Mahony, Denis; Quigley, Eamonn M M
Affiliation:
Department of Geriatric Medicine, Cork University Hospital, Alimentary, Pharmabiotic Centre, University College Cork, Cork, Ireland.
Citation:
Drugs Aging. 2008;25(10):807-21.
Journal:
Drugs & aging
Issue Date:
3-Feb-2012
URI:
http://hdl.handle.net/10147/208818
PubMed ID:
18808206
Abstract:
Constipation is a significant healthcare problem in the elderly. However, while undoubtedly common in the elderly, data on the prevalence of constipation in general and of its subtypes vary considerably, depending on the nature of the study population and their location. Furthermore, the complexity of the pathophysiology of constipation in this age group is little appreciated. Assumptions regarding 'age-related changes in colorectal physiology' are, for the most part, not supported by scientific evidence and may serve to distract the clinician from uncovering the contributions of co-morbid diseases and the impact of iatrogenic factors. The evidence base from which one can develop recommendations on the management of constipation in the elderly is, for the most part, slim. This becomes most starkly apparent when one attempts to critically assess specific approaches to management. There is insufficient evidence to support the use of many commonly used laxatives both in the general population and in the elderly. Lifestyle interventions have value for some patients but data are lacking on the benefits of these interventions for patients with chronic constipation. Data in the elderly do not exist for most new pharmacological approaches to constipation. Pending the availability of good data, management of constipation in the elderly should be tailored to each individual's needs and expectations, regardless of age or place of residence. In certain situations, constipation may be complicated by the development of impaction; preventive strategies are important in this context. We urge enrolment of many more elderly individuals with chronic constipation in clinical trials designed to address their particular needs.
Language:
eng
MeSH:
Aged; Chronic Disease; Constipation/complications/physiopathology/*therapy; Fecal Impaction/complications/therapy; *Health Services for the Aged; Humans; Laxatives/therapeutic use; Life Style; Suppositories/therapeutic use
ISSN:
1170-229X (Print); 1170-229X (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorGallagher, Paul Fen_GB
dc.contributor.authorO'Mahony, Denisen_GB
dc.contributor.authorQuigley, Eamonn M Men_GB
dc.date.accessioned2012-02-03T15:04:20Z-
dc.date.available2012-02-03T15:04:20Z-
dc.date.issued2012-02-03T15:04:20Z-
dc.identifier.citationDrugs Aging. 2008;25(10):807-21.en_GB
dc.identifier.issn1170-229X (Print)en_GB
dc.identifier.issn1170-229X (Linking)en_GB
dc.identifier.pmid18808206en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208818-
dc.description.abstractConstipation is a significant healthcare problem in the elderly. However, while undoubtedly common in the elderly, data on the prevalence of constipation in general and of its subtypes vary considerably, depending on the nature of the study population and their location. Furthermore, the complexity of the pathophysiology of constipation in this age group is little appreciated. Assumptions regarding 'age-related changes in colorectal physiology' are, for the most part, not supported by scientific evidence and may serve to distract the clinician from uncovering the contributions of co-morbid diseases and the impact of iatrogenic factors. The evidence base from which one can develop recommendations on the management of constipation in the elderly is, for the most part, slim. This becomes most starkly apparent when one attempts to critically assess specific approaches to management. There is insufficient evidence to support the use of many commonly used laxatives both in the general population and in the elderly. Lifestyle interventions have value for some patients but data are lacking on the benefits of these interventions for patients with chronic constipation. Data in the elderly do not exist for most new pharmacological approaches to constipation. Pending the availability of good data, management of constipation in the elderly should be tailored to each individual's needs and expectations, regardless of age or place of residence. In certain situations, constipation may be complicated by the development of impaction; preventive strategies are important in this context. We urge enrolment of many more elderly individuals with chronic constipation in clinical trials designed to address their particular needs.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshChronic Diseaseen_GB
dc.subject.meshConstipation/complications/physiopathology/*therapyen_GB
dc.subject.meshFecal Impaction/complications/therapyen_GB
dc.subject.mesh*Health Services for the Ageden_GB
dc.subject.meshHumansen_GB
dc.subject.meshLaxatives/therapeutic useen_GB
dc.subject.meshLife Styleen_GB
dc.subject.meshSuppositories/therapeutic useen_GB
dc.titleManagement of chronic constipation in the elderly.en_GB
dc.contributor.departmentDepartment of Geriatric Medicine, Cork University Hospital, Alimentary, Pharmabiotic Centre, University College Cork, Cork, Ireland.en_GB
dc.identifier.journalDrugs & agingen_GB
dc.description.provinceMunster-

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