Human papillomavirus vaccination in the prevention of cervical neoplasia.

Hdl Handle:
http://hdl.handle.net/10147/208035
Title:
Human papillomavirus vaccination in the prevention of cervical neoplasia.
Authors:
Astbury, Katharine; Turner, Michael J
Affiliation:
Department of Obstetrics and Gynaecology, Coombe Women's Hospital, Dublin,, Ireland. kathastbury@gmail.com
Citation:
Int J Gynecol Cancer. 2009 Dec;19(9):1610-3.
Journal:
International journal of gynecological cancer : official journal of the, International Gynecological Cancer Society
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/208035
DOI:
10.1111/IGC.0b013e3181a8411b
PubMed ID:
19955947
Abstract:
Cervical cancer remains a major cause of morbidity and mortality for women worldwide. Although the introduction of comprehensive screening programs has reduced the disease incidence in developed countries, it remains a major problem in the developing world. The recent licensing of 2 vaccines against human papillomavirus (HPV) type 16 and HPV-18, the viruses responsible for 70% of cervical cancer cases, offers the hope of disease prevention. In this article, we review the role of HPV in the etiology of cervical cancer and the evidence to support the introduction of vaccination programs in young women and discuss the potential obstacles to widespread vaccination. In addition, we discuss the issues that remain to be elucidated, including the potential need for booster doses of the vaccine and the role of concomitant vaccination in men.
Language:
eng
MeSH:
Cervical Intraepithelial Neoplasia/etiology/immunology/*prevention & control; Female; Humans; Immunity, Active/physiology; Male; Papillomavirus Infections/complications/immunology/*prevention & control; Papillomavirus Vaccines/biosynthesis/immunology/*therapeutic use; Treatment Outcome; Uterine Cervical Neoplasms/etiology/immunology/*prevention & control; *Vaccination/economics/methods
ISSN:
1525-1438 (Electronic); 1048-891X (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorAstbury, Katharineen_GB
dc.contributor.authorTurner, Michael Jen_GB
dc.date.accessioned2012-02-01T10:58:21Z-
dc.date.available2012-02-01T10:58:21Z-
dc.date.issued2012-02-01T10:58:21Z-
dc.identifier.citationInt J Gynecol Cancer. 2009 Dec;19(9):1610-3.en_GB
dc.identifier.issn1525-1438 (Electronic)en_GB
dc.identifier.issn1048-891X (Linking)en_GB
dc.identifier.pmid19955947en_GB
dc.identifier.doi10.1111/IGC.0b013e3181a8411ben_GB
dc.identifier.urihttp://hdl.handle.net/10147/208035-
dc.description.abstractCervical cancer remains a major cause of morbidity and mortality for women worldwide. Although the introduction of comprehensive screening programs has reduced the disease incidence in developed countries, it remains a major problem in the developing world. The recent licensing of 2 vaccines against human papillomavirus (HPV) type 16 and HPV-18, the viruses responsible for 70% of cervical cancer cases, offers the hope of disease prevention. In this article, we review the role of HPV in the etiology of cervical cancer and the evidence to support the introduction of vaccination programs in young women and discuss the potential obstacles to widespread vaccination. In addition, we discuss the issues that remain to be elucidated, including the potential need for booster doses of the vaccine and the role of concomitant vaccination in men.en_GB
dc.language.isoengen_GB
dc.subject.meshCervical Intraepithelial Neoplasia/etiology/immunology/*prevention & controlen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshImmunity, Active/physiologyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPapillomavirus Infections/complications/immunology/*prevention & controlen_GB
dc.subject.meshPapillomavirus Vaccines/biosynthesis/immunology/*therapeutic useen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshUterine Cervical Neoplasms/etiology/immunology/*prevention & controlen_GB
dc.subject.mesh*Vaccination/economics/methodsen_GB
dc.titleHuman papillomavirus vaccination in the prevention of cervical neoplasia.en_GB
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, Coombe Women's Hospital, Dublin,, Ireland. kathastbury@gmail.comen_GB
dc.identifier.journalInternational journal of gynecological cancer : official journal of the, International Gynecological Cancer Societyen_GB
dc.description.provinceLeinster-

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