Changes in intraocular pressure and anterior segment morphometry after uneventful phacoemulsification cataract surgery.

Hdl Handle:
http://hdl.handle.net/10147/207967
Title:
Changes in intraocular pressure and anterior segment morphometry after uneventful phacoemulsification cataract surgery.
Authors:
Dooley, I; Charalampidou, S; Malik, A; Loughman, J; Molloy, L; Beatty, S
Affiliation:
Department of Ophthalmology, Waterford Regional Hospital, Waterford, Ireland., iandooley@eustace.net
Citation:
Eye (Lond). 2010 Apr;24(4):519-26; quiz 527. Epub 2010 Feb 19.
Journal:
Eye (London, England)
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207967
DOI:
10.1038/eye.2009.339
PubMed ID:
20168346
Abstract:
PURPOSE: To study changes in anterior segment morphometry after uneventful phacoemulsification cataract surgery, and to investigate whether there is a relationship between any observed changes and intraocular pressure (IOP) reduction after the procedure. METHODS: The anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness (CCT), and IOP were measured in 101 non-glaucomatous eyes before and after uneventful phacoemulsification cataract surgery. RESULTS: After cataract surgery, the mean ACD, ACV, and ACA values increased by 1.08 mm, 54.4 mm(3), and 13.1 degrees , respectively, and the mean IOP (corrected for CCT) decreased by 3.2 mm Hg. The predictive value of a previously described index (preoperative ACD/preoperative IOP (corrected for CCT) or CPD ratio) for IOP (corrected for CCT) reduction after cataract surgery was confirmed, reflected in an r(2) value of 23.3% between these two parameters (P<0.001). Other indices predictive of IOP reduction after cataract surgery were also identified, including preoperative IOP/preoperative ACV and preoperative IOP/preoperative ACA, reflected in r(2) values of 13.7 and 13.7%, respectively (P<0.001 and P<0.001, respectively). CONCLUSIONS: Our study confirms the predictive value of the CPD ratio for IOP reduction after cataract surgery, and may contribute to the decision-making process in patients with glaucoma or ocular hypertension. Furthermore, two novel indices of preoperative parameters that are predictive for IOP reduction after cataract surgery were identified, and enhance our understanding of the mechanisms underlying IOP changes after this procedure.
Language:
eng
MeSH:
Aged; Aged, 80 and over; Anterior Chamber/*pathology; Cornea/pathology; Female; Humans; Intraocular Pressure/*physiology; Male; Middle Aged; *Phacoemulsification; Prospective Studies
ISSN:
1476-5454 (Electronic); 0950-222X (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorDooley, Ien_GB
dc.contributor.authorCharalampidou, Sen_GB
dc.contributor.authorMalik, Aen_GB
dc.contributor.authorLoughman, Jen_GB
dc.contributor.authorMolloy, Len_GB
dc.contributor.authorBeatty, Sen_GB
dc.date.accessioned2012-02-01T10:52:49Z-
dc.date.available2012-02-01T10:52:49Z-
dc.date.issued2012-02-01T10:52:49Z-
dc.identifier.citationEye (Lond). 2010 Apr;24(4):519-26; quiz 527. Epub 2010 Feb 19.en_GB
dc.identifier.issn1476-5454 (Electronic)en_GB
dc.identifier.issn0950-222X (Linking)en_GB
dc.identifier.pmid20168346en_GB
dc.identifier.doi10.1038/eye.2009.339en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207967-
dc.description.abstractPURPOSE: To study changes in anterior segment morphometry after uneventful phacoemulsification cataract surgery, and to investigate whether there is a relationship between any observed changes and intraocular pressure (IOP) reduction after the procedure. METHODS: The anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness (CCT), and IOP were measured in 101 non-glaucomatous eyes before and after uneventful phacoemulsification cataract surgery. RESULTS: After cataract surgery, the mean ACD, ACV, and ACA values increased by 1.08 mm, 54.4 mm(3), and 13.1 degrees , respectively, and the mean IOP (corrected for CCT) decreased by 3.2 mm Hg. The predictive value of a previously described index (preoperative ACD/preoperative IOP (corrected for CCT) or CPD ratio) for IOP (corrected for CCT) reduction after cataract surgery was confirmed, reflected in an r(2) value of 23.3% between these two parameters (P<0.001). Other indices predictive of IOP reduction after cataract surgery were also identified, including preoperative IOP/preoperative ACV and preoperative IOP/preoperative ACA, reflected in r(2) values of 13.7 and 13.7%, respectively (P<0.001 and P<0.001, respectively). CONCLUSIONS: Our study confirms the predictive value of the CPD ratio for IOP reduction after cataract surgery, and may contribute to the decision-making process in patients with glaucoma or ocular hypertension. Furthermore, two novel indices of preoperative parameters that are predictive for IOP reduction after cataract surgery were identified, and enhance our understanding of the mechanisms underlying IOP changes after this procedure.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnterior Chamber/*pathologyen_GB
dc.subject.meshCornea/pathologyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIntraocular Pressure/*physiologyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.mesh*Phacoemulsificationen_GB
dc.subject.meshProspective Studiesen_GB
dc.titleChanges in intraocular pressure and anterior segment morphometry after uneventful phacoemulsification cataract surgery.en_GB
dc.contributor.departmentDepartment of Ophthalmology, Waterford Regional Hospital, Waterford, Ireland., iandooley@eustace.neten_GB
dc.identifier.journalEye (London, England)en_GB
dc.description.provinceMunster-
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