Hdl Handle:
http://hdl.handle.net/10147/207934
Title:
Neuroendocrine tumors of the pancreas.
Authors:
Davies, Karen; Conlon, Kevin C
Affiliation:
Department of Surgery, Trinity College Dublin, The Adelaide and Meath Hospital, incorporating the National Children's Hospital, Tallaght, Dublin 24, Ireland.
Citation:
Curr Gastroenterol Rep. 2009 Apr;11(2):119-27.
Journal:
Current gastroenterology reports
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207934
PubMed ID:
19281699
Abstract:
Pancreatic endocrine tumors are rare neoplasms accounting for less than 5% of pancreatic malignancies. They are broadly classified into either functioning tumors (insulinomas, gastrinomas, glucagonomas, VIPomas, and somatostatinomas) or nonfunctioning tumors. The diagnosis of these tumors is difficult and requires a careful history and examination combined with laboratory tests and radiologic imaging. Signs and symptoms are usually related to hormone hypersecretion in the case of functioning tumors and to tumor size or metastases with nonfunctioning tumors. Surgical resection remains the treatment of choice even in the face of metastatic disease. Further development of novel diagnostic and treatment modalities offers potential to greatly improve quality of life and prolong disease-free survival for patients with pancreatic endocrine tumors.
Language:
eng
MeSH:
*Adenoma, Islet Cell/pathology/secretion/therapy; Algorithms; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; *Carcinoma, Islet Cell/pathology/secretion/therapy; Catheter Ablation; Chemoembolization, Therapeutic/methods; Evidence-Based Medicine; Gastrins/secretion; Glucagon/secretion; Humans; Insulin/secretion; *Pancreatic Neoplasms/pathology/secretion/therapy; Quality of Life; Somatostatin/secretion; Survival Analysis; Treatment Outcome
ISSN:
1534-312X (Electronic); 1522-8037 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorDavies, Karenen_GB
dc.contributor.authorConlon, Kevin Cen_GB
dc.date.accessioned2012-02-01T10:50:32Z-
dc.date.available2012-02-01T10:50:32Z-
dc.date.issued2012-02-01T10:50:32Z-
dc.identifier.citationCurr Gastroenterol Rep. 2009 Apr;11(2):119-27.en_GB
dc.identifier.issn1534-312X (Electronic)en_GB
dc.identifier.issn1522-8037 (Linking)en_GB
dc.identifier.pmid19281699en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207934-
dc.description.abstractPancreatic endocrine tumors are rare neoplasms accounting for less than 5% of pancreatic malignancies. They are broadly classified into either functioning tumors (insulinomas, gastrinomas, glucagonomas, VIPomas, and somatostatinomas) or nonfunctioning tumors. The diagnosis of these tumors is difficult and requires a careful history and examination combined with laboratory tests and radiologic imaging. Signs and symptoms are usually related to hormone hypersecretion in the case of functioning tumors and to tumor size or metastases with nonfunctioning tumors. Surgical resection remains the treatment of choice even in the face of metastatic disease. Further development of novel diagnostic and treatment modalities offers potential to greatly improve quality of life and prolong disease-free survival for patients with pancreatic endocrine tumors.en_GB
dc.language.isoengen_GB
dc.subject.mesh*Adenoma, Islet Cell/pathology/secretion/therapyen_GB
dc.subject.meshAlgorithmsen_GB
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols/therapeutic useen_GB
dc.subject.mesh*Carcinoma, Islet Cell/pathology/secretion/therapyen_GB
dc.subject.meshCatheter Ablationen_GB
dc.subject.meshChemoembolization, Therapeutic/methodsen_GB
dc.subject.meshEvidence-Based Medicineen_GB
dc.subject.meshGastrins/secretionen_GB
dc.subject.meshGlucagon/secretionen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInsulin/secretionen_GB
dc.subject.mesh*Pancreatic Neoplasms/pathology/secretion/therapyen_GB
dc.subject.meshQuality of Lifeen_GB
dc.subject.meshSomatostatin/secretionen_GB
dc.subject.meshSurvival Analysisen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.titleNeuroendocrine tumors of the pancreas.en_GB
dc.contributor.departmentDepartment of Surgery, Trinity College Dublin, The Adelaide and Meath Hospital, incorporating the National Children's Hospital, Tallaght, Dublin 24, Ireland.en_GB
dc.identifier.journalCurrent gastroenterology reportsen_GB
dc.description.provinceLeinster-

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