Primary angiitis of the central nervous system with diffuse cerebral mass effect and giant cells.

Hdl Handle:
http://hdl.handle.net/10147/207905
Title:
Primary angiitis of the central nervous system with diffuse cerebral mass effect and giant cells.
Authors:
Kinsella, J A; O'Brien, W; Mullins, G M; Brewer, J; Whyte, S
Affiliation:
Department of Neurology, The Adelaide and Meath Hospital, Dublin, Incorporating, the National Children's Hospital, Trinity College Dublin, Tallaght, Dublin 24,, Ireland. justinkinsella@gmail.com <justinkinsella@gmail.com>
Citation:
J Clin Neurosci. 2010 May;17(5):674-6. Epub 2010 Mar 19.
Journal:
Journal of clinical neuroscience : official journal of the Neurosurgical Society , of Australasia
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207905
DOI:
10.1016/j.jocn.2009.09.031
PubMed ID:
20303761
Abstract:
Primary angiitis of the central nervous system (PACNS), also called primary CNS vasculitis, is an idiopathic inflammatory condition affecting only intracranial and spinal cord vessels, particularly medium-sized and smaller arteries and arterioles. Angiography and histopathology typically do not reveal evidence of systemic vasculitis.(1,2) Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma and/or leptomeninges, similar to that seen in Takayasu's or giant cell arteritis.(1-3) We report a patient with biopsy-proven PACNS with giant cells and cerebral mass effect on MRI. Magnetic resonance angiography and cerebral angiography appeared normal and there was no evidence of extracranial vasculitis.
Language:
eng
MeSH:
Aged, 80 and over; Anti-Inflammatory Agents/therapeutic use; Brain/*pathology/radiography; Cerebral Angiography; Cerebrovascular Circulation; Female; Giant Cells/*pathology; Humans; Magnetic Resonance Imaging; Prednisolone/therapeutic use; Treatment Outcome; Vasculitis, Central Nervous System/drug therapy/*pathology/radiography
ISSN:
1532-2653 (Electronic); 0967-5868 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorKinsella, J Aen_GB
dc.contributor.authorO'Brien, Wen_GB
dc.contributor.authorMullins, G Men_GB
dc.contributor.authorBrewer, Jen_GB
dc.contributor.authorWhyte, Sen_GB
dc.date.accessioned2012-02-01T10:49:41Z-
dc.date.available2012-02-01T10:49:41Z-
dc.date.issued2012-02-01T10:49:41Z-
dc.identifier.citationJ Clin Neurosci. 2010 May;17(5):674-6. Epub 2010 Mar 19.en_GB
dc.identifier.issn1532-2653 (Electronic)en_GB
dc.identifier.issn0967-5868 (Linking)en_GB
dc.identifier.pmid20303761en_GB
dc.identifier.doi10.1016/j.jocn.2009.09.031en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207905-
dc.description.abstractPrimary angiitis of the central nervous system (PACNS), also called primary CNS vasculitis, is an idiopathic inflammatory condition affecting only intracranial and spinal cord vessels, particularly medium-sized and smaller arteries and arterioles. Angiography and histopathology typically do not reveal evidence of systemic vasculitis.(1,2) Histopathology usually reveals granulomatous inflammation affecting arterioles and small arteries of the parenchyma and/or leptomeninges, similar to that seen in Takayasu's or giant cell arteritis.(1-3) We report a patient with biopsy-proven PACNS with giant cells and cerebral mass effect on MRI. Magnetic resonance angiography and cerebral angiography appeared normal and there was no evidence of extracranial vasculitis.en_GB
dc.language.isoengen_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnti-Inflammatory Agents/therapeutic useen_GB
dc.subject.meshBrain/*pathology/radiographyen_GB
dc.subject.meshCerebral Angiographyen_GB
dc.subject.meshCerebrovascular Circulationen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshGiant Cells/*pathologyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMagnetic Resonance Imagingen_GB
dc.subject.meshPrednisolone/therapeutic useen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshVasculitis, Central Nervous System/drug therapy/*pathology/radiographyen_GB
dc.titlePrimary angiitis of the central nervous system with diffuse cerebral mass effect and giant cells.en_GB
dc.contributor.departmentDepartment of Neurology, The Adelaide and Meath Hospital, Dublin, Incorporating, the National Children's Hospital, Trinity College Dublin, Tallaght, Dublin 24,, Ireland. justinkinsella@gmail.com <justinkinsella@gmail.com>en_GB
dc.identifier.journalJournal of clinical neuroscience : official journal of the Neurosurgical Society , of Australasiaen_GB
dc.description.provinceLeinster-

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