Efficacy of triamcinolone acetonide and bupivacaine for pain after lumbar discectomy.

Hdl Handle:
http://hdl.handle.net/10147/207903
Title:
Efficacy of triamcinolone acetonide and bupivacaine for pain after lumbar discectomy.
Authors:
Bahari, Syah; El-Dahab, Mohamed; Cleary, May; Sparkes, Joseph
Affiliation:
Department of Trauma and Reconstructive Surgery, Adelaide and Meath Hospital, incorporating the National Children Hospital, Tallaght, Dublin 24, Republic of, Ireland. syahbahari@gmail.com
Citation:
Eur Spine J. 2010 Jul;19(7):1099-103. Epub 2010 Mar 12.
Journal:
European spine journal : official publication of the European Spine Society, the , European Spinal Deformity Society, and the European Section of the Cervical Spine, Research Society
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207903
DOI:
10.1007/s00586-010-1360-7
PubMed ID:
20224868
Abstract:
The study is a prospective blinded randomised controlled trial to compare the efficacy of triamcinolone acetonide, bupivacaine or in combination in managing pain after lumbar discectomy. Patients undergoing primary single-level lumbar discectomy were randomised. Triamcinolone acetonide, bupivacaine or in combination was instilled at the nerve root as decompression. Preoperative, day 1 and 6 weeks pain score, 24-h postoperative opiate requirements and duration of inpatient stay were recorded. Data was analysed using Mann-Whitney test for statistical significance. 100 patients were recruited. A significant difference was noted in day one postoperative mean pain score, mean 24-h opiate requirement and mean inpatient stay in the triamcinolone acetonide and bupivacaine group. At 8 weeks postoperatively, no significant differences were seen in the pain score in all groups. Significant postoperative pain reduction and opiate requirements in the first 24 h, and significantly shortened duration of inpatient stay were achieved in the triamcinolone acetonide and bupivacaine group compared with other groups.
Language:
eng
MeSH:
Analgesia/methods; Anesthetics, Local/therapeutic use; Anti-Inflammatory Agents/therapeutic use; Bupivacaine/*therapeutic use; *Diskectomy; Drug Therapy, Combination; Female; Humans; Lumbar Vertebrae/*surgery; Male; Pain Measurement/*drug effects; Pain, Postoperative/*drug therapy; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; Triamcinolone Acetonide/*therapeutic use
ISSN:
1432-0932 (Electronic); 0940-6719 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorBahari, Syahen_GB
dc.contributor.authorEl-Dahab, Mohameden_GB
dc.contributor.authorCleary, Mayen_GB
dc.contributor.authorSparkes, Josephen_GB
dc.date.accessioned2012-02-01T10:49:37Z-
dc.date.available2012-02-01T10:49:37Z-
dc.date.issued2012-02-01T10:49:37Z-
dc.identifier.citationEur Spine J. 2010 Jul;19(7):1099-103. Epub 2010 Mar 12.en_GB
dc.identifier.issn1432-0932 (Electronic)en_GB
dc.identifier.issn0940-6719 (Linking)en_GB
dc.identifier.pmid20224868en_GB
dc.identifier.doi10.1007/s00586-010-1360-7en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207903-
dc.description.abstractThe study is a prospective blinded randomised controlled trial to compare the efficacy of triamcinolone acetonide, bupivacaine or in combination in managing pain after lumbar discectomy. Patients undergoing primary single-level lumbar discectomy were randomised. Triamcinolone acetonide, bupivacaine or in combination was instilled at the nerve root as decompression. Preoperative, day 1 and 6 weeks pain score, 24-h postoperative opiate requirements and duration of inpatient stay were recorded. Data was analysed using Mann-Whitney test for statistical significance. 100 patients were recruited. A significant difference was noted in day one postoperative mean pain score, mean 24-h opiate requirement and mean inpatient stay in the triamcinolone acetonide and bupivacaine group. At 8 weeks postoperatively, no significant differences were seen in the pain score in all groups. Significant postoperative pain reduction and opiate requirements in the first 24 h, and significantly shortened duration of inpatient stay were achieved in the triamcinolone acetonide and bupivacaine group compared with other groups.en_GB
dc.language.isoengen_GB
dc.subject.meshAnalgesia/methodsen_GB
dc.subject.meshAnesthetics, Local/therapeutic useen_GB
dc.subject.meshAnti-Inflammatory Agents/therapeutic useen_GB
dc.subject.meshBupivacaine/*therapeutic useen_GB
dc.subject.mesh*Diskectomyen_GB
dc.subject.meshDrug Therapy, Combinationen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLumbar Vertebrae/*surgeryen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPain Measurement/*drug effectsen_GB
dc.subject.meshPain, Postoperative/*drug therapyen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshStatistics, Nonparametricen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshTriamcinolone Acetonide/*therapeutic useen_GB
dc.titleEfficacy of triamcinolone acetonide and bupivacaine for pain after lumbar discectomy.en_GB
dc.contributor.departmentDepartment of Trauma and Reconstructive Surgery, Adelaide and Meath Hospital, incorporating the National Children Hospital, Tallaght, Dublin 24, Republic of, Ireland. syahbahari@gmail.comen_GB
dc.identifier.journalEuropean spine journal : official publication of the European Spine Society, the , European Spinal Deformity Society, and the European Section of the Cervical Spine, Research Societyen_GB
dc.description.provinceLeinster-
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