Non-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?

Hdl Handle:
http://hdl.handle.net/10147/207889
Title:
Non-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?
Authors:
Kitchen, J; Kane, D
Affiliation:
Department of Rheumatology, Adelaide and Meath Hospital incorporating the, National Children's Hospital, Tallaght, Dublin 24, Ireland. kitchen.jo@gmail.com
Citation:
Ir J Med Sci. 2010 Sep;179(3):357-60. Epub 2010 May 30.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207889
DOI:
10.1007/s11845-010-0496-0
PubMed ID:
20512664
Abstract:
AIM: To determine non-steroidal anti-inflammatory drug (NSAID) prescribing practices in a tertiary referral hospital. METHODS: A single time-point audit of drug kardexes and clinical notes of n = 388 patients on 2 July 2008 was carried out assessing demographics, gastrointestinal and coronary heart disease risk factors, renal function and co-prescribed medications. RESULTS: Fifty-seven of 388 (14.7%) hospital patients were on NSAIDs. Forty-nine were prescribed NSAID after admission. Nineteen (32.2%) were on regular NSAID (11/19 on PPI) and 38 patients were on PRN NSAID (12/38 on PPI). Seventeen of 49 patients were on other medications associated with gastrointestinal bleeding (10/17 were on PPI). Nineteen patients (33.3%) were >60 years. Eight patients had three or four risk factors for gastrointestinal bleeding; six were on PPI. Thirteen patients had two risks; 7 were on PPI. Six of 19 patients with one risk factor were on PPI. 40.3% had stage 2/3 chronic kidney disease. 35.1% had ischaemic heart disease. CONCLUSIONS: NSAIDs and PPIs are often prescribed inappropriately.
Language:
eng
MeSH:
Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use; Gastrointestinal Hemorrhage/epidemiology; Hospitalization; Humans; Inappropriate Prescribing/*statistics & numerical data; Ireland; Medical Audit; Physician's Practice Patterns/*statistics & numerical data; Proton Pump Inhibitors/therapeutic use; Renal Insufficiency, Chronic/epidemiology; Risk Factors
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorKitchen, Jen_GB
dc.contributor.authorKane, Den_GB
dc.date.accessioned2012-02-01T10:49:13Z-
dc.date.available2012-02-01T10:49:13Z-
dc.date.issued2012-02-01T10:49:13Z-
dc.identifier.citationIr J Med Sci. 2010 Sep;179(3):357-60. Epub 2010 May 30.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid20512664en_GB
dc.identifier.doi10.1007/s11845-010-0496-0en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207889-
dc.description.abstractAIM: To determine non-steroidal anti-inflammatory drug (NSAID) prescribing practices in a tertiary referral hospital. METHODS: A single time-point audit of drug kardexes and clinical notes of n = 388 patients on 2 July 2008 was carried out assessing demographics, gastrointestinal and coronary heart disease risk factors, renal function and co-prescribed medications. RESULTS: Fifty-seven of 388 (14.7%) hospital patients were on NSAIDs. Forty-nine were prescribed NSAID after admission. Nineteen (32.2%) were on regular NSAID (11/19 on PPI) and 38 patients were on PRN NSAID (12/38 on PPI). Seventeen of 49 patients were on other medications associated with gastrointestinal bleeding (10/17 were on PPI). Nineteen patients (33.3%) were >60 years. Eight patients had three or four risk factors for gastrointestinal bleeding; six were on PPI. Thirteen patients had two risks; 7 were on PPI. Six of 19 patients with one risk factor were on PPI. 40.3% had stage 2/3 chronic kidney disease. 35.1% had ischaemic heart disease. CONCLUSIONS: NSAIDs and PPIs are often prescribed inappropriately.en_GB
dc.language.isoengen_GB
dc.subject.meshAnti-Inflammatory Agents, Non-Steroidal/*therapeutic useen_GB
dc.subject.meshGastrointestinal Hemorrhage/epidemiologyen_GB
dc.subject.meshHospitalizationen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInappropriate Prescribing/*statistics & numerical dataen_GB
dc.subject.meshIrelanden_GB
dc.subject.meshMedical Auditen_GB
dc.subject.meshPhysician's Practice Patterns/*statistics & numerical dataen_GB
dc.subject.meshProton Pump Inhibitors/therapeutic useen_GB
dc.subject.meshRenal Insufficiency, Chronic/epidemiologyen_GB
dc.subject.meshRisk Factorsen_GB
dc.titleNon-steroidal anti-inflammatory drug prescriptions in hospital inpatients: are we assessing the risks?en_GB
dc.contributor.departmentDepartment of Rheumatology, Adelaide and Meath Hospital incorporating the, National Children's Hospital, Tallaght, Dublin 24, Ireland. kitchen.jo@gmail.comen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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