Complete clinical response to neoadjuvant chemotherapy in a 54-year-old male with Askin tumor.
Affiliation
Department of Surgery, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland., jmulsow@rcsi.ieIssue Date
2012-02-01T10:48:04ZMeSH
Antineoplastic Combined Chemotherapy Protocols/*therapeutic useBiopsy
Chemotherapy, Adjuvant
Humans
Male
Middle Aged
Neoadjuvant Therapy
Neuroectodermal Tumors, Primitive/*drug therapy/pathology/surgery
Thoracic Neoplasms/*drug therapy/pathology/surgery
Tomography, X-Ray Computed
Treatment Outcome
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Thorac Cardiovasc Surg. 2010 Aug;58(5):306-8. Epub 2010 Aug 2.Journal
The Thoracic and cardiovascular surgeonDOI
10.1055/s-0029-1186198PubMed ID
20680911Abstract
Askin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents. These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis. Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above. Surgery is advocated in most cases. We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy. This allowed potentially radical surgery to be avoided. At one-year follow-up he remains disease-free.Language
engISSN
1439-1902 (Electronic)0171-6425 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1055/s-0029-1186198
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