A changing trend in the management of patients with newly diagnosed Crohn's disease.

Hdl Handle:
http://hdl.handle.net/10147/207851
Title:
A changing trend in the management of patients with newly diagnosed Crohn's disease.
Authors:
Qasim, A; Ullah, N; Crotty, P; Swan, N; Breslin, N; Ryan, B; Torreggiani, W; Eguare, E; Neary, P; O'Connor, H; O'Morain, C
Affiliation:
Adelaide and Meath Hospital, Tallaght/Trinity College, Dublin, Ireland., asgharqasim@yahoo.co.uk
Citation:
Ir J Med Sci. 2011 Sep;180(3):643-7. Epub 2011 Mar 23.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207851
DOI:
10.1007/s11845-011-0706-4
PubMed ID:
21431393
Abstract:
BACKGROUND: Epidemiologic shift with rising incidence of Crohn's disease (CD) has been reported in recent studies. AIMS: To determine disease behaviour and therapeutic interventions undertaken in newly diagnosed patients with CD. METHODS: Patients diagnosed with CD between January 2006 and June 2008 were included. Disease type, location, degree of involvement and type of therapeutic interventions were recorded. RESULTS: A total of 78 patients were included. Colonic, ileo-colonic, terminal ileal and isolated small bowel disease were present in 37, 27, 9 and 5 patients, respectively. Disease phenotype was inflammatory, stenosing and fistulising in 42, 30 and 6 patients, respectively. Surgery was required in 22 patients, including right hemicolectomy (n = 8), subtotal colectomy (n = 4), segmental colonic resection (n = 2), segmental small bowel resection (n = 2), appendectomy (n = 2) and perianal surgery (n = 4). Fourteen patients underwent surgery at the time of diagnosis. Laparoscopic surgery was performed in 14 patients. CONCLUSIONS: A significant proportion of newly diagnosed patients with CD underwent surgical intervention on their first admission to hospital. This may signify a changing trend in the management approach.
Language:
eng
MeSH:
Adolescent; Adult; Aged; Colectomy/*statistics & numerical data; Crohn Disease/epidemiology/mortality/pathology/*surgery; Female; Humans; Incidence; Male; Middle Aged; Young Adult
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorQasim, Aen_GB
dc.contributor.authorUllah, Nen_GB
dc.contributor.authorCrotty, Pen_GB
dc.contributor.authorSwan, Nen_GB
dc.contributor.authorBreslin, Nen_GB
dc.contributor.authorRyan, Ben_GB
dc.contributor.authorTorreggiani, Wen_GB
dc.contributor.authorEguare, Een_GB
dc.contributor.authorNeary, Pen_GB
dc.contributor.authorO'Connor, Hen_GB
dc.contributor.authorO'Morain, Cen_GB
dc.date.accessioned2012-02-01T10:48:03Z-
dc.date.available2012-02-01T10:48:03Z-
dc.date.issued2012-02-01T10:48:03Z-
dc.identifier.citationIr J Med Sci. 2011 Sep;180(3):643-7. Epub 2011 Mar 23.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid21431393en_GB
dc.identifier.doi10.1007/s11845-011-0706-4en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207851-
dc.description.abstractBACKGROUND: Epidemiologic shift with rising incidence of Crohn's disease (CD) has been reported in recent studies. AIMS: To determine disease behaviour and therapeutic interventions undertaken in newly diagnosed patients with CD. METHODS: Patients diagnosed with CD between January 2006 and June 2008 were included. Disease type, location, degree of involvement and type of therapeutic interventions were recorded. RESULTS: A total of 78 patients were included. Colonic, ileo-colonic, terminal ileal and isolated small bowel disease were present in 37, 27, 9 and 5 patients, respectively. Disease phenotype was inflammatory, stenosing and fistulising in 42, 30 and 6 patients, respectively. Surgery was required in 22 patients, including right hemicolectomy (n = 8), subtotal colectomy (n = 4), segmental colonic resection (n = 2), segmental small bowel resection (n = 2), appendectomy (n = 2) and perianal surgery (n = 4). Fourteen patients underwent surgery at the time of diagnosis. Laparoscopic surgery was performed in 14 patients. CONCLUSIONS: A significant proportion of newly diagnosed patients with CD underwent surgical intervention on their first admission to hospital. This may signify a changing trend in the management approach.en_GB
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshColectomy/*statistics & numerical dataen_GB
dc.subject.meshCrohn Disease/epidemiology/mortality/pathology/*surgeryen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIncidenceen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshYoung Adulten_GB
dc.titleA changing trend in the management of patients with newly diagnosed Crohn's disease.en_GB
dc.contributor.departmentAdelaide and Meath Hospital, Tallaght/Trinity College, Dublin, Ireland., asgharqasim@yahoo.co.uken_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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