Prospective, blinded trial of whole-body magnetic resonance imaging versus computed tomography positron emission tomography in staging primary and recurrent cancer of the head and neck.
Affiliation
Department of Otolaryngology, Head and Neck Surgery, The Mater Hospital, Dublin, , Ireland. joneill@rcsi.ieIssue Date
2012-02-01T11:08:56ZMeSH
AdultAged
Aged, 80 and over
Biopsy
Female
Fluorodeoxyglucose F18/diagnostic use
Head and Neck Neoplasms/*diagnosis/pathology/radionuclide imaging
Humans
Magnetic Resonance Imaging/*methods
Male
Middle Aged
Neoplasm Recurrence, Local/diagnosis/radionuclide imaging
Neoplasm Staging
*Positron-Emission Tomography
Predictive Value of Tests
Prospective Studies
Radiopharmaceuticals/diagnostic use
Whole Body Imaging/*methods
Young Adult
Metadata
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J Laryngol Otol. 2010 Dec;124(12):1274-7. Epub 2010 Jun 11.Journal
The Journal of laryngology and otologyDOI
10.1017/S0022215110001398PubMed ID
20537210Abstract
OBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation.Language
engISSN
1748-5460 (Electronic)0022-2151 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1017/S0022215110001398
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