Risk and outcome analysis of 1832 consecutively excised basal cell carcinomas in a tertiary referral plastic surgery unit.

Hdl Handle:
http://hdl.handle.net/10147/207833
Title:
Risk and outcome analysis of 1832 consecutively excised basal cell carcinomas in a tertiary referral plastic surgery unit.
Authors:
Malik, Vinod; Goh, King Soon; Leong, Sum; Tan, Angeline; Downey, David; O'Donovan, David
Affiliation:
Department of Plastic Surgery, St James Hospital, James's Street, Dublin 8,, Ireland. malikv54@hotmail.com
Citation:
J Plast Reconstr Aesthet Surg. 2010 Dec;63(12):2057-63. Epub 2010 Mar 11.
Journal:
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207833
DOI:
10.1016/j.bjps.2010.01.016
PubMed ID:
20226750
Abstract:
BACKGROUND: Basal cell carcinomas are the most prevalent of all skin cancers worldwide and form the majority of the surgical workload for most modern cutaneous malignancy centres. Primary surgical removal of basal cell carcinomas remains the gold standard of treatment but, despite almost two centuries of surgical experience, rates of incomplete surgical excision of up to 50% are still reported. The aim of this study was to assess, quantify and perform comparative analysis of the outcomes and predictive factors of consecutive primarily-excised basal cell carcinomas in a tertiary centre over a six-year period. METHODS: Retrospective audit was conducted on all patients who underwent surgical excision of basal cell carcinomas from January 2000 to December 2005. Assessment parameters included patient biographics, tumour management differences and detailed histopathological analysis of tumour margins and subtypes. RESULTS: One thousand eight hundred and thirty two basal cell carcinomas were excised from 1329 patients over the designated time period. Two hundred and fifty one (14%) lesions were incompletely excised with 135 (7.4%) involving the peripheral margin only, 48 (2.6%) the deep margin only and 41 (2.2%) involving both. Nasal location was the most common predictor of incomplete excision. CONCLUSIONS: Overall basal cell carcinomas excision rates compared favourably with international reported standards but attention to a variety of surgical and histological risk factors may improve this further.
Language:
eng
MeSH:
Adult; Aged; Aged, 80 and over; Carcinoma, Basal Cell/*surgery; Cheek; Female; Head and Neck Neoplasms/*surgery; Humans; Male; Middle Aged; Nose Neoplasms/surgery; Retrospective Studies; Skin Neoplasms/*surgery; Treatment Outcome; Young Adult
ISSN:
1878-0539 (Electronic); 1748-6815 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorMalik, Vinoden_GB
dc.contributor.authorGoh, King Soonen_GB
dc.contributor.authorLeong, Sumen_GB
dc.contributor.authorTan, Angelineen_GB
dc.contributor.authorDowney, Daviden_GB
dc.contributor.authorO'Donovan, Daviden_GB
dc.date.accessioned2012-02-01T10:46:00Z-
dc.date.available2012-02-01T10:46:00Z-
dc.date.issued2012-02-01T10:46:00Z-
dc.identifier.citationJ Plast Reconstr Aesthet Surg. 2010 Dec;63(12):2057-63. Epub 2010 Mar 11.en_GB
dc.identifier.issn1878-0539 (Electronic)en_GB
dc.identifier.issn1748-6815 (Linking)en_GB
dc.identifier.pmid20226750en_GB
dc.identifier.doi10.1016/j.bjps.2010.01.016en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207833-
dc.description.abstractBACKGROUND: Basal cell carcinomas are the most prevalent of all skin cancers worldwide and form the majority of the surgical workload for most modern cutaneous malignancy centres. Primary surgical removal of basal cell carcinomas remains the gold standard of treatment but, despite almost two centuries of surgical experience, rates of incomplete surgical excision of up to 50% are still reported. The aim of this study was to assess, quantify and perform comparative analysis of the outcomes and predictive factors of consecutive primarily-excised basal cell carcinomas in a tertiary centre over a six-year period. METHODS: Retrospective audit was conducted on all patients who underwent surgical excision of basal cell carcinomas from January 2000 to December 2005. Assessment parameters included patient biographics, tumour management differences and detailed histopathological analysis of tumour margins and subtypes. RESULTS: One thousand eight hundred and thirty two basal cell carcinomas were excised from 1329 patients over the designated time period. Two hundred and fifty one (14%) lesions were incompletely excised with 135 (7.4%) involving the peripheral margin only, 48 (2.6%) the deep margin only and 41 (2.2%) involving both. Nasal location was the most common predictor of incomplete excision. CONCLUSIONS: Overall basal cell carcinomas excision rates compared favourably with international reported standards but attention to a variety of surgical and histological risk factors may improve this further.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshCarcinoma, Basal Cell/*surgeryen_GB
dc.subject.meshCheeken_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHead and Neck Neoplasms/*surgeryen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshNose Neoplasms/surgeryen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshSkin Neoplasms/*surgeryen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshYoung Adulten_GB
dc.titleRisk and outcome analysis of 1832 consecutively excised basal cell carcinomas in a tertiary referral plastic surgery unit.en_GB
dc.contributor.departmentDepartment of Plastic Surgery, St James Hospital, James's Street, Dublin 8,, Ireland. malikv54@hotmail.comen_GB
dc.identifier.journalJournal of plastic, reconstructive & aesthetic surgery : JPRASen_GB
dc.description.provinceLeinster-
All Items in Lenus, The Irish Health Repository are protected by copyright, with all rights reserved, unless otherwise indicated.