Ligands, cell-based models, and readouts required for Toll-like receptor action.

Hdl Handle:
http://hdl.handle.net/10147/207788
Title:
Ligands, cell-based models, and readouts required for Toll-like receptor action.
Authors:
Dellacasagrande, Jerome
Affiliation:
OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James', Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.com
Citation:
Methods Mol Biol. 2009;517:15-32.
Journal:
Methods in molecular biology (Clifton, N.J.)
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207788
DOI:
10.1007/978-1-59745-541-1_2
PubMed ID:
19378025
Abstract:
This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.
Language:
eng
MeSH:
Animals; Cell Line; Gene Expression Regulation/*genetics; Genes, Reporter/genetics; Humans; Ligands; *Models, Biological; Phosphorylation; Protein Transport; Toll-Like Receptors/*analysis/classification/genetics/*metabolism; Transcription, Genetic/genetics
ISSN:
1064-3745 (Print); 1064-3745 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorDellacasagrande, Jeromeen_GB
dc.date.accessioned2012-02-01T10:44:44Z-
dc.date.available2012-02-01T10:44:44Z-
dc.date.issued2012-02-01T10:44:44Z-
dc.identifier.citationMethods Mol Biol. 2009;517:15-32.en_GB
dc.identifier.issn1064-3745 (Print)en_GB
dc.identifier.issn1064-3745 (Linking)en_GB
dc.identifier.pmid19378025en_GB
dc.identifier.doi10.1007/978-1-59745-541-1_2en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207788-
dc.description.abstractThis chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.en_GB
dc.language.isoengen_GB
dc.subject.meshAnimalsen_GB
dc.subject.meshCell Lineen_GB
dc.subject.meshGene Expression Regulation/*geneticsen_GB
dc.subject.meshGenes, Reporter/geneticsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLigandsen_GB
dc.subject.mesh*Models, Biologicalen_GB
dc.subject.meshPhosphorylationen_GB
dc.subject.meshProtein Transporten_GB
dc.subject.meshToll-Like Receptors/*analysis/classification/genetics/*metabolismen_GB
dc.subject.meshTranscription, Genetic/geneticsen_GB
dc.titleLigands, cell-based models, and readouts required for Toll-like receptor action.en_GB
dc.contributor.departmentOPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James', Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.comen_GB
dc.identifier.journalMethods in molecular biology (Clifton, N.J.)en_GB
dc.description.provinceLeinster-

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