A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers.
Authors
Shuhaibar, MWalsh, C
Lindsay, F
Lee, N
Walsh, P
O'Gorman, P
Boran, G
McLoughlin, R
Qasim, A
Breslin, N
Ryan, B
O'Connor, H
O'Morain, C
Affiliation
Department of Gastroenterology/Clinical Medicine, Trinity College Dublin, Trinity, Centre for Health Sciences, The Adelaide and Meath Hospital, Tallaght, Dublin,, Ireland. shuhaibm@tcd.ieIssue Date
2012-02-01T10:47:45ZMeSH
Cohort StudiesColectomy
Colorectal Neoplasms/*diagnosis/epidemiology/surgery
Guaiac/diagnostic use
Humans
Indicators and Reagents
Male
Mass Screening/methods
Middle Aged
*Occult Blood
*Occupational Health
Metadata
Show full item recordCitation
Ir J Med Sci. 2011 Mar;180(1):103-8. Epub 2010 Oct 17.Journal
Irish journal of medical scienceDOI
10.1007/s11845-010-0605-0PubMed ID
20953981Abstract
BACKGROUND: The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening. METHODS: A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy. RESULTS: A total of 909 faecal testing kits were distributed. Age range was 53-60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polyps and CRC in 37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016). CONCLUSION: The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.Language
engISSN
1863-4362 (Electronic)0021-1265 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1007/s11845-010-0605-0
Scopus Count
Collections
Related articles
- Faecal immunochemical tests versus guaiac faecal occult blood tests: what clinicians and colorectal cancer screening programme organisers need to know.
- Authors: Tinmouth J, Lansdorp-Vogelaar I, Allison JE
- Issue date: 2015 Aug
- Switching from guaiac to immunochemical faecal occult blood test increases participation and diagnostic yield of colorectal cancer screening.
- Authors: Bretagne JF, Piette C, Cosson M, Durand G, Lièvre A
- Issue date: 2019 Oct
- Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy.
- Authors: Hol L, van Leerdam ME, van Ballegooijen M, van Vuuren AJ, van Dekken H, Reijerink JC, van der Togt AC, Habbema JD, Kuipers EJ
- Issue date: 2010 Jan
- Cost-effectiveness of the faecal immunochemical test at a range of positivity thresholds compared with the guaiac faecal occult blood test in the NHS Bowel Cancer Screening Programme in England.
- Authors: Murphy J, Halloran S, Gray A
- Issue date: 2017 Oct 27
- Supply and quality of colonoscopy according to the characteristics of gastroenterologists in the French population-based colorectal-cancer screening program.
- Authors: Koïvogui A, Vincelet C, Abihsera G, Ait-Hadad H, Delattre H, Le Trung T, Bernoux A, Carroll R, Nicolet J
- Issue date: 2023 Mar 7