A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers.

Hdl Handle:
http://hdl.handle.net/10147/207763
Title:
A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers.
Authors:
Shuhaibar, M; Walsh, C; Lindsay, F; Lee, N; Walsh, P; O'Gorman, P; Boran, G; McLoughlin, R; Qasim, A; Breslin, N; Ryan, B; O'Connor, H; O'Morain, C
Affiliation:
Department of Gastroenterology/Clinical Medicine, Trinity College Dublin, Trinity, Centre for Health Sciences, The Adelaide and Meath Hospital, Tallaght, Dublin,, Ireland. shuhaibm@tcd.ie
Citation:
Ir J Med Sci. 2011 Mar;180(1):103-8. Epub 2010 Oct 17.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207763
DOI:
10.1007/s11845-010-0605-0
PubMed ID:
20953981
Abstract:
BACKGROUND: The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening. METHODS: A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy. RESULTS: A total of 909 faecal testing kits were distributed. Age range was 53-60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polyps and CRC in 37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016). CONCLUSION: The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.
Language:
eng
MeSH:
Cohort Studies; Colectomy; Colorectal Neoplasms/*diagnosis/epidemiology/surgery; Guaiac/diagnostic use; Humans; Indicators and Reagents; Male; Mass Screening/methods; Middle Aged; *Occult Blood; *Occupational Health
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorShuhaibar, Men_GB
dc.contributor.authorWalsh, Cen_GB
dc.contributor.authorLindsay, Fen_GB
dc.contributor.authorLee, Nen_GB
dc.contributor.authorWalsh, Pen_GB
dc.contributor.authorO'Gorman, Pen_GB
dc.contributor.authorBoran, Gen_GB
dc.contributor.authorMcLoughlin, Ren_GB
dc.contributor.authorQasim, Aen_GB
dc.contributor.authorBreslin, Nen_GB
dc.contributor.authorRyan, Ben_GB
dc.contributor.authorO'Connor, Hen_GB
dc.contributor.authorO'Morain, Cen_GB
dc.date.accessioned2012-02-01T10:47:45Z-
dc.date.available2012-02-01T10:47:45Z-
dc.date.issued2012-02-01T10:47:45Z-
dc.identifier.citationIr J Med Sci. 2011 Mar;180(1):103-8. Epub 2010 Oct 17.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid20953981en_GB
dc.identifier.doi10.1007/s11845-010-0605-0en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207763-
dc.description.abstractBACKGROUND: The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening. METHODS: A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy. RESULTS: A total of 909 faecal testing kits were distributed. Age range was 53-60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polyps and CRC in 37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016). CONCLUSION: The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.en_GB
dc.language.isoengen_GB
dc.subject.meshCohort Studiesen_GB
dc.subject.meshColectomyen_GB
dc.subject.meshColorectal Neoplasms/*diagnosis/epidemiology/surgeryen_GB
dc.subject.meshGuaiac/diagnostic useen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIndicators and Reagentsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMass Screening/methodsen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.mesh*Occult Blooden_GB
dc.subject.mesh*Occupational Healthen_GB
dc.titleA comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers.en_GB
dc.contributor.departmentDepartment of Gastroenterology/Clinical Medicine, Trinity College Dublin, Trinity, Centre for Health Sciences, The Adelaide and Meath Hospital, Tallaght, Dublin,, Ireland. shuhaibm@tcd.ieen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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