Clinical observations associated with proven and unproven cases in the ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery.

Hdl Handle:
http://hdl.handle.net/10147/207752
Title:
Clinical observations associated with proven and unproven cases in the ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery.
Authors:
Barry, Peter; Gardner, Susanne; Seal, David; Gettinby, George; Lees, Fiona; Peterson, Magnus; Revie, Crawford
Affiliation:
Royal Victoria Eye and Ear Hospital, Dublin, Ireland. peterbarryfrcs@eircom.net
Citation:
J Cataract Refract Surg. 2009 Sep;35(9):1523-31, 1531.e1.
Journal:
Journal of cataract and refractive surgery
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207752
DOI:
10.1016/j.jcrs.2009.03.049
PubMed ID:
19683148
Abstract:
PURPOSE: To describe cases of postoperative endophthalmitis in the European Society of Cataract & Refractive Surgeons (ESCRS) study of the prophylaxis of endophthalmitis, compare characteristics of unproven cases and cases proven by culture or polymerase chain reaction, and compare the characteristics with those in other reported series. SETTING: Twenty-four ophthalmology units in Austria, Belgium, Germany, Italy, Poland, Portugal, Spain, Turkey, and the United Kingdom. METHODS: Univariable and multivariable logistic regression models were used to analyze data for statistical association of signs and symptoms in cases with proven or unproven endophthalmitis. Specific data describing characteristics of the cases were compared between the 2 types of cases. RESULTS: Data from 29 endophthalmitis cases were analyzed. Swollen lids and pain were statistically associated with proven cases of endophthalmitis on univariable regression analysis. Multivariable analysis indicated that swollen lids and an opaque vitreous were associated with proven cases. Five cases of endophthalmitis occurred in the cefuroxime-treated groups. No case of streptococcal infection occurred in the cefuroxime-treated groups. However, cases of infection due to streptococci showed striking differences in visual acuity and were associated with earlier onset. Characteristics in the 29 cases parallel results in previous studies, such as the Endophthalmitis Vitrectomy Study, although the addition of a control group in the ESCRS study elicited additional findings. CONCLUSION: Swollen lids, pain, and an opaque vitreous were statistically associated with proven endophthalmitis cases in the ESCRS study.
Language:
eng
MeSH:
Aged; Aged, 80 and over; Anti-Bacterial Agents/therapeutic use; Cefuroxime/therapeutic use; Endophthalmitis/*diagnosis/drug therapy/microbiology; Eye Diseases/*diagnosis; Eye Infections, Bacterial/*diagnosis/drug therapy/microbiology; Eyelid Diseases/*diagnosis; Female; Humans; Lens Implantation, Intraocular; Male; Middle Aged; Pain/*diagnosis; Phacoemulsification; Polymerase Chain Reaction; *Postoperative Complications; Time Factors; Visual Acuity; Vitreous Body/*pathology
ISSN:
1873-4502 (Electronic); 0886-3350 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorBarry, Peteren_GB
dc.contributor.authorGardner, Susanneen_GB
dc.contributor.authorSeal, Daviden_GB
dc.contributor.authorGettinby, Georgeen_GB
dc.contributor.authorLees, Fionaen_GB
dc.contributor.authorPeterson, Magnusen_GB
dc.contributor.authorRevie, Crawforden_GB
dc.date.accessioned2012-02-01T10:40:10Z-
dc.date.available2012-02-01T10:40:10Z-
dc.date.issued2012-02-01T10:40:10Z-
dc.identifier.citationJ Cataract Refract Surg. 2009 Sep;35(9):1523-31, 1531.e1.en_GB
dc.identifier.issn1873-4502 (Electronic)en_GB
dc.identifier.issn0886-3350 (Linking)en_GB
dc.identifier.pmid19683148en_GB
dc.identifier.doi10.1016/j.jcrs.2009.03.049en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207752-
dc.description.abstractPURPOSE: To describe cases of postoperative endophthalmitis in the European Society of Cataract & Refractive Surgeons (ESCRS) study of the prophylaxis of endophthalmitis, compare characteristics of unproven cases and cases proven by culture or polymerase chain reaction, and compare the characteristics with those in other reported series. SETTING: Twenty-four ophthalmology units in Austria, Belgium, Germany, Italy, Poland, Portugal, Spain, Turkey, and the United Kingdom. METHODS: Univariable and multivariable logistic regression models were used to analyze data for statistical association of signs and symptoms in cases with proven or unproven endophthalmitis. Specific data describing characteristics of the cases were compared between the 2 types of cases. RESULTS: Data from 29 endophthalmitis cases were analyzed. Swollen lids and pain were statistically associated with proven cases of endophthalmitis on univariable regression analysis. Multivariable analysis indicated that swollen lids and an opaque vitreous were associated with proven cases. Five cases of endophthalmitis occurred in the cefuroxime-treated groups. No case of streptococcal infection occurred in the cefuroxime-treated groups. However, cases of infection due to streptococci showed striking differences in visual acuity and were associated with earlier onset. Characteristics in the 29 cases parallel results in previous studies, such as the Endophthalmitis Vitrectomy Study, although the addition of a control group in the ESCRS study elicited additional findings. CONCLUSION: Swollen lids, pain, and an opaque vitreous were statistically associated with proven endophthalmitis cases in the ESCRS study.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshAnti-Bacterial Agents/therapeutic useen_GB
dc.subject.meshCefuroxime/therapeutic useen_GB
dc.subject.meshEndophthalmitis/*diagnosis/drug therapy/microbiologyen_GB
dc.subject.meshEye Diseases/*diagnosisen_GB
dc.subject.meshEye Infections, Bacterial/*diagnosis/drug therapy/microbiologyen_GB
dc.subject.meshEyelid Diseases/*diagnosisen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLens Implantation, Intraocularen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPain/*diagnosisen_GB
dc.subject.meshPhacoemulsificationen_GB
dc.subject.meshPolymerase Chain Reactionen_GB
dc.subject.mesh*Postoperative Complicationsen_GB
dc.subject.meshTime Factorsen_GB
dc.subject.meshVisual Acuityen_GB
dc.subject.meshVitreous Body/*pathologyen_GB
dc.titleClinical observations associated with proven and unproven cases in the ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery.en_GB
dc.contributor.departmentRoyal Victoria Eye and Ear Hospital, Dublin, Ireland. peterbarryfrcs@eircom.neten_GB
dc.identifier.journalJournal of cataract and refractive surgeryen_GB
dc.description.provinceLeinster-

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