First Irish birth following IVF therapy using antagonist protocol.

Hdl Handle:
http://hdl.handle.net/10147/207717
Title:
First Irish birth following IVF therapy using antagonist protocol.
Authors:
Mocanu, E V; Kondaveeti, N; Kelly, J; Hennelly, B; Burke, L; Hughes, C
Affiliation:
HARI Unit, Rotunda Hospital, Dublin 1, Ireland. emocanu@rcsi.ie
Citation:
Ir J Med Sci. 2010 Sep;179(3):455-7. Epub 2009 Apr 4.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207717
DOI:
10.1007/s11845-009-0336-2
PubMed ID:
19347389
Abstract:
BACKGROUND: During in vitro fertilization (IVF), the prevention of a premature LH surge was traditionally achieved using a gonadotrophin releasing hormone agonist (GnRH-a), and more recently, a GnRH antagonist. AIMS: We report a case of a 37 year old treated using the GnRH antagonist in a second completed cycle of IVF. METHODS: IVF was performed for primary infertility of 5-year duration due to frozen pelvis secondary to endometriosis. RESULTS: Following controlled ovarian hyperstimulation, oocyte recovery and fertilization, cleavage and transfer of two zygotes, a pregnancy established. A twin gestation was diagnosed at 7-weeks scan and pregnancy ended with the delivery of twin girls by emergency caesarean section. CONCLUSION: This is a first report of a delivery following IVF using the antagonist protocol in Ireland. Such therapy is patient friendly and its use should be introduced on a larger scale in clinical practice.
Language:
eng
MeSH:
Adult; Cesarean Section; Female; Fertilization in Vitro/*methods; Follicle Stimulating Hormone, Human/administration & dosage; Gonadotropin-Releasing Hormone/administration & dosage/*analogs &; derivatives/*antagonists & inhibitors; Humans; Ireland; Live Birth; Pregnancy; Pregnancy Outcome; Pregnancy, Multiple; Twins; Zygote Intrafallopian Transfer
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorMocanu, E Ven_GB
dc.contributor.authorKondaveeti, Nen_GB
dc.contributor.authorKelly, Jen_GB
dc.contributor.authorHennelly, Ben_GB
dc.contributor.authorBurke, Len_GB
dc.contributor.authorHughes, Cen_GB
dc.date.accessioned2012-02-01T10:37:53Z-
dc.date.available2012-02-01T10:37:53Z-
dc.date.issued2012-02-01T10:37:53Z-
dc.identifier.citationIr J Med Sci. 2010 Sep;179(3):455-7. Epub 2009 Apr 4.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid19347389en_GB
dc.identifier.doi10.1007/s11845-009-0336-2en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207717-
dc.description.abstractBACKGROUND: During in vitro fertilization (IVF), the prevention of a premature LH surge was traditionally achieved using a gonadotrophin releasing hormone agonist (GnRH-a), and more recently, a GnRH antagonist. AIMS: We report a case of a 37 year old treated using the GnRH antagonist in a second completed cycle of IVF. METHODS: IVF was performed for primary infertility of 5-year duration due to frozen pelvis secondary to endometriosis. RESULTS: Following controlled ovarian hyperstimulation, oocyte recovery and fertilization, cleavage and transfer of two zygotes, a pregnancy established. A twin gestation was diagnosed at 7-weeks scan and pregnancy ended with the delivery of twin girls by emergency caesarean section. CONCLUSION: This is a first report of a delivery following IVF using the antagonist protocol in Ireland. Such therapy is patient friendly and its use should be introduced on a larger scale in clinical practice.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshCesarean Sectionen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFertilization in Vitro/*methodsen_GB
dc.subject.meshFollicle Stimulating Hormone, Human/administration & dosageen_GB
dc.subject.meshGonadotropin-Releasing Hormone/administration & dosage/*analogs &en_GB
dc.subject.meshderivatives/*antagonists & inhibitorsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIrelanden_GB
dc.subject.meshLive Birthen_GB
dc.subject.meshPregnancyen_GB
dc.subject.meshPregnancy Outcomeen_GB
dc.subject.meshPregnancy, Multipleen_GB
dc.subject.meshTwinsen_GB
dc.subject.meshZygote Intrafallopian Transferen_GB
dc.titleFirst Irish birth following IVF therapy using antagonist protocol.en_GB
dc.contributor.departmentHARI Unit, Rotunda Hospital, Dublin 1, Ireland. emocanu@rcsi.ieen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-
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