Hdl Handle:
http://hdl.handle.net/10147/207646
Title:
Pap smears for men: a vision of the future?
Authors:
Oon, S F; Hanly, A; Winter, D C
Affiliation:
Department of Colorectal Surgery, St. Vincent's University Hospital, Elm Park,, Dublin 4, Ireland. sheng-fei.oon@ucd.ie
Citation:
Ir J Med Sci. 2010 Sep;179(3):459-62. Epub 2009 Sep 11.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207646
DOI:
10.1007/s11845-009-0340-6
PubMed ID:
19763675
Abstract:
BACKGROUND: Anal intraepithelial neoplasia (AIN) rarely receives as much publicity as its neighbouring orifice, the cervix. As in the cervix, intraepithelial neoplasias are precursors to cancer in the anal canal. AIN and cervical interstitial neoplasia (CIN) undergo dysplasia as a consequence of human papillomavirus (HPV) infection. Since the advent of screening with the Pap smear in CIN, cervical cancer has plummeted to a fifth of its initial incidence. Anal cancer, however, has been rising, with a predilection for human immunodeficiency virus-infected men. HPV causes a squamous epithelial dysplasia and converts healthy tissue into AINs of increasing severity until anal cancer manifests. CLINICAL CASE: This article describes a clinical case of anogenital HPV infection refractory to medical and surgical therapy. It also describes an effective surgical excision technique associated with a good cosmetic outcome. CONCLUSIONS: The paper concludes by briefly discussing the implications of a national screening programme against AIN in the future.
Language:
eng
MeSH:
Adult; Anus Diseases/surgery/therapy/virology; Anus Neoplasms/diagnosis/*virology; Carcinoma in Situ/diagnosis/*virology; Cervical Intraepithelial Neoplasia/virology; Condylomata Acuminata/surgery/therapy/virology; Cytodiagnosis; Female; Humans; Male; Papillomavirus Infections; Recurrence; Uterine Cervical Neoplasms/virology
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorOon, S Fen_GB
dc.contributor.authorHanly, Aen_GB
dc.contributor.authorWinter, D Cen_GB
dc.date.accessioned2012-02-01T10:33:50Z-
dc.date.available2012-02-01T10:33:50Z-
dc.date.issued2012-02-01T10:33:50Z-
dc.identifier.citationIr J Med Sci. 2010 Sep;179(3):459-62. Epub 2009 Sep 11.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid19763675en_GB
dc.identifier.doi10.1007/s11845-009-0340-6en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207646-
dc.description.abstractBACKGROUND: Anal intraepithelial neoplasia (AIN) rarely receives as much publicity as its neighbouring orifice, the cervix. As in the cervix, intraepithelial neoplasias are precursors to cancer in the anal canal. AIN and cervical interstitial neoplasia (CIN) undergo dysplasia as a consequence of human papillomavirus (HPV) infection. Since the advent of screening with the Pap smear in CIN, cervical cancer has plummeted to a fifth of its initial incidence. Anal cancer, however, has been rising, with a predilection for human immunodeficiency virus-infected men. HPV causes a squamous epithelial dysplasia and converts healthy tissue into AINs of increasing severity until anal cancer manifests. CLINICAL CASE: This article describes a clinical case of anogenital HPV infection refractory to medical and surgical therapy. It also describes an effective surgical excision technique associated with a good cosmetic outcome. CONCLUSIONS: The paper concludes by briefly discussing the implications of a national screening programme against AIN in the future.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAnus Diseases/surgery/therapy/virologyen_GB
dc.subject.meshAnus Neoplasms/diagnosis/*virologyen_GB
dc.subject.meshCarcinoma in Situ/diagnosis/*virologyen_GB
dc.subject.meshCervical Intraepithelial Neoplasia/virologyen_GB
dc.subject.meshCondylomata Acuminata/surgery/therapy/virologyen_GB
dc.subject.meshCytodiagnosisen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPapillomavirus Infectionsen_GB
dc.subject.meshRecurrenceen_GB
dc.subject.meshUterine Cervical Neoplasms/virologyen_GB
dc.titlePap smears for men: a vision of the future?en_GB
dc.contributor.departmentDepartment of Colorectal Surgery, St. Vincent's University Hospital, Elm Park,, Dublin 4, Ireland. sheng-fei.oon@ucd.ieen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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