Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.

Hdl Handle:
http://hdl.handle.net/10147/207563
Title:
Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.
Authors:
Prichard, R S; Cotter, M; Evoy, D; Gibbons, D; Collins, C; McDermott, E; Skehan, S
Affiliation:
St Vincent's University Hospital, Elm Park, Dublin 4 ruthprichard@rcsi.ie
Citation:
Ir Med J. 2011 Jun;104(6):177-9.
Journal:
Irish medical journal
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207563
PubMed ID:
22111394
Abstract:
Fluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients.
Language:
eng
MeSH:
Aged; Carcinoma, Papillary/pathology/radionuclide imaging; Female; Fluorodeoxyglucose F18/diagnostic use; Humans; *Incidental Findings; Male; Middle Aged; *Positron-Emission Tomography and Computed Tomography; Radiopharmaceuticals/diagnostic use; Retrospective Studies; Thyroid Neoplasms/pathology/*radionuclide imaging; *Whole Body Imaging
ISSN:
0332-3102 (Print); 0332-3102 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorPrichard, R Sen_GB
dc.contributor.authorCotter, Men_GB
dc.contributor.authorEvoy, Den_GB
dc.contributor.authorGibbons, Den_GB
dc.contributor.authorCollins, Cen_GB
dc.contributor.authorMcDermott, Een_GB
dc.contributor.authorSkehan, Sen_GB
dc.date.accessioned2012-02-01T10:31:27Z-
dc.date.available2012-02-01T10:31:27Z-
dc.date.issued2012-02-01T10:31:27Z-
dc.identifier.citationIr Med J. 2011 Jun;104(6):177-9.en_GB
dc.identifier.issn0332-3102 (Print)en_GB
dc.identifier.issn0332-3102 (Linking)en_GB
dc.identifier.pmid22111394en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207563-
dc.description.abstractFluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients.en_GB
dc.language.isoengen_GB
dc.subject.meshAgeden_GB
dc.subject.meshCarcinoma, Papillary/pathology/radionuclide imagingen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFluorodeoxyglucose F18/diagnostic useen_GB
dc.subject.meshHumansen_GB
dc.subject.mesh*Incidental Findingsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.mesh*Positron-Emission Tomography and Computed Tomographyen_GB
dc.subject.meshRadiopharmaceuticals/diagnostic useen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshThyroid Neoplasms/pathology/*radionuclide imagingen_GB
dc.subject.mesh*Whole Body Imagingen_GB
dc.titleFocal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.en_GB
dc.contributor.departmentSt Vincent's University Hospital, Elm Park, Dublin 4 ruthprichard@rcsi.ieen_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceLeinster-
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