Evaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.

Hdl Handle:
http://hdl.handle.net/10147/207512
Title:
Evaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.
Authors:
Mahdy, Saad; Khan, Ehtesham I; Attia, M; O'Brien, B P; Seigne, Patrick
Affiliation:
Department of Anaesthesia and Intensive Care Medicine, St Vincent's University, Hospital, Dublin 4, Ireland.
Citation:
Middle East J Anesthesiol. 2009 Jun;20(2):219-23.
Journal:
Middle East journal of anesthesiology
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207512
PubMed ID:
19583069
Abstract:
OBJECTIVE AND METHODS: Anemia is a common problem in the ICU population. Most patients are anemic at admission, their hemoglobin concentrations declining further thereafter. The aim of the present study was to evaluate the effect of a combination strategy, involving closed arterial blood gas sampling and the use of pediatric vials for phlebotomy (Group A), on the sampling-induced blood loss and the rate of decline in hemoglobin in adult ICU patients. Combination (Group A) was compared to the current standard technique of arterial line sampling and adult vial phlebotomy (Group B) in a prospective, randomised, ethically-approved trial for the first 72 hours of their ICU stay. Peri-operative, oncology, coagulopathic and uremic patients were excluded. All other ICU patients with arterial cannulae and predicted to stay beyond 3 days, were enrolled. RESULTS: 39 patients entered the study, 20 in Group A, and 19 in Group B. Data collection was complete for all. There was a statistically significant difference in sampling-induced blood loss between the groups over the first 72 hours of treatment (mean +/- standard deviation: 15.16 +/- 5.3 ml Group A vs 45.11 +/- 14 ml Group B, p<0.001). There was a smaller decline in mean hemoglobin level, which was not statistically significant (0.79 +/- 0.6 g/dL vs 1.30 +/- 1.13, p = 0.09). CONCLUSIONS: Overall, this strategy reduced measurable blood losses from phlebotomy. In larger trials it might also preserve hemoglobin levels.
Language:
eng
MeSH:
Anemia/*therapy; Blood Gas Analysis/methods; Hemoglobins/*metabolism; Humans; Intensive Care/methods; Phlebotomy/instrumentation/*methods; Pilot Projects; Prospective Studies
ISSN:
0544-0440 (Print); 0544-0440 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorMahdy, Saaden_GB
dc.contributor.authorKhan, Ehtesham Ien_GB
dc.contributor.authorAttia, Men_GB
dc.contributor.authorO'Brien, B Pen_GB
dc.contributor.authorSeigne, Patricken_GB
dc.date.accessioned2012-02-01T10:29:56Z-
dc.date.available2012-02-01T10:29:56Z-
dc.date.issued2012-02-01T10:29:56Z-
dc.identifier.citationMiddle East J Anesthesiol. 2009 Jun;20(2):219-23.en_GB
dc.identifier.issn0544-0440 (Print)en_GB
dc.identifier.issn0544-0440 (Linking)en_GB
dc.identifier.pmid19583069en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207512-
dc.description.abstractOBJECTIVE AND METHODS: Anemia is a common problem in the ICU population. Most patients are anemic at admission, their hemoglobin concentrations declining further thereafter. The aim of the present study was to evaluate the effect of a combination strategy, involving closed arterial blood gas sampling and the use of pediatric vials for phlebotomy (Group A), on the sampling-induced blood loss and the rate of decline in hemoglobin in adult ICU patients. Combination (Group A) was compared to the current standard technique of arterial line sampling and adult vial phlebotomy (Group B) in a prospective, randomised, ethically-approved trial for the first 72 hours of their ICU stay. Peri-operative, oncology, coagulopathic and uremic patients were excluded. All other ICU patients with arterial cannulae and predicted to stay beyond 3 days, were enrolled. RESULTS: 39 patients entered the study, 20 in Group A, and 19 in Group B. Data collection was complete for all. There was a statistically significant difference in sampling-induced blood loss between the groups over the first 72 hours of treatment (mean +/- standard deviation: 15.16 +/- 5.3 ml Group A vs 45.11 +/- 14 ml Group B, p<0.001). There was a smaller decline in mean hemoglobin level, which was not statistically significant (0.79 +/- 0.6 g/dL vs 1.30 +/- 1.13, p = 0.09). CONCLUSIONS: Overall, this strategy reduced measurable blood losses from phlebotomy. In larger trials it might also preserve hemoglobin levels.en_GB
dc.language.isoengen_GB
dc.subject.meshAnemia/*therapyen_GB
dc.subject.meshBlood Gas Analysis/methodsen_GB
dc.subject.meshHemoglobins/*metabolismen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIntensive Care/methodsen_GB
dc.subject.meshPhlebotomy/instrumentation/*methodsen_GB
dc.subject.meshPilot Projectsen_GB
dc.subject.meshProspective Studiesen_GB
dc.titleEvaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.en_GB
dc.contributor.departmentDepartment of Anaesthesia and Intensive Care Medicine, St Vincent's University, Hospital, Dublin 4, Ireland.en_GB
dc.identifier.journalMiddle East journal of anesthesiologyen_GB
dc.description.provinceLeinster-

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