Hdl Handle:
http://hdl.handle.net/10147/207486
Title:
Natural killer cells in psoriasis.
Authors:
Tobin, A M; Lynch, L; Kirby, B; O'Farrelly, C
Affiliation:
Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland., tobin.annemarie@gmail.com
Citation:
J Innate Immun. 2011;3(4):403-10. Epub 2011 May 25.
Journal:
Journal of innate immunity
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207486
DOI:
10.1159/000328011
PubMed ID:
21613780
Abstract:
Psoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-alpha, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions, natural killer and natural killer T cells appear to have a unique role. We review the evidence supporting a role for natural killer cells in psoriasis.
Language:
eng
MeSH:
Humans; Immunity, Innate; Killer Cells, Natural/*immunology; Psoriasis/*immunology/pathology/*physiopathology; Skin/immunology/pathology
ISSN:
1662-8128 (Electronic); 1662-811X (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorTobin, A Men_GB
dc.contributor.authorLynch, Len_GB
dc.contributor.authorKirby, Ben_GB
dc.contributor.authorO'Farrelly, Cen_GB
dc.date.accessioned2012-02-01T10:29:11Z-
dc.date.available2012-02-01T10:29:11Z-
dc.date.issued2012-02-01T10:29:11Z-
dc.identifier.citationJ Innate Immun. 2011;3(4):403-10. Epub 2011 May 25.en_GB
dc.identifier.issn1662-8128 (Electronic)en_GB
dc.identifier.issn1662-811X (Linking)en_GB
dc.identifier.pmid21613780en_GB
dc.identifier.doi10.1159/000328011en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207486-
dc.description.abstractPsoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-alpha, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions, natural killer and natural killer T cells appear to have a unique role. We review the evidence supporting a role for natural killer cells in psoriasis.en_GB
dc.language.isoengen_GB
dc.subject.meshHumansen_GB
dc.subject.meshImmunity, Innateen_GB
dc.subject.meshKiller Cells, Natural/*immunologyen_GB
dc.subject.meshPsoriasis/*immunology/pathology/*physiopathologyen_GB
dc.subject.meshSkin/immunology/pathologyen_GB
dc.titleNatural killer cells in psoriasis.en_GB
dc.contributor.departmentDepartment of Dermatology, St Vincent's University Hospital, Dublin, Ireland., tobin.annemarie@gmail.comen_GB
dc.identifier.journalJournal of innate immunityen_GB
dc.description.provinceLeinster-

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