Lymphatic malformations: a proposed management algorithm.

Hdl Handle:
http://hdl.handle.net/10147/207413
Title:
Lymphatic malformations: a proposed management algorithm.
Authors:
Oosthuizen, J C; Burns, P; Russell, J D
Affiliation:
Our Lady's Hospital for Sick Children, Crumlin, Dublin, D12, Republic of Ireland., C.oosth@gmail.com
Citation:
Int J Pediatr Otorhinolaryngol. 2010 Apr;74(4):398-403. Epub 2010 Feb 18.
Journal:
International journal of pediatric otorhinolaryngology
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207413
DOI:
10.1016/j.ijporl.2010.01.013
PubMed ID:
20170968
Abstract:
OBJECTIVE: The aim of this study was to develop a management algorithm for cervicofacial lymphatic malformations, based on the authors' experience in managing these lesions as well as current literature on the subject. STUDY DESIGN AND METHODS: A retrospective medical record review of all the patients treated for lymphatic malformations at our institution during a 10-year period (1998-2008) was performed. DATA COLLECTED: age at diagnosis, location and type of lesion, radiologic investigation performed, presenting symptoms, treatment modality used, complications and results achieved. RESULTS: 14 patients were identified. Eight (57%) male and six (43%) female. There was an equal distribution between the left and right sides. The majority (71%) of cases were diagnosed within the first year of life. The majority of lesions were located in the suprahyoid region. The predominant reason for referral was an asymptomatic mass in 7 cases (50%) followed by airway compromise (36%) and dysphagia (14%). Management options employed included: observation, OK-432 injection, surgical excision and laser therapy. In 5 cases (36%) a combination of these were used. CONCLUSION: Historically surgical excision has been the management option of choice for lymphatic malformations. However due to the morbidity and high complication rate associated this is increasingly being questioned. Recent advances in sclerotherapy e.g. OK-432 injection have also shown significant promise. Based on experience in managing these lesions as well as current literature the authors of this paper have developed an algorithm for the management of cervicofacial lymphatic malformations.
Language:
eng
MeSH:
Airway Obstruction/etiology; *Algorithms; Antineoplastic Agents/therapeutic use; Child; Child, Preschool; Deglutition Disorders/etiology; Diagnostic Imaging; Female; Head and Neck Neoplasms/diagnosis/*therapy; Humans; Infant; Infant, Newborn; Laser Therapy, Low-Level; Lasers, Solid-State; Lymphangioma/diagnosis/*therapy; Male; Neoplasm Recurrence, Local; Picibanil/therapeutic use; Retrospective Studies; Sclerotherapy
ISSN:
1872-8464 (Electronic); 0165-5876 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorOosthuizen, J Cen_GB
dc.contributor.authorBurns, Pen_GB
dc.contributor.authorRussell, J Den_GB
dc.date.accessioned2012-02-01T10:24:22Z-
dc.date.available2012-02-01T10:24:22Z-
dc.date.issued2012-02-01T10:24:22Z-
dc.identifier.citationInt J Pediatr Otorhinolaryngol. 2010 Apr;74(4):398-403. Epub 2010 Feb 18.en_GB
dc.identifier.issn1872-8464 (Electronic)en_GB
dc.identifier.issn0165-5876 (Linking)en_GB
dc.identifier.pmid20170968en_GB
dc.identifier.doi10.1016/j.ijporl.2010.01.013en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207413-
dc.description.abstractOBJECTIVE: The aim of this study was to develop a management algorithm for cervicofacial lymphatic malformations, based on the authors' experience in managing these lesions as well as current literature on the subject. STUDY DESIGN AND METHODS: A retrospective medical record review of all the patients treated for lymphatic malformations at our institution during a 10-year period (1998-2008) was performed. DATA COLLECTED: age at diagnosis, location and type of lesion, radiologic investigation performed, presenting symptoms, treatment modality used, complications and results achieved. RESULTS: 14 patients were identified. Eight (57%) male and six (43%) female. There was an equal distribution between the left and right sides. The majority (71%) of cases were diagnosed within the first year of life. The majority of lesions were located in the suprahyoid region. The predominant reason for referral was an asymptomatic mass in 7 cases (50%) followed by airway compromise (36%) and dysphagia (14%). Management options employed included: observation, OK-432 injection, surgical excision and laser therapy. In 5 cases (36%) a combination of these were used. CONCLUSION: Historically surgical excision has been the management option of choice for lymphatic malformations. However due to the morbidity and high complication rate associated this is increasingly being questioned. Recent advances in sclerotherapy e.g. OK-432 injection have also shown significant promise. Based on experience in managing these lesions as well as current literature the authors of this paper have developed an algorithm for the management of cervicofacial lymphatic malformations.en_GB
dc.language.isoengen_GB
dc.subject.meshAirway Obstruction/etiologyen_GB
dc.subject.mesh*Algorithmsen_GB
dc.subject.meshAntineoplastic Agents/therapeutic useen_GB
dc.subject.meshChilden_GB
dc.subject.meshChild, Preschoolen_GB
dc.subject.meshDeglutition Disorders/etiologyen_GB
dc.subject.meshDiagnostic Imagingen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHead and Neck Neoplasms/diagnosis/*therapyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfanten_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshLaser Therapy, Low-Levelen_GB
dc.subject.meshLasers, Solid-Stateen_GB
dc.subject.meshLymphangioma/diagnosis/*therapyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshNeoplasm Recurrence, Localen_GB
dc.subject.meshPicibanil/therapeutic useen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshSclerotherapyen_GB
dc.titleLymphatic malformations: a proposed management algorithm.en_GB
dc.contributor.departmentOur Lady's Hospital for Sick Children, Crumlin, Dublin, D12, Republic of Ireland., C.oosth@gmail.comen_GB
dc.identifier.journalInternational journal of pediatric otorhinolaryngologyen_GB
dc.description.provinceLeinster-

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