Congenital diaphragmatic hernia: neonatal outcomes following referral to a paediatric surgical centre.

Hdl Handle:
http://hdl.handle.net/10147/207392
Title:
Congenital diaphragmatic hernia: neonatal outcomes following referral to a paediatric surgical centre.
Authors:
Chukwu, J; Iro, C; Donoghue, V; McCallion, N; Murphy, J F; Quinn, F; Healy, M; Molloy, E J
Affiliation:
Department of Neonatology, Our Lady's Children's Hospital, Crumlin, Dublin 12.
Citation:
Ir Med J. 2009 Sep;102(8):260-1.
Journal:
Irish medical journal
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207392
PubMed ID:
19873868
Abstract:
Congenital diaphragmatic hernia (CDH) is a rare malformation observed in approximately 1 in 3000 live births. Estimates of postnatal survival range from 50 to 70% despite advances in neonatal care. Antenatal diagnosis is associated with termination of pregnancy in 25-50% pregnancy internationally which may not be reflective of the Irish population. We aimed to evaluate the mortality of infants with CDH who survived to admission in a tertiary referral paediatric hospital between 1996 and 2007. The Hospital In-Patient Enquiry system was used to determine the number of neonatal referrals for CDH to OLHSC between 1996 and 2007. Mortality, sex distribution, length of patient stay and the number of cases per year were examined. 141 neonates with CDH were over 12 years with approximately 12 referrals per annum of which 82 (58%) were male and 59 (42%) female. The average length of stay in the hospital was 33 (range 0-364) days. Overall 71% of the patients survived to discharge. In the first epoch (1996-2001) survival was 63% compared with 78% in the later epoch (2002-7). The overall survival for neonates with CDH presenting to OLCHC during the 12 year-period was 71% although this improved to 78% in recent epoch. Further study of associated congenital anomalies, number of terminations of pregnancy, complexity of the diaphragmatic defect and degree of pulmonary hypertension are required to compare this population with other international centres.
Language:
eng
MeSH:
Female; Hernia, Diaphragmatic/*congenital/mortality/*surgery; *Hospital Mortality; Hospitals, Pediatric/*statistics & numerical data; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Ireland; Length of Stay/statistics & numerical data; Male; *Referral and Consultation; Treatment Outcome
ISSN:
0332-3102 (Print); 0332-3102 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorChukwu, Jen_GB
dc.contributor.authorIro, Cen_GB
dc.contributor.authorDonoghue, Ven_GB
dc.contributor.authorMcCallion, Nen_GB
dc.contributor.authorMurphy, J Fen_GB
dc.contributor.authorQuinn, Fen_GB
dc.contributor.authorHealy, Men_GB
dc.contributor.authorMolloy, E Jen_GB
dc.date.accessioned2012-02-01T10:23:49Z-
dc.date.available2012-02-01T10:23:49Z-
dc.date.issued2012-02-01T10:23:49Z-
dc.identifier.citationIr Med J. 2009 Sep;102(8):260-1.en_GB
dc.identifier.issn0332-3102 (Print)en_GB
dc.identifier.issn0332-3102 (Linking)en_GB
dc.identifier.pmid19873868en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207392-
dc.description.abstractCongenital diaphragmatic hernia (CDH) is a rare malformation observed in approximately 1 in 3000 live births. Estimates of postnatal survival range from 50 to 70% despite advances in neonatal care. Antenatal diagnosis is associated with termination of pregnancy in 25-50% pregnancy internationally which may not be reflective of the Irish population. We aimed to evaluate the mortality of infants with CDH who survived to admission in a tertiary referral paediatric hospital between 1996 and 2007. The Hospital In-Patient Enquiry system was used to determine the number of neonatal referrals for CDH to OLHSC between 1996 and 2007. Mortality, sex distribution, length of patient stay and the number of cases per year were examined. 141 neonates with CDH were over 12 years with approximately 12 referrals per annum of which 82 (58%) were male and 59 (42%) female. The average length of stay in the hospital was 33 (range 0-364) days. Overall 71% of the patients survived to discharge. In the first epoch (1996-2001) survival was 63% compared with 78% in the later epoch (2002-7). The overall survival for neonates with CDH presenting to OLCHC during the 12 year-period was 71% although this improved to 78% in recent epoch. Further study of associated congenital anomalies, number of terminations of pregnancy, complexity of the diaphragmatic defect and degree of pulmonary hypertension are required to compare this population with other international centres.en_GB
dc.language.isoengen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHernia, Diaphragmatic/*congenital/mortality/*surgeryen_GB
dc.subject.mesh*Hospital Mortalityen_GB
dc.subject.meshHospitals, Pediatric/*statistics & numerical dataen_GB
dc.subject.meshHumansen_GB
dc.subject.meshHypertension, Pulmonaryen_GB
dc.subject.meshInfanten_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshIrelanden_GB
dc.subject.meshLength of Stay/statistics & numerical dataen_GB
dc.subject.meshMaleen_GB
dc.subject.mesh*Referral and Consultationen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.titleCongenital diaphragmatic hernia: neonatal outcomes following referral to a paediatric surgical centre.en_GB
dc.contributor.departmentDepartment of Neonatology, Our Lady's Children's Hospital, Crumlin, Dublin 12.en_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceLeinster-

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