Referral patterns of patients with liver metastases due to colorectal cancer for resection.

Hdl Handle:
http://hdl.handle.net/10147/207371
Title:
Referral patterns of patients with liver metastases due to colorectal cancer for resection.
Authors:
Al-Sahaf, O; Al-Azawi, Dhafir; Al-Khudairy, Ammar; Fauzi, Mohammad Z; El-Masry, Sherif; Gilen, Peter
Affiliation:
Department of General Surgery, Our Lady of Lourdes Hospital, Drogheda, Co.,, Louth, Ireland. Usama_sahaf70@hotmail.com
Citation:
Int J Colorectal Dis. 2009 Jan;24(1):79-82. Epub 2008 Aug 12.
Journal:
International journal of colorectal disease
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207371
DOI:
10.1007/s00384-008-0561-6
PubMed ID:
18696085
Abstract:
INTRODUCTION: Colorectal carcinoma accounts for 10% of cancer deaths in the Western World, with the liver being the most common site of distant metastases. Resection of liver metastases is the treatment of choice, with a 5-year survival rate of 35%. However, only 5-10% of patients are suitable for resection at presentation. AIMS: To examine the referral pattern of patients with liver metastases to a specialist hepatic unit for resection. METHODOLOGY: Retrospective review of patient's charts diagnosed with colorectal liver metastases over a 10-year period. RESULTS: One hundred nine (38 women, 71 men) patients with liver metastases were included, mean age 61 years; 79 and 30 patients had synchronous and metachronus metastases, respectively. Ten criteria for referral were identified; the referral rate was 8.25%, with a resection rate of 0.9%. Forty two percent of the patients had palliative chemotherapy; 42% had symptomatic treatment. CONCLUSION: This study highlights the advanced stage of colorectal cancer at presentation; in light of modern evidence-based, centre-oriented therapy of liver metastasis, we conclude that criteria of referral for resection should be based on the availability of treatment modalities.
Language:
eng
MeSH:
Adult; Age Factors; Aged; Aged, 80 and over; Colorectal Neoplasms/*pathology; Female; Hepatectomy; Humans; Liver Neoplasms/mortality/pathology/*secondary/*surgery; Male; Middle Aged; Palliative Care/statistics & numerical data; Prognosis; Referral and Consultation/*statistics & numerical data; Retrospective Studies
ISSN:
0179-1958 (Print); 0179-1958 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorAl-Sahaf, Oen_GB
dc.contributor.authorAl-Azawi, Dhafiren_GB
dc.contributor.authorAl-Khudairy, Ammaren_GB
dc.contributor.authorFauzi, Mohammad Zen_GB
dc.contributor.authorEl-Masry, Sherifen_GB
dc.contributor.authorGilen, Peteren_GB
dc.date.accessioned2012-02-01T10:21:49Z-
dc.date.available2012-02-01T10:21:49Z-
dc.date.issued2012-02-01T10:21:49Z-
dc.identifier.citationInt J Colorectal Dis. 2009 Jan;24(1):79-82. Epub 2008 Aug 12.en_GB
dc.identifier.issn0179-1958 (Print)en_GB
dc.identifier.issn0179-1958 (Linking)en_GB
dc.identifier.pmid18696085en_GB
dc.identifier.doi10.1007/s00384-008-0561-6en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207371-
dc.description.abstractINTRODUCTION: Colorectal carcinoma accounts for 10% of cancer deaths in the Western World, with the liver being the most common site of distant metastases. Resection of liver metastases is the treatment of choice, with a 5-year survival rate of 35%. However, only 5-10% of patients are suitable for resection at presentation. AIMS: To examine the referral pattern of patients with liver metastases to a specialist hepatic unit for resection. METHODOLOGY: Retrospective review of patient's charts diagnosed with colorectal liver metastases over a 10-year period. RESULTS: One hundred nine (38 women, 71 men) patients with liver metastases were included, mean age 61 years; 79 and 30 patients had synchronous and metachronus metastases, respectively. Ten criteria for referral were identified; the referral rate was 8.25%, with a resection rate of 0.9%. Forty two percent of the patients had palliative chemotherapy; 42% had symptomatic treatment. CONCLUSION: This study highlights the advanced stage of colorectal cancer at presentation; in light of modern evidence-based, centre-oriented therapy of liver metastasis, we conclude that criteria of referral for resection should be based on the availability of treatment modalities.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAge Factorsen_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshColorectal Neoplasms/*pathologyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHepatectomyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLiver Neoplasms/mortality/pathology/*secondary/*surgeryen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPalliative Care/statistics & numerical dataen_GB
dc.subject.meshPrognosisen_GB
dc.subject.meshReferral and Consultation/*statistics & numerical dataen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.titleReferral patterns of patients with liver metastases due to colorectal cancer for resection.en_GB
dc.contributor.departmentDepartment of General Surgery, Our Lady of Lourdes Hospital, Drogheda, Co.,, Louth, Ireland. Usama_sahaf70@hotmail.comen_GB
dc.identifier.journalInternational journal of colorectal diseaseen_GB
dc.description.provinceLeinster-

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