Identification and Characterization of Prodromal Risk Syndromes in Young Adolescents in the Community: A Population-Based Clinical Interview Study.

Hdl Handle:
http://hdl.handle.net/10147/207284
Title:
Identification and Characterization of Prodromal Risk Syndromes in Young Adolescents in the Community: A Population-Based Clinical Interview Study.
Affiliation:
1Department of Psychiatry, Royal College of Surgeons in Ireland, Education and, Research Centre, Beaumont Hospital, Dublin 9, Ireland.
Citation:
Schizophr Bull. 2011 Nov 17.
Journal:
Schizophrenia bulletin
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207284
DOI:
10.1093/schbul/sbr164
PubMed ID:
22101962
Abstract:
While a great deal of research has been conducted on prodromal risk syndromes in relation to help-seeking individuals who present to the clinic, there is a lack of research on prodromal risk syndromes in the general population. The current study aimed first to establish whether prodromal risk syndromes could be detected in non-help-seeking community-based adolescents and secondly to characterize this group in terms of Axis-1 psychopathology and general functioning. We conducted in-depth clinical interviews with a population sample of 212 school-going adolescents in order to assess for prodromal risk syndromes, Axis-1 psychopathology, and global (social/occupational) functioning. Between 0.9% and 8% of the community sample met criteria for a risk syndrome, depending on varying disability criteria. The risk syndrome group had a higher prevalence of co-occurring nonpsychotic Axis-1 psychiatric disorders (OR = 4.77, 95% CI = 1.81-12.52; P < .01) and poorer global functioning (F = 24.5, df = 1, P < .0001) compared with controls. Individuals in the community who fulfill criteria for prodromal risk syndromes demonstrate strong similarities with clinically presenting risk syndrome patients not just in terms of psychotic symptom criteria but also in terms of co-occurring psychopathology and global functioning.
Language:
ENG
ISSN:
1745-1701 (Electronic); 0586-7614 (Linking)

Full metadata record

DC FieldValue Language
dc.date.accessioned2012-02-01T10:03:59Z-
dc.date.available2012-02-01T10:03:59Z-
dc.date.issued2012-02-01T10:03:59Z-
dc.identifier.citationSchizophr Bull. 2011 Nov 17.en_GB
dc.identifier.issn1745-1701 (Electronic)en_GB
dc.identifier.issn0586-7614 (Linking)en_GB
dc.identifier.pmid22101962en_GB
dc.identifier.doi10.1093/schbul/sbr164en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207284-
dc.description.abstractWhile a great deal of research has been conducted on prodromal risk syndromes in relation to help-seeking individuals who present to the clinic, there is a lack of research on prodromal risk syndromes in the general population. The current study aimed first to establish whether prodromal risk syndromes could be detected in non-help-seeking community-based adolescents and secondly to characterize this group in terms of Axis-1 psychopathology and general functioning. We conducted in-depth clinical interviews with a population sample of 212 school-going adolescents in order to assess for prodromal risk syndromes, Axis-1 psychopathology, and global (social/occupational) functioning. Between 0.9% and 8% of the community sample met criteria for a risk syndrome, depending on varying disability criteria. The risk syndrome group had a higher prevalence of co-occurring nonpsychotic Axis-1 psychiatric disorders (OR = 4.77, 95% CI = 1.81-12.52; P < .01) and poorer global functioning (F = 24.5, df = 1, P < .0001) compared with controls. Individuals in the community who fulfill criteria for prodromal risk syndromes demonstrate strong similarities with clinically presenting risk syndrome patients not just in terms of psychotic symptom criteria but also in terms of co-occurring psychopathology and global functioning.en_GB
dc.language.isoENGen_GB
dc.titleIdentification and Characterization of Prodromal Risk Syndromes in Young Adolescents in the Community: A Population-Based Clinical Interview Study.en_GB
dc.contributor.department1Department of Psychiatry, Royal College of Surgeons in Ireland, Education and, Research Centre, Beaumont Hospital, Dublin 9, Ireland.en_GB
dc.identifier.journalSchizophrenia bulletinen_GB
dc.description.provinceLeinster-

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