Male lupus: a diagnosis often delayed--a case series and review of the literature.

Hdl Handle:
http://hdl.handle.net/10147/207268
Title:
Male lupus: a diagnosis often delayed--a case series and review of the literature.
Authors:
Ambrose, N L; Kearns, G; Mohammad, A
Affiliation:
Rheumatology Department, Beaumont Hospital, Dublin, Ireland., nambrose2001@yahoo.co.uk
Citation:
Ir J Med Sci. 2011 Mar;180(1):279-82. Epub 2009 Oct 28.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207268
DOI:
10.1007/s11845-009-0438-x
PubMed ID:
19862568
Abstract:
INTRODUCTION: Systemic lupus erythematosus (SLE) is an auto-immune disease that is characterised by autoantibody production. Male lupus is rare, apart from at either end of the age spectrum. AIM: In this series, we review the histories of six male lupus patients attending our service. RESULTS: Our patients presented in middle age and tended to develop haematological abnormalities, renal involvement and neurological manifestations which preceded the onset of their skin and joint complaints. Our patients accrued damage rapidly and overall did badly. They tended to respond sub-optimally to standard treatments. These cases highlight the need an increased awareness that male SLE patients present with a wide variety of symptoms, and that they accrue damage quickly. There is a need for timely diagnosis and appropriate initiation of treatment. This may help avoid preventable organ damage and increase the survival of men with SLE.
Language:
eng
MeSH:
Adult; Aged; Fatal Outcome; Glucocorticoids/administration & dosage; Humans; Lupus Erythematosus, Systemic/*diagnosis/drug therapy; Male; Middle Aged; Prednisolone/administration & dosage
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorAmbrose, N Len_GB
dc.contributor.authorKearns, Gen_GB
dc.contributor.authorMohammad, Aen_GB
dc.date.accessioned2012-02-01T10:03:35Z-
dc.date.available2012-02-01T10:03:35Z-
dc.date.issued2012-02-01T10:03:35Z-
dc.identifier.citationIr J Med Sci. 2011 Mar;180(1):279-82. Epub 2009 Oct 28.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid19862568en_GB
dc.identifier.doi10.1007/s11845-009-0438-xen_GB
dc.identifier.urihttp://hdl.handle.net/10147/207268-
dc.description.abstractINTRODUCTION: Systemic lupus erythematosus (SLE) is an auto-immune disease that is characterised by autoantibody production. Male lupus is rare, apart from at either end of the age spectrum. AIM: In this series, we review the histories of six male lupus patients attending our service. RESULTS: Our patients presented in middle age and tended to develop haematological abnormalities, renal involvement and neurological manifestations which preceded the onset of their skin and joint complaints. Our patients accrued damage rapidly and overall did badly. They tended to respond sub-optimally to standard treatments. These cases highlight the need an increased awareness that male SLE patients present with a wide variety of symptoms, and that they accrue damage quickly. There is a need for timely diagnosis and appropriate initiation of treatment. This may help avoid preventable organ damage and increase the survival of men with SLE.en_GB
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshFatal Outcomeen_GB
dc.subject.meshGlucocorticoids/administration & dosageen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLupus Erythematosus, Systemic/*diagnosis/drug therapyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPrednisolone/administration & dosageen_GB
dc.titleMale lupus: a diagnosis often delayed--a case series and review of the literature.en_GB
dc.contributor.departmentRheumatology Department, Beaumont Hospital, Dublin, Ireland., nambrose2001@yahoo.co.uken_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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