Nanotechnology and its relationship to interventional radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.

Hdl Handle:
http://hdl.handle.net/10147/207237
Title:
Nanotechnology and its relationship to interventional radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.
Authors:
Power, Sarah; Slattery, Michael M; Lee, Michael J
Affiliation:
Department of Radiology, Beaumont Hospital, Beaumont Road, PO Box 1297, Dublin 9,, Ireland.
Citation:
Cardiovasc Intervent Radiol. 2011 Aug;34(4):676-90. Epub 2010 Sep 16.
Journal:
Cardiovascular and interventional radiology
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207237
DOI:
10.1007/s00270-010-9967-y
PubMed ID:
20845040
Abstract:
Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.
Language:
eng
MeSH:
Antineoplastic Agents/administration & dosage; Catheter Ablation/methods; Drug Delivery Systems/*methods; Hemostatic Techniques; Humans; Hyperthermia, Induced/*methods; Magnetite Nanoparticles; Muscle, Smooth, Vascular/drug effects; Nanotechnology/*methods; Neoplasms/*therapy; Radiology, Interventional/*methods; Stents; Thrombolytic Therapy/methods; Treatment Outcome; Vascular Diseases/*therapy
ISSN:
1432-086X (Electronic); 0174-1551 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorPower, Sarahen_GB
dc.contributor.authorSlattery, Michael Men_GB
dc.contributor.authorLee, Michael Jen_GB
dc.date.accessioned2012-02-01T10:02:44Z-
dc.date.available2012-02-01T10:02:44Z-
dc.date.issued2012-02-01T10:02:44Z-
dc.identifier.citationCardiovasc Intervent Radiol. 2011 Aug;34(4):676-90. Epub 2010 Sep 16.en_GB
dc.identifier.issn1432-086X (Electronic)en_GB
dc.identifier.issn0174-1551 (Linking)en_GB
dc.identifier.pmid20845040en_GB
dc.identifier.doi10.1007/s00270-010-9967-yen_GB
dc.identifier.urihttp://hdl.handle.net/10147/207237-
dc.description.abstractNanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.en_GB
dc.language.isoengen_GB
dc.subject.meshAntineoplastic Agents/administration & dosageen_GB
dc.subject.meshCatheter Ablation/methodsen_GB
dc.subject.meshDrug Delivery Systems/*methodsen_GB
dc.subject.meshHemostatic Techniquesen_GB
dc.subject.meshHumansen_GB
dc.subject.meshHyperthermia, Induced/*methodsen_GB
dc.subject.meshMagnetite Nanoparticlesen_GB
dc.subject.meshMuscle, Smooth, Vascular/drug effectsen_GB
dc.subject.meshNanotechnology/*methodsen_GB
dc.subject.meshNeoplasms/*therapyen_GB
dc.subject.meshRadiology, Interventional/*methodsen_GB
dc.subject.meshStentsen_GB
dc.subject.meshThrombolytic Therapy/methodsen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshVascular Diseases/*therapyen_GB
dc.titleNanotechnology and its relationship to interventional radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.en_GB
dc.contributor.departmentDepartment of Radiology, Beaumont Hospital, Beaumont Road, PO Box 1297, Dublin 9,, Ireland.en_GB
dc.identifier.journalCardiovascular and interventional radiologyen_GB
dc.description.provinceLeinster-
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