Prevalence of left-sided melanomas in an Irish population.

Hdl Handle:
http://hdl.handle.net/10147/207116
Title:
Prevalence of left-sided melanomas in an Irish population.
Authors:
de Blacam, C; Ho, W L; Acton, C; Murphy, G; Kneafsey, B; Hill, A D K
Affiliation:
Department of Surgery, Beaumont Hospital, Royal College of Surgeons in Ireland,, Dublin, Ireland. catherinedeblacam@rcsi.ie
Citation:
Ir J Med Sci. 2011 Sep;180(3):727-30. Epub 2011 Apr 17.
Journal:
Irish journal of medical science
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207116
DOI:
10.1007/s11845-011-0713-5
PubMed ID:
21499924
Abstract:
BACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using chi(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.
Language:
eng
MeSH:
Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Ireland; Male; Melanoma/*pathology; Middle Aged; Skin Neoplasms/*pathology; Young Adult
ISSN:
1863-4362 (Electronic); 0021-1265 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorde Blacam, Cen_GB
dc.contributor.authorHo, W Len_GB
dc.contributor.authorActon, Cen_GB
dc.contributor.authorMurphy, Gen_GB
dc.contributor.authorKneafsey, Ben_GB
dc.contributor.authorHill, A D Ken_GB
dc.date.accessioned2012-02-01T09:59:37Z-
dc.date.available2012-02-01T09:59:37Z-
dc.date.issued2012-02-01T09:59:37Z-
dc.identifier.citationIr J Med Sci. 2011 Sep;180(3):727-30. Epub 2011 Apr 17.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid21499924en_GB
dc.identifier.doi10.1007/s11845-011-0713-5en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207116-
dc.description.abstractBACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using chi(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.en_GB
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshChilden_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIrelanden_GB
dc.subject.meshMaleen_GB
dc.subject.meshMelanoma/*pathologyen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshSkin Neoplasms/*pathologyen_GB
dc.subject.meshYoung Adulten_GB
dc.titlePrevalence of left-sided melanomas in an Irish population.en_GB
dc.contributor.departmentDepartment of Surgery, Beaumont Hospital, Royal College of Surgeons in Ireland,, Dublin, Ireland. catherinedeblacam@rcsi.ieen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster-

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