Affiliation
Department of Surgery, Beaumont Hospital, Royal College of Surgeons in Ireland,, Dublin, Ireland. catherinedeblacam@rcsi.ieIssue Date
2012-02-01T09:59:37ZMeSH
AdolescentAdult
Aged
Aged, 80 and over
Child
Female
Humans
Ireland
Male
Melanoma/*pathology
Middle Aged
Skin Neoplasms/*pathology
Young Adult
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Show full item recordCitation
Ir J Med Sci. 2011 Sep;180(3):727-30. Epub 2011 Apr 17.Journal
Irish journal of medical scienceDOI
10.1007/s11845-011-0713-5PubMed ID
21499924Abstract
BACKGROUND: A predominance of melanomas on the left side of the body has recently been described. No associations between tumour laterality and gender, age or anatomical site have been identified. AIM: The aim of this study was to investigate the prevalence of left-sided melanomas in an Irish population and to examine potential associations with various patient and tumour characteristics. METHODS: A retrospective chart review of patients with cutaneous melanoma who were treated over a 10-year period was carried out. Lateral distribution of melanoma on either side of the body was compared using chi(2) analysis and evaluated by gender, age group, anatomic location, histologic subtype and Breslow depth. RESULTS: More melanomas occurred on the left side (57%, P = 0.015), and this finding was particularly significant in females. For both genders combined, there were no statistically significant differences in laterality by age group, anatomic location, type of melanoma and Breslow depth. There were significantly more superficial spreading melanomas on the left side in both men and women. CONCLUSIONS: This study demonstrates a predominance of left-sided melanomas in Irish patients. While a number of demographic and molecular associations have been proposed, further research is required to fully explain this phenomenon.Language
engISSN
1863-4362 (Electronic)0021-1265 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1007/s11845-011-0713-5
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