A 12-year review of Staphylococcus aureus bloodstream infections in haemodialysis patients: more work to be done.

Hdl Handle:
http://hdl.handle.net/10147/207004
Title:
A 12-year review of Staphylococcus aureus bloodstream infections in haemodialysis patients: more work to be done.
Authors:
Fitzgerald, S F; O'Gorman, J; Morris-Downes, M M; Crowley, R K; Donlon, S; Bajwa, R; Smyth, E G; Fitzpatrick, F; Conlon, P J; Humphreys, H
Affiliation:
Department of Microbiology, Beaumont Hospital, Dublin, Ireland., s.fitzgerald@svuh.ie
Citation:
J Hosp Infect. 2011 Nov;79(3):218-21.
Journal:
The Journal of hospital infection
Issue Date:
1-Feb-2012
URI:
http://hdl.handle.net/10147/207004
DOI:
10.1016/j.jhin.2011.06.015
PubMed ID:
21856042
Abstract:
Staphylococcus aureus bloodstream infections (BSI) are a significant cause of morbidity and mortality in haemodialysis patients. This study describes a 12-year retrospective review of S. aureus BSI in a large haemodialysis centre in a tertiary referral hospital. The overall rate of S. aureus BSI was 17.9 per 100 patient-years (range 9.7-36.8). The rate of meticillin-resistant S. aureus (MRSA) BSI was 5.6 per 100 patient-years (range 0.9-13.8). Infective complications occurred in 11% of episodes, the most common being infective endocarditis (7.6%). Ten percent of patients died within 30 days of S. aureus being isolated from blood. Most cases of S. aureus BSI (83%) were related to vascular catheters. The provision of lower-risk vascular access, such as arteriovenous fistulae, and reduced use of intravascular catheters should be priorities in all haemodialysis units. Where alternative vascular access cannot be established, interventions to reduce the risk of catheter-related infections should be implemented to reduce morbidity and mortality in this vulnerable patient group.
Language:
eng
MeSH:
Bacteremia/*epidemiology/microbiology/mortality; Catheter-Related Infections/epidemiology/microbiology/mortality; Cross Infection/epidemiology/microbiology/mortality; Endocarditis/epidemiology/microbiology; Female; Humans; Ireland/epidemiology; Male; Methicillin-Resistant Staphylococcus aureus/*isolation & purification; Renal Dialysis/*adverse effects; Risk Factors; Staphylococcal Infections/*epidemiology/microbiology/mortality; Staphylococcus aureus/*isolation & purification
ISSN:
1532-2939 (Electronic); 0195-6701 (Linking)

Full metadata record

DC FieldValue Language
dc.contributor.authorFitzgerald, S Fen_GB
dc.contributor.authorO'Gorman, Jen_GB
dc.contributor.authorMorris-Downes, M Men_GB
dc.contributor.authorCrowley, R Ken_GB
dc.contributor.authorDonlon, Sen_GB
dc.contributor.authorBajwa, Ren_GB
dc.contributor.authorSmyth, E Gen_GB
dc.contributor.authorFitzpatrick, Fen_GB
dc.contributor.authorConlon, P Jen_GB
dc.contributor.authorHumphreys, Hen_GB
dc.date.accessioned2012-02-01T09:57:25Z-
dc.date.available2012-02-01T09:57:25Z-
dc.date.issued2012-02-01T09:57:25Z-
dc.identifier.citationJ Hosp Infect. 2011 Nov;79(3):218-21.en_GB
dc.identifier.issn1532-2939 (Electronic)en_GB
dc.identifier.issn0195-6701 (Linking)en_GB
dc.identifier.pmid21856042en_GB
dc.identifier.doi10.1016/j.jhin.2011.06.015en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207004-
dc.description.abstractStaphylococcus aureus bloodstream infections (BSI) are a significant cause of morbidity and mortality in haemodialysis patients. This study describes a 12-year retrospective review of S. aureus BSI in a large haemodialysis centre in a tertiary referral hospital. The overall rate of S. aureus BSI was 17.9 per 100 patient-years (range 9.7-36.8). The rate of meticillin-resistant S. aureus (MRSA) BSI was 5.6 per 100 patient-years (range 0.9-13.8). Infective complications occurred in 11% of episodes, the most common being infective endocarditis (7.6%). Ten percent of patients died within 30 days of S. aureus being isolated from blood. Most cases of S. aureus BSI (83%) were related to vascular catheters. The provision of lower-risk vascular access, such as arteriovenous fistulae, and reduced use of intravascular catheters should be priorities in all haemodialysis units. Where alternative vascular access cannot be established, interventions to reduce the risk of catheter-related infections should be implemented to reduce morbidity and mortality in this vulnerable patient group.en_GB
dc.language.isoengen_GB
dc.subject.meshBacteremia/*epidemiology/microbiology/mortalityen_GB
dc.subject.meshCatheter-Related Infections/epidemiology/microbiology/mortalityen_GB
dc.subject.meshCross Infection/epidemiology/microbiology/mortalityen_GB
dc.subject.meshEndocarditis/epidemiology/microbiologyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIreland/epidemiologyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMethicillin-Resistant Staphylococcus aureus/*isolation & purificationen_GB
dc.subject.meshRenal Dialysis/*adverse effectsen_GB
dc.subject.meshRisk Factorsen_GB
dc.subject.meshStaphylococcal Infections/*epidemiology/microbiology/mortalityen_GB
dc.subject.meshStaphylococcus aureus/*isolation & purificationen_GB
dc.titleA 12-year review of Staphylococcus aureus bloodstream infections in haemodialysis patients: more work to be done.en_GB
dc.contributor.departmentDepartment of Microbiology, Beaumont Hospital, Dublin, Ireland., s.fitzgerald@svuh.ieen_GB
dc.identifier.journalThe Journal of hospital infectionen_GB
dc.description.provinceLeinster-

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